IRIS: Recent submissions

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    Abatacept in rheumatoid arthritis : Survival on drug, clinical outcomes, and their predictors - Data from a large national quality register 
    Cagnotto, Giovanni; Willim, Minna; Nilsson, Jan Åke; Compagno, Michele; Jacobsson, Lennart T.H.; Saevarsdottir, Saedis; Turesson, Carl (2020-01-22)
    Background: There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. ...
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    Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different delivery systems in healthy volunteers and in psoriasis patients 
    Bruin, Gerard; Hockey, Hans Ulrich P.; La Stella, Phillip; Sigurgeirsson, Bárdur; Fu, Rong; Patekar, Manmath; Charef, Pascal; Woessner, Ralph; Boutouyrie-Dumont, Bruno (2020-02-01)
    Aims: The aim of the study was to compare the pharmacokinetics (PK), safety and tolerability of secukinumab with different devices for subcutaneous (s.c.) administration of 2 mL. Methods: A phase 1 study in healthy subjects with 6 devices to administer ...
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    A pooled-analysis of age and sex based coronary artery calcium scores percentiles 
    de Ronde, Maurice W.J.; Khoshiwal, Amir; Planken, R. Nils; Boekholdt, S. Matthijs; Biemond, Mariette; Budoff, Matthew J.; Cooil, Bruce; Lotufo, Paulo A.; Bensenor, Isabela M.; Ohmoto-Sekine, Yuki; Gudnason, Vilmundur; Aspelund, Thor; Gudmundsson, Elias Freyr; Zwinderman, Aeilko H.; Raggi, Paolo; Pinto-Sietsma, Sara Joan (2020-09-01)
    Background: Age and sex based coronary artery calcium score (CAC) percentiles have been used to improve coronary artery disease (CAD) risk prediction. However, the main limitation of the CACs percentiles currently in use is that they are often based ...
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    Coding and regulatory variants affect serum protein levels and common disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur; Gudjonsson, Alexander; Karim, Mohd A; Jonsson, Brynjolfur G (2020-05-08)
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    Antihypertensive medication uses and serum ACE2 levels 
    Emilsson, Valur; Gudmundsson, Elias F.; Aspelund, Thor; Jonsson, Brynjolfur G.; Gudjonsson, Alexander; Launer, Lenore J.; Jennings, Lori L.; Gudmundsdottir, Valborg; Gudnason, Vilmundur (2020-05-25)
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    ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19 
    Emilsson, Valur; Gudmundsson, Elias F; Aspelund, Thor; Jonsson, Brynjolfur G; Gudjonsson, Alexander; Launer, Lenore J.; Lamb, John R; Gudmundsdottir, Valborg; Jennings, Lori L; Gudnason, Vilmundur (2020-06-05)
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    Towards an app to estimate patient-specific perioperative femur fracture risk 
    Esposito, L.; Minutolo, V.; Gargiulo, P.; Jonsson, H.; Gislason, M. K.; Fraldi, M. (2020-09-01)
    Total Hip Arthroplasty has been one of the most successful surgical procedure in terms of patient outcomes and satisfaction. However, due to increase in life expectancy and the related incidence of age-dependent bone diseases, a growing number of cases ...
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    Erratum : Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy (PLoS ONE (2017) 12: 3 (e0172995) DOI: 10.1371/journal.pone.0172995) 
    Esslinger, Ulrike; Garnier, Sophie; Korniat, Agathe; Proust, Carole; Kararigas, Georgios; Müller-Nurasyid, Martina; Empana, Jean Philippe; Morley, Michael P.; Perret, Claire; Stark, Klaus; Bick, Alexander G.; Prasad, Sanjay K.; Kriebel, Jennifer; Li, Jin; Tiret, Laurence; Strauch, Konstantin; O'Regan, Declan P.; Marguiles, Kenneth B.; Seidman, Jonathan G.; Boutouyrie, Pierre; Lacolley, Patrick; Jouven, Xavier; Hengstenberg, Christian; Komajda, Michel; Hakonarson, Hakon; Isnard, Richard; Arbustini, Eloisa; Grallert, Harald; Cook, Stuart A.; Seidman, Christine E.; Regitz-Zagrosek, Vera; Cappola, Thomas P.; Charron, Philippe; Cambien, François; Villard, Eric (2020-02-01)
    Based on experiments conducted since this article's [1] publication, the authors have concluded that the protein-protein interaction results reported in Fig 4 are not reliable. In experiments done after the article was published, the authors observed ...
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    Spatio-temporal assessment of illicit drug use at large scale : evidence from 7 years of international wastewater monitoring 
    González-Mariño, Iria; Baz-Lomba, Jose Antonio; Alygizakis, Nikiforos A.; Andrés-Costa, Maria Jesús; Bade, Richard; Bannwarth, Anne; Barron, Leon P.; Been, Frederic; Benaglia, Lisa; Berset, Jean Daniel; Bijlsma, Lubertus; Bodík, Igor; Brenner, Asher; Brock, Andreas L.; Burgard, Daniel A.; Castrignanò, Erika; Celma, Alberto; Christophoridis, Christophoros E.; Covaci, Adrian; Delémont, Oliver; Devoogt, Pim; Devault, Damien A.; Dias, Mário J.; Emke, Erik; Esseiva, Pierre; Fatta-Kassinos, Despo; Fedorova, Ganna; Fytianos, Konstantinos; Gerber, Cobus; Grabic, Roman; Gracia-Lor, Emma; Grüner, Stefan; Gunnar, Teemu; Hapeshi, Evroula; Heath, Ester; Helm, Björn; Hernández, Félix; Kankaanpaa, Aino; Karolak, Sara; Kasprzyk-Hordern, Barbara; Krizman-Matasic, Ivona; Lai, Foon Yin; Lechowicz, Wojciech; Lopes, Alvaro; de Alda, Miren López; López-García, Ester; Löve, Arndís S.C.; Mastroianni, Nicola; McEneff, Gillian L.; Montes, Rosa; Munro, Kelly; Nefau, Thomas; Oberacher, Herbert; O’brien, Jake W.; Oertel, Reinhard; Olafsdottir, Kristin; Picó, Yolanda; Plósz, Benedek G.; Polesel, Fabio; Postigo, Cristina; Quintana, José Benito; Ramin, Pedram; Reid, Malcolm J.; Rice, Jack; Rodil, Rosario; Salgueiro-Gonzàlez, Noelia; Schubert, Sara; Senta, Ivan; Simões, Susana M.; Sremacki, Maja M.; Styszko, Katarzyna; Terzic, Senka; Thomaidis, Nikolaos S.; Thomas, Kevin V.; Tscharke, Ben J.; Udrisard, Robin; van Nuijs, Alexander L.N.; Yargeau, Viviane; Zuccato, Ettore; Castiglioni, Sara; Ort, Christoph (2020-01-01)
    Background and aims: Wastewater-based epidemiology is an additional indicator of drug use that is gaining reliability to complement the current established panel of indicators. The aims of this study were to: (i) assess spatial and temporal trends of ...
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    Capture of systemic anticancer medicines in pharmaceutical benefits scheme (PBS) data likely higher than previously reported 
    Favell, Dominique L.; Tang, Monica; Daniels, Benjamin; Vajdic, Claire M.; Zoega, Helga; Pearson, Salllie Anne (2020-06)
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    Erratum : Systems analysis and improvement approach to optimize the hypertension diagnosis and care cascade for PLHIV individuals (SAIA-HTN): A hybrid type III cluster randomized trial (Implementation Sci. (2020) 15:15 DOI: 10.1186/s13012-020-0973-4) 
    Gimbel, Sarah; Mocumbi, Ana Olga; Ásbjörnsdóttir, Kristjana; Coutinho, Joana; Andela, Leonel; Cebola, Bonifacio; Craine, Heidi; Crocker, Jonny; Hicks, Leecreesha; Holte, Sarah; Hossieke, Rodrigues; Itai, Edgar; Levin, Carol; Manaca, Nelia; Murgorgo, Filipe; Nhumba, Miguel; Pfeiffer, James; Ramiro, Isaias; Ronen, Keshet; Sotoodehnia, Nona; Uetela, Onei; Wagner, Anjuli; Weiner, Bryan J.; Sherr, Kenneth (2020-03-19)
    Following publication of the original article [1], the authors reported a typo in the title of the article. In this Correction the incorrect and correct title are shown, with the correction shown in bold. The original article has been corrected. ...
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    Evaluation of chlorella sorokiniana biomass recovery by using different chemical-based flocculants 
    Fonseca, Gustavo Graciano; Menegazzo, Mariana Lara; Ribeiro, Dagon Manoel; de Oliveira, Nathanya Nayla; Marques, Otavio Gonçalves Benites (2022-03)
    Introduction: The nature and the concentration of the chemical agents responsible for cell flocculation are the bottlenecks for microalgae recovery. The aim of the present study was to evaluate different chemical-based flocculants for Chlorella sorokiniana ...
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    A year of Covid-19 : Experiences and lessons learnt by small European island states - Cyprus, Iceland and Malta 
    Cuschieri, Sarah; Pallari, Elena; Hatziyianni, Amalia; Sigurvinsdottir, Rannveig; Sigfusdottir, Inga Dora; Sigurðardóttir, Árún Kristín (2022-04-01)
    Background: COVID-19 became a global pandemic within weeks, as every country including small states and islands experienced a surge in cases. Small islands are known to face several challenges in the quest to curb the viral spread, but with the absence ...
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    Remediation capacity of different microalgae in effluents derived from the cigarette butt cleaning process 
    Chiellini, Carolina; Mariotti, Lorenzo; Huarancca Reyes, Thais; de Arruda, Eduardo José; Fonseca, Gustavo Graciano; Guglielminetti, Lorenzo (2022-07-01)
    Microalgal-based remediation is an ecofriendly and cost-effective system for wastewater treatment. This study evaluated the capacity of microalgae in the remediation of wastewater from cleaning process of smoked cigarette butts (CB). At laboratory ...
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    Making Europe health literate : Including older adults in sparsely populated Arctic areas 
    Gústafsdóttir, Sonja Stelly; Sigurðardóttir, Árún Kristín; Mårtensson, Lena; Árnadóttir, Sólveig Ása (2022-12)
    Background Older people have been identified as having lower health literacy (HL) than the general population average. Living in sparsely populated Arctic regions involves unique health challenges that may influence HL. The research aim was to explore ...
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    Water mass transformation in the Iceland Sea : Contrasting two winters separated by four decades 
    Vage, Kjetil; Semper, Stefanie; Valdimarsson, Héðinn; Jónsson, Steingrímur; Pickart, Robert S.; Moore, G. W. K. (2022-08)
    Dense water masses formed in the Nordic Seas flow across the Greenland–Scotland Ridge and contribute substantially to the lower limb of the Atlantic Meridional Overturning Circulation. Originally considered an important source of dense water, the Iceland ...
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    Developing a woman-centered, inclusive definition of traumatic childbirth experiences : A discussion paper 
    Leinweber, Julia; Fontein-Kuipers, Yvonne; Thomson, Gill; Karlsdóttir, Sigfríður Inga; Nilsson, Christina; Ekström-Bergström, Anette; Olza, Ibone; Hadjigeorgiou, Eleni; Stramrood, Claire (2022-12)
    Introduction: Many women experience giving birth as traumatic. Although women's subjective experiences of trauma are considered the most important, currently there is no clear inclusive definition of a traumatic birth to help guide practice, education, ...
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    Active conventional treatment and three different biological treatments in early rheumatoid arthritis : Phase IV investigator initiated, randomised, observer blinded clinical trial 
    Hetland, Merete Lund; Haavardsholm, Espen A.; Rudin, Anna; Nordström, Dan; Nurmohamed, Michael; Gudbjornsson, Bjorn; Lampa, Jon; Hørslev-Petersen, Kim; Uhlig, Till; Grondal, Gerdur; Østergaard, Mikkel; Heiberg, Marte S.; Twisk, Jos; Lend, Kristina; Krabbe, Simon; Hyldstrup, Lise Hejl; Lindqvist, Joakim; Hultgård Ekwall, Anna Karin; Grøn, Kathrine Lederballe; Kapetanovic, Meliha; Faustini, Francesca; Tuompo, Riitta; Lorenzen, Tove; Cagnotto, Giovanni; Baecklund, Eva; Hendricks, Oliver; Vedder, Daisy; Sokka-Isler, Tuulikki; Husmark, Tomas; Ljoså, Maud Kristine Aga; Brodin, Eli; Ellingsen, Torkell; Söderbergh, Annika; Rizk, Milad; Olsson, Åsa Reckner; Larsson, Per; Uhrenholt, Line; Just, Søren Andreas; Stevens, David John; Laurberg, Trine Bay; Bakland, Gunnstein; Olsen, Inge C.; Van Vollenhoven, Ronald (2020-12-02)
    AbstractObjective To evaluate and compare benefits and harms of three biological treatments with different modes of action versus active conventional treatment in patients with early rheumatoid arthritis. Design Investigator initiated, randomised, open ...
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    Development of classification criteria for hand osteoarthritis : Comparative analyses of persons with and without hand osteoarthritis 
    Haugen, Ida K.; Felson, David T.; Abhishek, Abhishek; Berenbaum, Francis; Bierma-Zeinstra, Sita; Borgen, Tove; Herrero Beaumont, Gabriel; Ishimori, Mariko; Jonsson, Helgi; Kroon, Féline P.B.; Maheu, Emmanuel; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Van Der Heijde, Desirée; Wittoek, Ruth; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2020-06-25)
    Objectives Further knowledge about typical hand osteoarthritis (OA) characteristics is needed for the development of new classification criteria for hand OA. Methods In a cross-sectional multi-centre international study, a convenience sample of patients ...
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    Algengi og áhættuþættir lengdrar dvalar á gjörgæsludeild eftir kransæðahjáveituaðgerð 
    Gunnarsdóttir, Erla Liu Ting; Gunnarsdóttir, Sunna Lu Xi; Heimisdóttir, Alexandra Aldís; Heiðarsdóttir, Sunna Rún; Helgadóttir, Sólveig; Guðbjartsson, Tómas; Sigurðsson, Martin Ingi (2020-03)
    Introduction: To maximize the use of intensive care unit (ICU) resources, it is important to estimate the prevalence and risk factors for prolonged ICU unit stay after coronary artery bypass grafting (CABG) surgery. Material and methods: This retrospective ...