Opin vísindi

Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based Study

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dc.contributor Háskóli Íslands (HÍ)
dc.contributor University of Iceland (UI)
dc.contributor.author Pálsdóttir, Edda
dc.contributor.author Lund, Sigrún Helga
dc.contributor.author Ásgeirsson, Kristján Skúli
dc.date.accessioned 2020-01-24T13:54:31Z
dc.date.available 2020-01-24T13:54:31Z
dc.date.issued 2018-05-14
dc.identifier.citation Palsdottir, E. P., Lund, S. H. L., & Asgeirsson, K. S. A. (2018). Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based Study. Scandinavian Journal of Surgery, 107(3), 224–229. https://doi.org/10.1177/1457496918766686
dc.identifier.issn 1457-4969
dc.identifier.issn 1799-7267 (eISSN)
dc.identifier.uri https://hdl.handle.net/20.500.11815/1466
dc.description Publisher's version (útgefin grein).
dc.description.abstract Background and Aims: In Iceland, oncoplastic breast-conservation surgery has been performed since 2008. The aim of this population-based study was to assess and compare the efficacy and patient satisfaction of standard breast-conservation surgery with oncoplastic breast-conservation surgery. Materials and methods: This is a population-based, retrospective, observational cohort study on all women undergoing breast-conservation surgery in Iceland from the 1 January 2008 to 31 December 2014. A multivariate logistic regression and linear regression were performed to assess differences in outcomes and a patient satisfaction questionnaire was used to assess certain patient-related outcome measures. Results and conclusion: A total of 750 women underwent breast-conserving surgery, 665 had standard breast-conservation surgery and 85 oncoplastic breast-conservation surgery. Oncoplastic breast-conservation surgery was associated with a significantly larger mean size (2.4 cm vs 1.7 cm, p < 0.001) and weight (181.8 g vs 63.4 g, p < 0.001) of breast specimen excised when compared to standard breast-conservation surgery. After correcting for confounding factors, there was no significant difference in surgical margin involvement (odds ratio = 0.97, confidence interval = 0.44–1.97), frequency of complications (odds ratio = 1.06, confidence interval = 0.46–2.18), frequency of reoperations (odds ratio = 0.98; confidence interval = 0.50–1.81), or time to first adjuvant therapy (–0.23 days for oncoplastic breast-conservation surgery, p = 0.95). Patient satisfaction was high in both groups, although not statistically different (96% in oncoplastic breast-conservation surgery group vs 89% in the standard breast-conservation surgery group, p = 0.84). Our results show that oncoplastic breast-conservation surgery is at least as safe as standard breast-conservation surgery in selected cases and may be preferable in ductal carcinoma in situ.
dc.description.sponsorship The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The study was funded by Vísindasjóður Landspítalans (Landspítali University Hospital research fund).
dc.format.extent 224-229
dc.language.iso en
dc.publisher SAGE Publications
dc.relation.ispartofseries Scandinavian Journal of Surgery;107(3)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Breast
dc.subject Cancer
dc.subject Surgery
dc.subject Oncoplastic
dc.subject Breast conservation
dc.subject Ductal carcinoma in situ
dc.subject Population
dc.subject Brjóstaaðgerðir
dc.subject Krabbamein
dc.title Oncoplastic Breast-Conserving Surgery in Iceland: A Population-Based Study
dc.type info:eu-repo/semantics/article
dcterms.license © The Finnish Surgical Society 2018 Creative Commons Attribution Non-Commercial License
dc.description.version Peer Reviewed
dc.identifier.journal Scandinavian Journal of Surgery
dc.identifier.doi 10.1177/1457496918766686
dc.contributor.department Faculty of Medicine (UI)
dc.contributor.department Læknadeild (HÍ)
dc.contributor.school Heilbrigðisvísindasvið (HÍ)
dc.contributor.school School of Health Sciences (UI)

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