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Fletta eftir deild "Cancer Center"

Fletta eftir deild "Cancer Center"

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    Assessing thyroid cancer risk using polygenic risk scores 
    Liyanarachchi, Sandya; Gudmundsson, Julius; Ferkingstad, Egil; He, Huiling; Jónasson, Jón Gunnlaugur; Tragante, Vinicius; Asselbergs, Folkert W.; Xu, Li; Kiemeney, Lambertus A.; Netea-Maier, Romana T.; Mayordomo, Jose I.; Plantinga, Theo S.; Hjartarson, Hannes; Hrafnkelsson, Jón; Sturgis, Erich M.; Brock, Pamela; Nabhan, Fadi; Thorleifsson, Gudmar; Ringel, Matthew D.; Stefansson, Kari; de la Chapelle, Albert (2020-03-17)
    Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk. Most of these SNPs are common variants with small to moderate effect sizes. Here we assessed ...
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    Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study. 
    Jakubowska, A; Rozkrut, D; Antoniou, A; Hamann, U; Scott, R J; McGuffog, L; Healy, S; Sinilnikova, O M; Rennert, G; Lejbkowicz, F; Flugelman, A; Andrulis, I L; Glendon, G; Ozcelik, H; Thomassen, M; Paligo, M; Aretini, P; Kantala, J; Aroer, B; von Wachenfeldt, A; Liljegren, A; Loman, N; Herbst, K; Kristoffersson, U; Rosenquist, R; Karlsson, P; Stenmark-Askmalm, M; Melin, B; Nathanson, K L; Domchek, S M; Byrski, T; Huzarski, T; Gronwald, J; Menkiszak, J; Cybulski, C; Serrano, P; Osorio, A; Cajal, T R; Tsitlaidou, M; Benítez, J; Gilbert, M; Rookus, M; Aalfs, C M; Kluijt, I; Boessenkool-Pape, J L; Meijers-Heijboer, H E J; Oosterwijk, J C; van Asperen, C J; Blok, M J; Nelen, M R; van den Ouweland, A M W; Seynaeve, C; van der Luijt, R B; Devilee, P; Easton, D F; Peock, S; Frost, D; Platte, R; Ellis, S D; Fineberg, E; Evans, D G; Lalloo, F; Eeles, R; Jacobs, C; Adlard, J; Davidson, R; Eccles, D; Cole, T; Cook, J; Godwin, A; Bove, B; Stoppa-Lyonnet, D; Caux-Moncoutier, V; Belotti, M; Tirapo, C; Mazoyer, S; Barjhoux, L; Boutry-Kryza, N; Pujol, P; Coupier, I; Peyrat, J-P; Vennin, P; Muller, D; Fricker, J-P; Venat-Bouvet, L; Jóhannsson, Óskar Þór; Isaacs, C; Schmutzler, R; Wappenschmidt, B; Meindl, A; Arnold, N; Varon-Mateeva, R; Niederacher, D; Sutter, C; Deissler, H; Preisler-Adams, S; Simard, J; Soucy, P; Durocher, F; Chenevix-Trench, G; Beesley, J; Chen, X; Rebbeck, T; Couch, F; Wang, X; Lindor, N; Fredericksen, Z; Pankratz, V S; Peterlongo, P; Bonanni, B; Fortuzzi, S; Peissel, B; Szabo, C; Mai, P L; Loud, J T; Lubinski, J (2012-06-05)
    The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that other genetic or environmental factors modify breast cancer risk. Two genes of special interest are prohibitin (PHB) and methylene-tetrahydrofolate reductase (MTHFR), ...
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    Autoimmunity, Infections, and the Risk of Monoclonal Gammopathy of Undetermined Significance 
    Sigurbergsdóttir, Aðalbjörg Ýr; Löve, Þorvarður Jón; Kristinsson, Sigurður Yngvi (2022-04-28)
    Various epidemiological studies, including case reports and -series in addition to larger, population-based studies, have reported an increased prevalence of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma in individuals ...
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    Defining new reference intervals for serum free light chains in individuals with chronic kidney disease : Results of the iStopMM study 
    Long, Þórir Einarsson; Indriðason, Ólafur Skúli; Pálsson, Runólfur; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Thorsteinsdóttir, Sigrún; Sverrisdóttir, Ingigerður S; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Thordardottir, Asdis Rosa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Gíslason, Gauti Kjartan; Ólafsson, Andri; Steingrímsdóttir, Hlíf; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2022-09-14)
    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 ...
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    Diabetes mellitus and risk of plasma cell and lymphoproliferative disorders in 94,579 cases and 368,348 matched controls 
    Shah, Urvi A.; Rögnvaldsson, Sæmundur; Derkach, Andriy; Björkholm, Magnus; Turesson, Ingemar; David, Yael; Hultcrantz, Malin; Tan, Carlyn; Hassoun, Hani; Korde, Neha; Lesokhin, Alexander; Mailankody, Sham; Kristinsson, Sigurður Yngvi; Ola Landgren, C. (2022-01-01)
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    Educational courses on non-pharmacologic complementary interventions for nurses across Europe : The INES mapping pilot study 
    van der Heijden, Marianne J.E.; Busch, Martine; Gunnarsdottir, Thora Jenny; Lunde, Anita; Falkenberg, Torkel; van Dijk, Monique (2022-09-01)
    Background: Pharmacological interventions still form the mainstay of the management of pain, anxiety, sleep problems and discomfort. In Europe, an estimated 100 million people use complementary non-pharmacological interventions (NPIs) for these conditions. ...
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    Erratum to : Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (Nature Communications, (2018), 9, 1, (3707), 10.1038/s41467-018-04989-w) 
    The PRACTICAL consortium; Thorsteinsdottir, Unnur (2019-12-01)
    The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected in both the PDF and HTML versions ...
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    Fractures and survival in multiple myeloma : results from a population-based study 
    Thorsteinsdottir, Sigrun; Gislason, Gauti; Aspelund, Thor; Sverrisdottir, Ingigerdur; Landgren, Ola; Turesson, Ingemar; Björkholm, Magnus; Kristinsson, Sigurður Yngvi (2020-04-01)
    Multiple myeloma causes lytic bone lesions and fractures. The impact of fractures on multiple myeloma (MM) survival is unclear. The aim of this study was to evaluate the effect of fractures on survival in MM using data from MM patients diagnosed in ...
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    A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma 
    Liu, Xiaoyan; Swen, Jesse J.; Diekstra, Meta H.M.; Boven, Epie; Castellano, Daniel; Gelderblom, Hans; Mathijssen, Ron H.J.; Vermeulen, Sita H.; Oosterwijk, Egbert; Junker, Kerstin; Roessler, Max; Alexiusdottir, Kristin; Sverrisdóttir, Ásgerður; Radu, Marius T.; Ambert, Valentin; Eisen, Tim; Warren, Anne; Rodríguez-Antona, Cristina; García-Donas, Jesus; Böhringer, Stefan; Koudijs, Karel K.M.; Kiemeney, Lambertus A.L.M.; Rini, Brian I.; Guchelaar, Henk-Jan (2018-05-15)
    Purpose: The survival of patients with clear cell metastatic renal cell carcinoma (cc-mRCC) has improved substantially since the introduction of tyrosine kinase inhibitors (TKI). With the fact that TKIs interact with immune responses, we investigated ...
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    The half-painted picture: Reviewing the mental health impacts of cancer screening 
    Wadsworth, Lauren P.; Wessman, Inga Dröfn; Björnsson, Andri Steinþór; Jónsdóttir, Guðbjörg; Kristinsson, Sigurður Yngvi (2022-09-23)
    Cancer screening is recommended for select cancers worldwide. Cancer screening has become increasingly effective and accessible and often increases overall survival. However, the mental health effects of cancer screening, such as its impact on depression, ...
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    Hsa-miR-21-3p associates with breast cancer patient survival and targets genes in tumor suppressive pathways 
    Amirfallah, Arsalan; Knutsdottir, Hildur; Arason, Aðalgeir; Hilmarsdóttir, Bylgja; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardottir, Rosa B.; Reynisdottir, Inga (2021-11-19)
    Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to be an oncomiR in most cancer types, including breast cancer. Most of the effects ...
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    Iceland screens, treats, or prevents multiple myeloma (iStopMM) : a population-based screening study for monoclonal gammopathy of undetermined significance and randomized controlled trial of follow-up strategies 
    Rögnvaldsson, Sæmundur; Love, Thorvardur Jon; Thorsteinsdottir, Sigrun; Reed, Elín Ruth; Óskarsson, Jón Þórir; Pétursdóttir, Íris; Sigurðardóttir, Guðrún Ásta; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni A.; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Þórðardóttir, Ásdís Rósa; Eyþórsson, Elías; Jónsson, Ásbjörn; Björnsson, Andri S.; Gunnarsson, Gunnar Þór; Pálsson, Runólfur; Indriðason, Ólafur Skúli; Gíslason, Gauti Kjartan; Ólafsson, Andri; Hákonardóttir, Guðlaug Katrín; Brinkhuis, Manje; Halldórsdóttir, Sara Lovísa; Ásgeirsdóttir, Tinna Laufey; Steingrímsdóttir, Hlíf; Danielsen, Ragnar; Dröfn Wessman, Inga; Kampanis, Petros; Hulcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2021-05-17)
    Monoclonal gammopathy of undetermined significance (MGUS) precedes multiple myeloma (MM). Population-based screening for MGUS could identify candidates for early treatment in MM. Here we describe the Iceland Screens, Treats, or Prevents Multiple Myeloma ...
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    Illness severity and risk of mental morbidities among patients recovering from COVID-19 : A cross-sectional study in the Icelandic population 
    Saevarsdóttir, Karen Sól; Hilmarsdóttir, Hildur Ýr; Magnúsdóttir, Ingibjörg; Hauksdóttir, Arna; Thordardottir, Edda Bjork; Gudjónsdóttir, Ásdís Braga; Tomasson, Gunnar; Rúnarsdóttir, Harpa; Jónsdóttir, Harpa Lind; Gudmundsdóttir, Berglind; Pétursdóttir, Gudrún; Petersen, Pétur Henry; Kristinsson, Sigurdur Yngvi; Love, Thorvardur Jon; Hansdóttir, Sif; Hardardóttir, Hrönn; Gudmundsson, Gunnar; Eythorsson, Elias; Gudmundsdóttir, Dóra Gudrún; Sigbjörnsdóttir, Hildur; Haraldsdóttir, Sigrídur; Möller, Alma Dagbjört; Palsson, Runolfur; Jakobsdóttir, Jóhanna; Aspelund, Thor; Valdimarsdottir, Unnur (2021-07-23)
    Objective To test if patients recovering from COVID-19 are at increased risk of mental morbidities and to what extent such risk is exacerbated by illness severity. Design Population-based cross-sectional study. Setting Iceland. Participants A total of ...
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    Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life : the research protocol of the iLIVE study 
    Yildiz, Berivan; Allan, Simon; Bakan, Misa; Barnestein-Fonseca, Pilar; Berger, Michael; Boughey, Mark; Christen, Andri; De Simone, Gustavo G.; Egloff, Martina; Ellershaw, John; Elsten, Eline E.C.M.; Eychmüller, Steffen; Fischer, Claudia; Fürst, Carl Johan; Geijteman, Eric C.T.; Goldraij, Gabriel; Goossensen, Anne; Hálfdánardóttir, Svandís Íris; Haugen, Dagny Faksvåg; Hedman, Christel; Hoppe, Tanja; Hughes, Rosemary; Iversen, Grethe Skorpen; Joshi, Melanie; Kodba-Ceh, Hana; Korfage, Ida J.; Lunder, Urska; Lüthi, Nora; Martín-Roselló, Maria Luisa; Mason, Stephen; Mcglinchey, Tamsin; Montilla, Silvi; Rasmussen, Birgit H.; Ruiz-Torreras, Inmaculada; Schelin, Maria E.C.; Sigurdardottir, Katrin Ruth; Sigurdardottir, Valgerdur; Simon, Judith; Smeding, Ruthmarijke; Solvåg, Kjersti; Strupp, Julia; Tripodoro, Vilma; Van Der Kuy, Hugo M.; Van Der Rijt, Carin C.D.; Van Zuylen, Lia; Veloso, Verónica I.; Vibora-Martin, Eva; Voltz, Raymond; Zambrano, Sofia C.; Van Der Heide, Agnes (2022-08-01)
    Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to contribute to high-quality ...
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    Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders : an International Myeloma Working Group Mass Spectrometry Committee Report 
    Murray, David L.; Puig, Noemi; Kristinsson, Sigurður Yngvi; Usmani, Saad Z.; Dispenzieri, Angela; Bianchi, Giada; Kumar, Shaji; Chng, Wee Joo; Hajek, Roman; Paiva, Bruno; Waage, Anders; Rajkumar, S. Vincent; Durie, Brian (2021-02-01)
    Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect and isotype M-proteins. Increasing ...
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    Monoclonal gammopathy of undetermined significance and COVID-19 : a population-based cohort study 
    Rögnvaldsson, Sæmundur; Eythorsson, Elias; Thorsteinsdottir, Sigrun; Vidarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurdardottir, Margret; Thorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Runólfsdóttir, Hrafnhildur L.; Helgason, Dadi; Emilsdóttir, Arna Rut; Ágústsson, Arnar Snær; Björnsson, Aron Hjalti; Kristjánsdóttir, Gudrún; Thordardottir, Asdis Rosa; Indridason, Olafur Skuli; Jónsson, Ásbjörn; Gislason, Gauti Kjartan; Olafsson, Andri; Steingrímsdóttir, Hlíf; Kampanis, Petros; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Palsson, Runolfur; Love, Thorvarður Jon; Kristinsson, Sigurdur Yngvi (2021-12-01)
    Multiple myeloma (MM) patients have increased risk of severe coronavirus disease 2019 (COVID-19) when infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Monoclonal gammopathy of undetermined significance (MGUS), the precursor of ...
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    Peripheral neuropathy and monoclonal gammopathy of undetermined significance : A population-based study including 15,351 cases and 58,619 matched controls 
    Rögnvaldsson, Sæmundur; Steingrímsson, Vilhjálmur; Turesson, Ingemar; Björkholm, Magnus; Landgren, Ola; Kristinsson, Sigurður Yngvi (2020-11)
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    What are nursing students taught about complementary therapies and integrative nursing? A literature review 
    Gunnarsdottir, Þóra Jenný; van der Heijden, Marianne J.E.; Busch, Martine; Falkenberg, Torkel; Hansen, Thomas; van Dijk, Monique; Lunde, Anita (2022-06-01)
    Introduction: In Europe, more and more people use complementary therapies (CT) for the management of pain, anxiety, sleep problems and discomfort. However, nursing students are generally not taught about CT. Furthermore, nurses are not taught how to ...