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Browsing by Subject "Cellular and Molecular Neuroscience"

Browsing by Subject "Cellular and Molecular Neuroscience"

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  • Sabaté San José, Alba; Petersen, Petur Henry (2024)
    Mast cells (MCs) are located in the meninges of the central nervous system (CNS), where they play key roles in the immune response. MC-deficient mice are advantageous in delineating the role of MCs in the immune response in vivo. In this study, we ...
  • Bressler, Jan; Davies, Gail; Smith, Albert Vernon; Saba, Yasaman; Bis, Joshua C.; Jian, Xueqiu; Hayward, Caroline; Yanek, Lisa; Smith, Jennifer A.; Mirza, Saira S.; Wang, Ruiqi; Adams, Hieab H.H.; Becker, Diane; Boerwinkle, Eric; Campbell, Archie; Cox, Simon R.; Eiríksdóttir, Guðný; Fawns-Ritchie, Chloe; Gottesman, Rebecca F.; Grove, Megan L.; Guo, Xiuqing; Hofer, Edith; Kardia, Sharon L.R.; Knol, Maria J.; Koini, Marisa; Lopez, Oscar L.; Marioni, Riccardo E.; Nyquist, Paul; Pattie, Alison; Polasek, Ozren; Porteous, David J.; Rudan, Igor; Satizabal, Claudia L.; Schmidt, Helena; Schmidt, Reinhold; Sidney, Stephen; Simino, Jeannette; Smith, Blair H.; Turner, Stephen T.; van der Lee, Sven J.; Ware, Erin B.; Whitmer, Rachel A.; Yaffe, Kristine; Yang, Qiong; Zhao, Wei; Guðnason, Vilmundur G.; Launer, Lenore J.; Fitzpatrick, Annette L.; Psaty, Bruce M.; Fornage, Myriam; Arfan Ikram, M.; van Duijn, Cornelia M.; Seshadri, Sudha; Mosley, Thomas H.; Deary, Ian J. (2021-12-04)
    Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare ...
  • Li, Yuchen; Sjölander, Arvid; Song, Huan; Cnattingius, Sven; Fang, Fang; Yang, Qian; Fernández de la Cruz, Lorena; Mataix-Cols, David; Brander, Gustaf; Li, Jiong; Zhang, Wei; Fall, Katja; D’Onofrio, Brian M.; Almqvist, Catarina; Lichtenstein, Paul; Valdimarsdóttir, Unnur Anna; Lu, Donghao (2022-01-01)
    Little is known about the contribution of pregnancy-related parental and perinatal factors to the development of stress-related disorders. We aimed to investigate whether parental/perinatal adversities entail higher risks of stress-related disorders ...
  • Holmlund, Petter; Støverud, Karen Helene; Wåhlin, Anders; Wiklund, Urban; Malm, Jan; Jóhannesson, Gauti; Eklund, Anders (2021-12)
  • Kristinsson, Sigfús Helgi; Busby, Natalie; Rorden, Christopher; Newman-Norlund, Roger; Den Ouden, Dirk B.; Magnúsdóttir, Sigríður; Hjaltason, Haukur; Thors, Helga; Hillis, Argye E.; Kjartansson, Olafur; Bonilha, Leonardo; Fridriksson, Julius (2022)
    The association between age and language recovery in stroke remains unclear. Here, we used neuroimaging data to estimate brain age, a measure of structural integrity, and examined the extent to which brain age at stroke onset is associated with (i) ...
  • Aubonnet, Romain; Hassan, M; Mheich, A; Di Lorenzo, G; Petersen, Hannes; Gargiulo, Paolo (2023-04-03)
    Objective.To decipher brain network dynamic remodeling from electroencephalography (EEG) during a complex postural control (PC) task combining virtual reality and a moving platform.Approach.EEG (64 electrodes) data from 158 healthy subjects were acquired. ...
  • Rennie, Anna; Ekman, Urban; Shams, Sara; Rydén, Lina; Samuelsson, Jessica; Zettergren, Anna; Kern, Silke; Oppedal, Ketil; Blanc, Frédéric; Hort, Jakub; Garcia-Ptacek, Sara; Antonini, Angelo; Lemstra, Afina W; Padovani, Alessandro; Kramberger, Milica Gregoric; Rektorová, Irena; Walker, Zuzana; Snædal, Jón G; Pardini, Matteo; Taylor, John-Paul; Bonanni, Laura; Granberg, Tobias; Aarsland, Dag; Skoog, Ingmar; Wahlund, Lars-Olof; Kivipelto, Miia; Westman, Eric; Ferreira, Daniel (2024-08-28)
    Co-pathologies are common in dementia with Lewy bodies and other dementia disorders. We investigated cerebrovascular and Alzheimer's disease co-pathologies in patients with dementia with Lewy bodies in comparison with patients with mild cognitive ...
  • Matthiasdottir, Anna Mjoll; Hardarson, Thorgeir Orri; Arnardottir, Steinunn; Sigurjónsdóttir, Helga Ágústa (2024-10)
    INTRODUCTION: In 2011, we reported the overall incidence of Cushing's disease (CD) in Iceland from 1955 through 2009 to be 1.5 cases per million per year with highest incidence in the last decade of the study, a higher incidence then earlier reported. ...
  • Hall, A. R.; Burke, N.; Dongworth, R. K.; Kalkhoran, Siavash Beikoghli; Dyson, A.; Vicencio, J. M.; Dorn, G. W.; Yellon, D. M.; Hausenloy, D. J. (2021-06-30)
    The original version of this article unfortunately contained a mistake in an author name. The correct author name is GW Dorn 2nd. The original article has been corrected.
  • Azuara-Blanco, Augusto; McCorry, Noleen; Tatham, Andrew J.; Georgoulas, Stelios; Founti, Panayiota; Schweitzer, Cedric; Meier-Gibbons, Frances; Denis, Philippe; Tuulonen, Anja; Johannesson, Gauti; De La Casa, José María Martínez; Prokosch, Verena; Giannoulis, Dimitrios A.; Abegão Pinto, Luis; Garway-Heath, David; Topouzis, Fotis (2023-11-03)
    Background/Aims: The goal of health research is to improve patients care and outcomes. Thus, it is essential that research addresses questions that are important to patients and clinicians. The aim of this study was to develop a list of priorities for ...
  • Lahti, Jari; Tuominen, Samuli; Yang, Qiong; Pergola, Giulio; Ahmad, Shahzad; Amin, Najaf; Armstrong, Nicola J.; Beiser, Alexa; Bey, Katharina; Bis, Joshua C.; Boerwinkle, Eric; Bressler, Jan; Campbell, Archie; Campbell, Harry; Chen, Qiang; Corley, Janie; Cox, Simon R.; Davies, Gail; De Jager, Philip L.; Derks, Eske M.; Faul, Jessica D.; Fitzpatrick, Annette L.; Fohner, Alison E.; Ford, Ian; Fornage, Myriam; Gerring, Zachary; Grabe, Hans J.; Grodstein, Francine; Gudnason, Vilmundur; Simonsick, Eleanor; Holliday, Elizabeth G.; Joshi, Peter K.; Kajantie, Eero; Kaprio, Jaakko; Karell, Pauliina; Kleineidam, Luca; Knol, Maria J.; Kochan, Nicole A.; Kwok, John B.; Leber, Markus; Lam, Max; Lee, Teresa; Li, Shuo; Loukola, Anu; Luck, Tobias; Marioni, Riccardo E.; Mather, Karen A.; Medland, Sarah; Mirza, Saira S.; Nalls, Mike A. (2022-08-16)
    Understanding the genomic basis of memory processes may help in combating neurodegenerative disorders. Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke ...
  • Capone, Emily; Tryggvason, Þórður; Cela, Ilaria; Dufrusine, Beatrice; Pinti, Morena; Del Pizzo, Francesco; Gunnarsdóttir, Helga Sigrún; Grottola, Tommaso; De Laurenzi, Vincenzo; Iacobelli, Stefano; Lattanzio, Rossano; Sala, Gianluca (2023-10-28)
    HER-3 (also known as ErbB-3) is a human epidermal growth factor receptor tyrosine kinases family member, and its expression in CRC (colorectal cancer) tissues was previously associated with poor prognosis. In this study, HER-3 expression was analyzed ...
  • Jóhannesson, Gauti; Qvarlander, Sara; Wåhlin, Anders; Ambarki, Khalid; Hallberg, Per; Eklund, Anders; Lindén, Christina (2020-10)
    PURPOSE. To investigate if decrease of IOP affects the volumetric blood flow rate in the ophthalmic artery (OA) in patients with previously untreated ocular hypertension. METHODS. Subjects with untreated ocular hypertension (n = 30; mean age 67 ± 8 ...
  • Skuladottir, Astros Th; Tragante, Vinicius; Sveinbjornsson, Gardar; Helgason, Hannes; Sturluson, Arni; Bjornsdottir, Anna; Jónsson, Pálmi V; Pálmadóttir, Vala Kolbrún; Sveinsson, Olafur A.; Jensson, Brynjar O.; Gudjonsson, Sigurjon A.; Ivarsdottir, Erna V.; Gisladottir, Rosa S.; Gunnarsson, Arni F.; Walters, G. Bragi; Jonsdottir, Gudrun A.; Thorgeirsson, Thorgeir E.; Bjornsdottir, Gyda; Holm, Hilma; Gudbjartsson, Daniel F.; Sulem, Patrick; Stefansson, Hreinn; Stefansson, Kari (2024-08-15)
    Parkinson’s disease (PD) is a debilitating neurodegenerative disorder and its rising global incidence highlights the need for the identification of modifiable risk factors. In a gene-based burden test of rare variants (8647 PD cases and 777,693 controls) ...
  • Skarphedinsdottir, Sunna Bjorg; Eysteinsson, Þór; Árnason, Sighvatur Sævar (2020-06)
    PURPOSE. To examine ion transport across the mouse retinal pigment epithelium (RPE), measured by the short-circuit current (ISC) and transepithelial resistance (TER). METHODS. Sheets of RPE from mice (C57BL6/J) with retina, choroid, and sclera attached ...
  • Eliasdottir, Olöf Jona; Kjartansson, Ólafur; Ólafsson, Elías (2023-04-01)
    Introduction: Mortality is an important feature of the natural history of multiple sclerosis (MS). We report the mortality of all individuals with MS in Iceland, identified in a nationwide population-based study. Patients and Methods: The results are ...
  • Hanna, Sebastian; Pálmadóttir, Vala Kolbrún; Penar, Paul L; Boyd, James T (2023-01)
    Neuropsychiatric adverse events have been previously reported following deep brain stimulation (DBS) for Parkinson's disease (PD). Most cases described have involved DBS of the subthalamic nucleus (STN). We report a unique case of acute-onset and ...
  • Hu, Yi Han; Meirelles, Osorio; Shiroma, Eric J.; Satizabal, Claudia L.; Seshadri, Sudha; Tracy, Russell P.; Gudnason, Vilmundur; Launer, Lenore J. (2024-12)
    INTRODUCTION: Peripheral risk factors (PRFs) may correlate with dementia plasma biomarkers, potentially reflecting peripheral rather than brain health. This study explores the associations between PRFs and plasma biomarkers glial fibrillary acidic ...
  • Holmlund, Petter; Støverud, Karen Helene; Wåhlin, Anders; Wiklund, Urban; Malm, Jan; Jóhannesson, Gauti; Eklund, Anders (2021-04)
    Purpose: We hypothesize that a collapse of the optic nerve subarachnoid space (ONSAS) in the upright posture may protect the eyes from large translamina cribrosa pressure differences (TLCPD) believed to play a role in various optic nerve diseases (e.g., ...
  • Hugosdottir, Rosa; Mørch, Carsten Dahl; Andersen, Ole Kæseler; Helgason, Thordur; Arendt-Nielsen, Lars (Springer Science and Business Media LLC, 2019-09-14)
    Background Electrical stimulation is widely used in experimental pain research but it lacks selectivity towards small nociceptive fibers. When using standard surface patch electrodes and rectangular pulses, large fibers are activated at a lower threshold ...