Titill: | Patient-reported Outcomes and Clinical Response in Patients with Moderate-to-severe Plaque Psoriasis Treated with Tonsillectomy: A Randomized Controlled Trial |
Höfundur: |
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Útgáfa: | 2017 |
Tungumál: | Enska |
Umfang: | 340-345 |
Háskóli/Stofnun: | Háskóli Íslands University of Iceland |
Svið: | Heilbrigðisvísindasvið (HÍ) School of Health Sciences (UI) |
Deild: | Læknadeild (HÍ) Faculty of Medicine (UI) |
Birtist í: | Acta Dermato Venereologica;97(3) |
ISSN: | 0001-5555 1651-2057 (eISSN) |
DOI: | 10.2340/00015555-2562 |
Efnisorð: | Psoriasis; Streptococcal throat infection; Tonsillectomy; Sóríasis; Háls-, nef- og eyrnasjúkdómar |
URI: | https://hdl.handle.net/20.500.11815/284 |
Tilvitnun:Patient-reported Outcomes and Clinical Response in Patients with Moderate-to-severe Plaque Psoriasis Treated with Tonsillectomy: A Randomized Controlled Trial. 2017, 97 (3):340-345 Acta Derm. Venereol.doi:10.2340/00015555-2562
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Útdráttur:Psoriasis is a chronic inflammatory skin disease with profound effects on patients’ health-related quality of life (HRQoL). Twenty-nine patients with plaque psoriasis and a history of streptococcal-associated psoriasis exacerbations were randomly assigned to tonsillectomy (n = 15) or control (n = 14) groups and followed for 24 months. Patients were evaluated with the Psoriasis Disability Index, Psoriasis Life Stress Inventory and Psoriasis Area and Severity Index. HRQoL and psoriasis-related stress improved significantly in the tonsillectomy group compared with the control group (p = 0.037 and p = 0.002, respectively), with a mean 50% improvement in HRQoL and a mean 59% improvement in psoriasis-induced stress. Clinical improvement correlated significantly with improved HRQoL (r = 0.297, p = 0.008) and psoriasis-related stress (r = 0.310, p = 0.005). Of the tonsillectomized patients, 87% concluded that the procedure was worthwhile. Tonsillectomy may improve quality of life for selected patients with plaque psoriasis.
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Leyfi:This is an open access article under the CC BY-NC license
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