dc.contributor |
Háskóli Íslands |
dc.contributor |
University of Iceland |
dc.contributor.author |
Flexeder, Claudia |
dc.contributor.author |
Zock, Jan-Paul |
dc.contributor.author |
Jarvis, Deborah |
dc.contributor.author |
Verlato, Giuseppe |
dc.contributor.author |
Olivieri, Mario |
dc.contributor.author |
Benke, Geza |
dc.contributor.author |
Abramson, Michael J. |
dc.contributor.author |
Sigsgaard, Torben |
dc.contributor.author |
Svanes, Cecilie |
dc.contributor.author |
Torén, Kjell |
dc.contributor.author |
Nowak, Dennis |
dc.contributor.author |
Jõgi, Rain |
dc.contributor.author |
Martinez-Moratalla, Jesús |
dc.contributor.author |
Demoly, Pascal |
dc.contributor.author |
Janson, Christer |
dc.contributor.author |
Gislason, Thorarinn |
dc.contributor.author |
Bono, Roberto |
dc.contributor.author |
Holm, Mathias |
dc.contributor.author |
Franklin, Karl A. |
dc.contributor.author |
Garcia-Aymerich, Judith |
dc.contributor.author |
Siroux, Valérie |
dc.contributor.author |
Leynaert, Bénédicte |
dc.contributor.author |
Dorado Arenas, Sandra |
dc.contributor.author |
Corsico, Angelo Guido |
dc.contributor.author |
Pereira-Vega, Antonio |
dc.contributor.author |
Probst-Hensch, Nicole |
dc.contributor.author |
Urrutia Landa, Isabel |
dc.contributor.author |
Schulz, Holger |
dc.contributor.author |
Heinrich, Joachim |
dc.date.accessioned |
2020-05-15T14:29:40Z |
dc.date.available |
2020-05-15T14:29:40Z |
dc.date.issued |
2019-02-14 |
dc.identifier.citation |
Flexeder, C., Zock, J., Jarvis, D. et al. Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey. Respiratory Research 20, 33 (2019). https://doi.org/10.1186/s12931-019-0996-z |
dc.identifier.issn |
1465-993X |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/1807 |
dc.description |
Publisher's version (útgefin grein) |
dc.description.abstract |
Background: Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20 years. Methods: We used information from 3011 adults from 26 centres in 12 countries who participated in the European Community Respiratory Health Surveys I-III and were never or former smokers at all three surveys. Associations of SHS exposure with respiratory health (asthma symptom score, asthma, chronic bronchitis, COPD) were analysed using generalised linear mixed-effects models adjusted for confounding factors (including sex, age, smoking status, socioeconomic status and allergic sensitisation). Linear mixed-effects models with additional adjustment for height were used to assess the relationships between SHS exposure and lung function levels and decline. Results: Reported exposure to SHS decreased in all 26 study centres over time. The prevalence of SHS exposure was 38.7% at baseline (1990-1994) and 7.1% after the 20-year follow-up (2008-2011). On average 2.4% of the study participants were not exposed at the first, but were exposed at the third examination. An increase in SHS exposure over time was associated with doctor-diagnosed asthma (odds ratio (OR): 2.7; 95% confidence interval (95%-CI): 1.2-5.9), chronic bronchitis (OR: 4.8; 95%-CI: 1.6-15.0), asthma symptom score (count ratio (CR): 1.9; 95%-CI: 1.2-2.9) and dyspnoea (OR: 2.7; 95%-CI: 1.1-6.7) compared to never exposed to SHS. Associations between increase in SHS exposure and incidence of COPD (OR: 2.0; 95%-CI: 0.6-6.0) or lung function (β: - 49 ml; 95%-CI: -132, 35 for FEV1 and β: - 62 ml; 95%-CI: -165, 40 for FVC) were not apparent. Conclusion: Exposure to second-hand smoke may lead to respiratory symptoms, but this is not accompanied by lung function changes. |
dc.description.sponsorship |
The following grants helped to fund the local studies. Australia: Asthma Foundation of Victoria, Allen and Hanbury’s; Belgium: Belgian Science Policy Office, National Fund for Scientific Research; Estonia: Estonian Science Foundation, grant no 1088; France: Ministère de la Santé, Glaxo France, Insitut Pneumologique d’Aquitaine, Contrat de Plan Etat-Région Languedoc-Rousillon, CNMATS, CNMRT (90MR/10, 91AF/6), Ministre delegué de la santé, RNSP, France; GSF; Germany: Bundesminister für Forschung und Technologie; Italy: Ministero dell’Università e della Ricerca Scientifica e Tecnologica, CNR, Regione Veneto grant RSF n. 381/05.93; Norway: Norwegian Research Council project no. 101422/310; Spain: Fondo de Investigación Sanitaria (#91/0016–060-05/E, 92/0319 and #93/0393), Hospital General de Albacete, Hospital General Juan Ramón Jiménez, Dirección Regional de Salud Pública (Consejería de Sanidad del Principado de Asturias), CIRIT (1997 SGR 00079) and Servicio Andaluz de Salud; Sweden: The Swedish Medical Research Council, the Swedish Heart Lung Foundation, the Swedish Association against Asthma and Allergy; Switzerland: Swiss national Science Foundation grant 4026–28099; UK: National Asthma Campaign, British Lung Foundation, Department of Health, South Thames Regional Health Authority. The co-ordination of this work was supported by the European Commission |
dc.format.extent |
33 |
dc.language.iso |
en |
dc.publisher |
Springer Science and Business Media LLC |
dc.relation.ispartofseries |
Respiratory Research;20(1) |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Adults |
dc.subject |
Asthma |
dc.subject |
Bronchitis |
dc.subject |
ECRHS |
dc.subject |
Lung function |
dc.subject |
Respiratory symptoms |
dc.subject |
Smoking |
dc.subject |
Reykingar |
dc.subject |
Astmi |
dc.subject |
Lungnasjúkdómar |
dc.subject |
Öndunarfærasjúkdómar |
dc.subject |
Berkjubólga |
dc.title |
Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey |
dc.type |
info:eu-repo/semantics/article |
dcterms.license |
Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
dc.description.version |
Peer Reviewed |
dc.identifier.journal |
Respiratory Research |
dc.identifier.doi |
10.1186/s12931-019-0996-z |
dc.contributor.department |
Læknadeild (HÍ) |
dc.contributor.department |
Faculty of Medicine (UI) |
dc.contributor.school |
Heilbrigðisvísindasvið (HÍ) |
dc.contributor.school |
School of Health Sciences (UI) |