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Browsing by Author "Lange, Sigrun"

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Extracellular vesicles, deiminated protein cargo and microRNAs are novel serum biomarkers for environmental rearing temperature in Atlantic cod (Gadus morhua L.)

Magnadottir, Bergljot; Uysal-Onganer, Pinar; Kraev, Igor; Dodds, Alister W.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2020-03)

Extracellular vesicles (EVs) are released from cells and carry protein and genetic cargo involved in cell communication. EVs isolated from bodyfluids, including plasma and serum, can also be used as markers of pathophysiological changes. Peptidylarginine ...
Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny

Magnadottir, Bergljot; Hayes, Polly; Gísladóttir, Berglind; Bragason, Birkir; Hristova, Mariya; Nicholas, Anthony P.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)

Pentraxins arefluid phase pattern recognition molecules that form an important part of the innate immunedefence and are conserved betweenfish and human. In Atlantic cod (Gadus morhuaL.), two pentraxin-likeproteins have been described, CRP-I and CRP-II. ...
Peptidylarginine deiminase and deiminated proteins are detected throughout early halibut ontogeny - Complement components C3 and C4 are post-translationally deiminated in halibut (Hippoglossus hippoglossus L.)

Magnadottir, Bergljot; Bragason, Birkir; Bricknell, Ian; Bowden, Timothy; Nicholas, Anthony P.; Hristova, Mariya; Guðmundsdóttir, Sigríður; Dodds, Alister W.; Lange, Sigrun (Elsevier BV, 2019-03)

Post-translational protein deimination is mediated by peptidylarginine deiminases (PADs), which are calcium dependent enzymes conserved throughout phylogeny with physiological and pathophysiological roles. Protein deimination occurs via the conversion ...
Post-translational protein deimination in cod (Gadus morhua L.) ontogeny novel roles in tissue remodelling and mucosal immune defences?

Magnadottir, Bergljot; Hayes, Polly; Hristova, Mariya; Bragason, Birkir; Nicholas, Anthony P.; Dodds, Alister W.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)

Peptidylarginine deiminases (PADs) are calcium dependent enzymes with physiological and pathophysiologicalroles conserved throughout phylogeny. PADs promote post-translational deimination of protein arginine to ci-trulline, altering the structure and ...

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Browsing by Author "Lange, Sigrun"

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