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    On predicting time to completion for the first stage of spontaneous labor at term in multiparous women 
    Gunnarsson, Björn; Skogvoll, Eirik; Røislien, Jo; Smárason, Alexander Kristinn; Jónsdóttir, Ingibjörg Hanna (2017-06-12)
    Background Labor that progresses faster than anticipated may lead to unplanned out-of-hospital births. With the aim to improve planning of transportation to birthing institutions, this study investigated predictors of time to completion for the first ...
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    Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans 
    van Keulen, Danielle; Pouwer, Marianne G.; Emilsson, Valur; Matic, Ljubica Perisic; Pieterman, Elsbet J.; Hedin, Ulf; Gudnason, Vilmundur; Jennings, Lori L.; Holmstrøm, Kim; Nielsen, Boye Schnack; Pasterkamp, Gerard; Lindeman, Jan H.N.; van Gool, Alain J.; Sollewijn Gelpke, Maarten D.; Princen, Hans M.G.; Tempel, Dennie (2019-08-01)
    Objective Previous studies indicate a role for Oncostatin M (OSM) in atherosclerosis and other chronic inflammatory diseases for which inhibitory antibodies are in development. However, to date no intervention studies with OSM have been performed, and ...
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    Opinion on the impact of non-monotonic dose responses on EFSA′s human health risk assessments 
    EFSA Scientific Committee (2021-10-01)
    This Opinion assesses the biological relevance of the non-monotonic dose responses (NMDR) identified in a previous EFSA External Report (Beausoleil et al., 2016) produced under GP/EFSA/SCER/2014/01 and the follow-up probabilistic assessment (Chevillotte ...
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    Opioids for Treatment of Pre-hospital Acute Pain : A Systematic Review 
    Friesgaard, Kristian Dahl; Vist, Gunn Elisabeth; Hyldmo, Per Kristian; Raatiniemi, Lasse; Kurola, Jouni; Larsen, Robert; Kongstad, Poul; Magnússon, Viðar; Sandberg, Mårten; Rehn, Marius; Rognås, Leif (2022-01-18)
    Introduction: Acute pain is a frequent symptom among patients in the pre-hospital setting, and opioids are the most widely used class of drugs for the relief of pain in these patients. However, the evidence base for opioid use in this setting appears ...
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    Optic Nerve Subarachnoid Space Posture Dependency - An MRI Study in Subjects With Normal Tension Glaucoma and Healthy Controls 
    Kristiansen, Martin; Holmlund, Petter; Lindén, Christina; Eklund, Anders; Jóhannesson, Gauti (2023-12-01)
    PURPOSE: The purpose of this study was to examine the differences of optic nerve subarachnoid space (ONSAS) volume in patients with normal tension glaucoma (NTG) and healthy controls in different body positions. METHODS: Eight patients with NTG and ...
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    Optimal communication associated with lower risk of acute traumatic stress after lung cancer diagnosis 
    Harðardóttir, Hrönn; Aspelund, Thor; Zhu, Jianwei; Fall, Katja; Hauksdóttir, Arna; Fang, Fang; Lu, Donghao; Janson, Christer; Jónsson, Steinn; Valdimarsdóttir, Heiðdís; Valdimarsdóttir, Unnur Anna; Hardardottir, Hronn (2022-01)
    Purpose: The aim of this study was to assess the role of the patient’s background and perceived healthcare-related factors in symptoms of acute stress after lung cancer diagnosis. Methods: The study population consisted of 89 individuals referred for ...
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    Optimization and validation of a UPLC-MS/MS assay for simultaneous quantification of 2,8-dihydroxyadenine, adenine, allopurinol, oxypurinol and febuxostat in human plasma 
    Thorsteinsdottir, Unnur A; Runólfsdóttir, Hrafnhildur L.; Eiríksson, Finnur Freyr; Ágústsd., Inger María Schweitz; Eðvarðsson, Viðar Örn; Pálsson, Runólfur; Þorsteinsdóttir, Margrét (2024-03-01)
    Adenine phosphoribosyltransferase (APRT) deficiency is a rare , hereditary disorder characterized by renal excretion of 2,8-dihydroxyadenine (DHA), leading to kidney stone formation and chronic kidney disease (CKD). Treatment with a xanthine oxidoreductase ...
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    Optimizing pharmacotherapy and deprescribing strategies in older adults living with multimorbidity and polypharmacy : EuGMS SIG on pharmacology position paper 
    EuGMS SIG Pharmacology (2023-12)
    Inappropriate polypharmacy is highly prevalent among older adults and presents a significant healthcare concern. Conducting medication reviews and implementing deprescribing strategies in multimorbid older adults with polypharmacy are an inherently ...
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    Orbital Plasmacytoma in an Elderly Patient With Multiple Myeloma 
    Aloui, Salma; Qureshi, Pir Abdul Ahad Aziz; Bollineni, Vikram Rao (2024-02)
    Orbital plasmacytomas are exceedingly rare neoplasms characterized by the proliferation of monoclonal plasma cells in the orbital soft tissues. Their presentation and clinical course can be diverse, making early diagnosis and management challenging. ...
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    Orsakir búferlaflutninga fyrir og eftir bankahrun 
    Karlsson, Vífill (2013-08-05)
    Ýmsir hafa haft áhyggjur af stöðugum straumi fólks frá landsbyggð til höfuðborgar. Ýmislegt hefur verið gert á vegum opinberra aðila til að draga úr straumnum, en með litlum árangri. Vísbendingar eru um að búferlaflutningar hafi breyst á Vesturlandi, ...
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    Other-initiated repair in Icelandic 
    Gísladóttir, Rósa Signý (2015-01)
    The ability to repair problems with hearing or understanding in conversation is critical for successful communication. This article describes the linguistic practices of other-initiated repair (OIR) in Icelandic through quantitative and qualitative ...
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    Outcome After Surgery for Acute Type A Aortic Dissection With or Without Primary Tear Resection 
    Uimonen, Mikko; Olsson, Christian; Jeppsson, Anders; Geirsson, Arnar; Chemtob, Raphaelle; Khalil, Ahmad; Hjortdal, Vibeke; Hansson, Emma C.; Nozohoor, Shahab; Zindovic, Igor; Gunn, Jarmo; Wickbom, Anders; Ahlsson, Anders; Guðbjartsson, Tómas; Mennander, Ari (2022-08-01)
    Background: The outcome in patients after surgery for acute type A aortic dissection without replacement of the part of the aorta containing the primary tear is undefined. Methods: Data of 1122 patients who underwent surgery for acute type A aortic ...
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    Outsourcing of human resources : The case of small- and medium-sized enterprises 
    Eðvarðsson, Ingi Rúnar; Óskarsson, Guðmundur Kristján (2021-05-20)
    The outsourcing of human resources has increased in recent years. As in other fields of management research, limited knowledge is available on outsourcing in small- and medium-sized enterprises (SMEs). The aim of this paper is to present a study on the ...
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    Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2 
    AOCS Group; CZECANCA Consortium; The Consortium of Investigators of Modifiers of BRCA1/2; Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium; HEBON Investigators; GEMO Study Collaborators (2023-06)
    Background: The distribution of ovarian tumour characteristics differs between germline BRCA1 and BRCA2 pathogenic variant carriers and non-carriers. In this study, we assessed the utility of ovarian tumour characteristics as predictors of BRCA1 and ...
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    Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer 
    OlympiA Clinical Trial Steering Committee and Investigators (2022-12-01)
    Background: The randomized, double-blind OlympiA trial compared 1 year of the oral poly(adenosine diphosphate-ribose) polymerase inhibitor, olaparib, to matching placebo as adjuvant therapy for patients with pathogenic or likely pathogenic variants in ...
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    Overestimation of school-based deworming coverage resulting from school-based reporting 
    Sheahan, William; Anderson, Roy; Aruldas, Kumudha; Avokpaho, Euripide; Galagan, Sean; Goodman, Jeanne; Houngbegnon, Parfait; Israel, Gideon John; Janagaraj, Venkateshprabhu; Kaliappan, Saravanakumar Puthupalayam; Means, Arianna Rubin; Morozoff, Chloe; Pearman, Emily; Ramesh, Rohan Michael; Roll, Amy; Schaefer, Alexandra; Simwanza, James; Witek-Mcmanus, Stefan; Ajjampur, Sitara S.R.; Bailey, Robin; Ibikounlé, Moudachirou; Kalua, Khumbo; Luty, Adrian J.F.; Pullan, Rachel; Walson, Judd L.; Ásbjörnsdóttir, Kristjana Hrönn (2023-04-10)
    BACKGROUND: Soil Transmitted Helminths (STH) infect over 1.5 billion people globally and are associated with anemia and stunting, resulting in an annual toll of 1.9 million Disability-Adjusted Life Years (DALYs). School-based deworming (SBD), via mass ...
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    Overview of Nutrition Care in Geriatrics and Orthogeriatrics 
    Geirsdóttir, Ólöf Guðný; Bell, Jack J; Hertz, Karen; Santy-Tomlinson, Julie; Johansen, Antony (Springer Nature, 2021)
    Engaging older adults, and all those who care for them, is pivotal to providing high-value nutrition care for older adults. Nurses and other interdisciplinary team members are essential to this process. The aim of this chapter is to provide an overview ...
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    O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes 
    Barkovskaya, Anna; Seip, Kotryna; Hilmarsdóttir, Bylgja; Maelandsmo, Gunhild M; Moestue, Siver A; Itkonen, Harri M (2019-04-05)
    Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the enzyme that catalyzes ...
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    Ólögmæt dreifing örvandi lyfseðilsskyldra lyfja meðal unglinga í 10. bekk 
    Kristófersson, Gísli Kort; Arnarsson, Ársæll Már; Heimisson, Guðmundur Torfi; Sigurðardóttir, Dagbjörg (2017-12-06)
    Inngangur: Athyglisbrestur og ofvirkni (ADHD) er taugaþroskaröskun sem kemur yfirleitt fram fyrir 7 ára aldur. Örvandi lyf eru mikið notuð til meðhöndlunar á þessum kvilla hér á landi, en fela í sér hættu á ávanabindingu, misnotkun og lyfjaflakki, það ...
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    Ópíóíðaeitrun í kjölfar vórikónazólmeðferðar - sjúkratilfelli 
    Ingason, Arnar Bragi; Magnússon, Magnús Karl; Ragnarsson, Gunnar Bjarni (2019-08)
    67 ára gömul kona, sem tók langverkandi ópíóíðalyf (oxýkódon) vegna langvarandi brjóstverkja, varð fyrir bráðri ópíóíðaeitrun eftir að hafin var meðferð með vórikónazóli. Vórikónazól er sveppalyf sem getur bælt virkni CYP3A4 sem er niðurbrotsensím í ...