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Browsing by Subject "Biomarkers"
Now showing items 1-20 of 29
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(MDPI AG, 2019-03-06)The growing interest in potential health effects of long-chain polyunsaturated fatty acids (PUFAs) makes it important to evaluate the method used to assess the fatty acid intake in nutrition research studies. We aimed to validate the questionnaire-based ... -
(2022-03-16)Antibody-mediated rejection is a common cause of early kidney allograft loss but the specifics of antibody measurement, therapies and endpoints have not been universally defined. In this retrospective study, we assessed the performance of risk ...
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(2023-03)Estimation of kidney function is often part of daily clinical practice, mostly done by using the endogenous glomerular filtration rate (GFR)-markers creatinine or cystatin C. A recommendation to use both markers in parallel in 2010 has resulted in new ...
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(2024-03-15)There is a growing interest for the possibility of using peripheral blood cells (including platelets) as markers for mitochondrial function in less accessible tissues. Only a few studies have examined the correlation between respiration in blood and ...
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(Springer Science and Business Media LLC, 2020-08-10)Background: Culicoides hypersensitivity (CH) is induced in horses by salivary allergens of Culicoides midges. In Iceland, the causal Culicoides species for CH are not present. Previous epidemiological data indicated that Icelandic horses are more ...
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(2021-06-02)Soluble urokinase-type plasminogen activator receptor (suPAR) is a chronic inflammation marker associated with the development of a range of diseases, including cancer and cardiovascular disease. The genetics of suPAR remain unexplored but may shed ...
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(2019-07-01)Galectins regulate cell growth, proliferation, differentiation, apoptosis, signal transduction, mRNA splicing, and interactions with the extracellular matrix. Here we focus on the galectins in the reproductive system, particularly on a group of six ...
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A genome-wide association study identifies genetic loci associated with specific lobar brain volumes (Springer Science and Business Media LLC, 2019-08-02)Brain lobar volumes are heritable but genetic studies are limited. We performed genome-wide association studies of frontal, occipital, parietal and temporal lobe volumes in 16,016 individuals, and replicated our findings in 8,789 individuals. We ...
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(2019-05-14)INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
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(2023-04)As one of the core elements of the European Human Biomonitoring Initiative (HBM4EU) a human biomonitoring (HBM) survey was conducted in 23 countries to generate EU-wide comparable HBM data. This survey has built on existing HBM capacity in Europe by ...
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(Elsevier BV, 2020-07-15)Arctic precipitation is predicted to increase in the coming century, due to a combination of enhanced northward atmospheric moisture transport and local surface evaporation from ice-free seas. However, large model uncertainties, limited long-term ...
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(Springer Science and Business Media LLC, 2019-06-11)Epigenetic processes, including DNA methylation (DNAm), are among the mechanisms allowing integration of genetic and environmental factors to shape cellular function. While many studies have investigated either environmental or genetic contributions ...
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Lífefni í mænuvökva nýbura: forspárgildi fyrir heilaskaða. Tengsl við lifun og röskun á taugaþroska (University of Iceland, School of Health Sciences, Faculty of Medicine, 2022-06)Bakgrunnur Ágrip Börn sem verða fyrir súrefnisskorti í fæðingu og börn sem fæðast fyrir fulla meðgöngu eiga á hættu að lifa ekki af eða hljóta varanlegan heilaskaða. Hættan á þessum fylgikvillum hefur ekki minnkað á síðustu áratugum þrátt fyrir miklar ...
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(2022-07-29)Objectives: All SARS-CoV-2-positive persons in Iceland were prospectively monitored and those who required outpatient evaluation or were admitted to hospital underwent protocolized evaluation that included a standardized panel of biomarkers. The aim ...
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(MDPI AG, 2019-09-18)One of the main objectives for astrobiology is to unravel and explore the habitability of environments beyond Earth, paying special attention to Mars. If the combined environmental stress factors on Mars are compatible with life or if they were less ...
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(Springer Science and Business Media LLC, 2019-02-02)Background: There is insufficient knowledge of pathophysiological parameters to understand the mechanism behind prolonged whiplash associated disorders (WAD), and it is not known whether or not changes can be restored by rehabilitation. The aims of the ...
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(2023-12)Background: Recent findings from studies of mouse models of Mendelian disorders of epigenetic machinery strongly support the potential for postnatal therapies to improve neurobehavioral and cognitive deficits. As several of these therapies move into ...
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(Informa UK Limited, 2019-03-27)Introduction: Reduced concentrations of placental protein 13 (PP13) during the first trimester of human pregnancy are associated with elevated risk for the subsequent development of preeclampsia, which is one of the deadliest obstetrical complications ...
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(2023-03-01)Emerging plasma biomarkers of Alzheimer's disease might be non-invasive tools to trace early Alzheimer's disease-related abnormalities such as the accumulation of amyloid-beta peptides, neurofibrillary tau tangles, glial activation and neurodegeneration. ...
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(Elsevier BV, 2018-09)Background: Fish oil supplementation has been shown to delay spontaneous delivery, but the levels and clinical significance remain uncertain. We examined the association between plasma fatty acids quantified in pregnancy and subsequent risk of early ...
Now showing items 1-20 of 29