Opin vísindi

Fletta eftir höfundi "Gudbjartsson, Daniel"

Fletta eftir höfundi "Gudbjartsson, Daniel"

Röðun: Raða: Niðurstöður:

  • Ulfarsson, Magnus; Walters, G B; Gústafsson, O; Steinberg, S; Silva, A; Doyle, O M; Brammer, M; Gudbjartsson, Daniel; Arnarsdóttir, S; Jonsdottir, Gudbjorg; Gísladóttir, R S; Bjornsdottir, Gyda; Helgason, H; Ellingsen, L M; Halldórsson, J G; Sæmundsen, Evald E.; Stefánsdóttir, B; Jónsson, L; Eiríksdóttir, V K; Eiríksdóttir, G R; Jóhannesdóttir, G H; Unnsteinsdóttir, U; Jónsdóttir, B; Magnúsdóttir, B B; sulem, patrick; Þorsteinsdóttir, Unnur; Sigurðsson, E; Brandeis, D; Meyer-Lindenberg, A; Stefánsson, H; Stefánsson, Kári (Springer Nature, 2017-04-25)
    Several copy number variants have been associated with neuropsychiatric disorders and these variants have been shown to also influence cognitive abilities in carriers unaffected by psychiatric disorders. Previously, we associated the 15q11.2(BP1–BP2) ...
  • Jensson, Brynjar O.; Hansdottir, Sif; Árnadottir, Guðný A.; Sulem, Gerald; Kristjansson, Ragnar; Oddsson, Asmundur; Benónísdóttir, Stefanía; Jónsson, Hákon; Helgason, Agnar; Sæmundsdóttir, Jóna; Magnússon, Ólafur T.; Másson, Gísli; Thorisson, Gudmundur; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Jonsdottir, Ingileif; Pétursdóttir, Vigdís; Kristinsson, Jón R.; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Arngrimsson, Reynir; sulem, patrick; Guðmundsson, Gunnar; Stefánsson, Kári (Springer Nature, 2017-11-14)
    Background: Rare missense mutations in the gene encoding coatomer subunit alpha (COPA) have recently been shown to cause autoimmune interstitial lung, joint and kidney disease, also known as COPA syndrome, under a dominant mode of inheritance. Case ...
  • Ólafsson, Sigurgeir; Stridh, Pernilla; Bos, Steffan Daniël; Ingason, Andrés; Euesden, Jack; Sulem, Patrick; Thorleifsson, Gudmar; Gústafsson, Ómar; Jóhannesson, Ari; Geirsson, Árni J.; Þórsson, Árni V.; Sigurgeirsson, Bárður; Lúðvíksson, Björn Rúnar; Ólafsson, Elías; Kristjansdottir, Helga; Jónasson, Jón G.; Ólafsson, Jón Hjaltalín; Örvar, Kjartan B.; Benediktsson, Rafn; Bjarnason, Ragnar; Kristjánsdóttir, Sjöfn; Gíslason, Þórarinn; Valdimarsson, Trausti; Mikaelsdóttir, Evgenía; Sigurðsson, Snævar; Jonsson, Stefan; Rafnar, Þórunn; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Knudsen, Gun Peggy; Celius, Elisabeth G.; Myhr, Kjell-Morten; Gröndal, Gerður; Steinsson, Kristján; Valdimarsson, Helgi; Björnsson, Sigurður; Björnsdóttir, Unnur Steina; Björnsson, Einar S.; Nilsson, Bjorn; Andreassen, Ole A.; Alfredsson, Lars; Hillert, Jan; Kockum, Ingrid Skelton; Masson, Gisli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Stefansson, Hreinn; Hjaltason, Haukur; Harbo, Hanne F.; Olsson, Tomas; Jonsdottir, Ingileif; Stefánsson, Kári (Springer Nature, 2017-08-08)
    A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic multiple sclerosis cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating with multiple sclerosis, not reported ...
  • Helgadottir, Anna; Thorleifsson, Gudmar; Grétarsdóttir, Sólveig; Stefánsson, Ólafur A.; Tragante, Vinicius; Þórólfsdóttir, Rósa B.; Jonsdottir, Ingileif; Bjoönsson, Þorsteinn; Steinthorsdottir, Valgerdur; Verweij, Niek; Nielsen, Jonas B.; Zhou, Wei; Folkersen, Lasse; Martinsson, Andreas; Heydarpour, Mahyar; Prakash, Siddharth; Óskarsson, Gylfi; Guðbjartsson, Tómas; Geirsson, Arnar; Ólafsson, Ísleifur; Sigurðsson, Emil L.; Almgren, Peter; Melander, Olle; Franco-Cereceda, Anders; Hamsten, Anders; Fritsche, Lars; Lin, Maoxuan; Yang, Bo; Hornsby, Whitney; Guo, Dongchuan; Brummett, Chad M.; Abecasis, Gonçalo; Mathis, Michael; Milewicz, Dianna; Body, Simon C.; Eriksson, Per; Willer, Cristen J.; Hveem, Kristian; Newton-Cheh, Christopher; Smith, J. Gustav; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Hólm, Hilma; Stefánsson, Kári (Springer Nature, 2018-03-07)
    Aortic valve stenosis (AS) is the most common valvular heart disease, and valve replacement is the only definitive treatment. Here we report a large genome-wide association (GWA) study of 2,457 Icelandic AS cases and 349,342 controls with a follow-up ...
  • Guðmundsson, Júlíus; Þorleifsson, Guðmar; Sigurðsson, Jón K.; Stefánsdóttir, Lilja; Jónasson, Jón G.; Guðjónsson, Sigurjón Axel; Gudbjartsson, Daniel; Másson, Gísli; Jóhannsdóttir, Hrefna; Halldórsson, Gísli H.; Stacey, Simon N.; Helgason, Hannes; sulem, patrick; Senter, Leigha; He, Huiling; Liyanarachchi, Sandya; Ringel, Matthew D.; Aguillo, Esperanza; Panadero, Angeles; Prats, Enrique; Garcia-Castaño, Almudena; De Juan, Ana; Rivera, Fernando; Xu, Li; Kiemeney, Lambertus A.; Eyjólfsson, Guðmundur I.; Sigurðardóttir, Ólöf; Ólafsson, Ísleifur; Kristvinsson, Höskuldur; Netea-Maier, Romana T.; Jónsson, Þorvaldur; Mayordomo, Jose I.; Plantinga, Theo S.; Hjartarson, Hannes; Hrafnkelsson, Jón; Sturgis, Erich M.; Þorsteinsdóttir, Unnur; Rafnar, Þórunn; de la Chapelle, Albert; Stefánsson, Kári (Springer Nature, 2017-02-14)
    The great majority of thyroid cancers are of the non-medullary type. Here we report findings from a genome-wide association study of non-medullary thyroid cancer, including in total 3,001 patients and 287,550 controls from five study groups of European ...
  • Reginsson, Gunnar W.; Ingason, Andres; Euesden, Jack; Bjornsdottir, Gyda; Ólafsson, Sigurgeir; Sigurdsson, Engilbert; Óskarsson, Högni; Tyrfingsson, Þórarinn; Rúnarsdóttir, Valgerður; Hansdóttir, Ingunn; Steinberg, Stacy; Stefánsson, Hreinn; Gudbjartsson, Daniel; Thorgeirsson, Thorgeir; Stefánsson, Kári (Wiley, 2017-02-23)
    We use polygenic risk scores (PRSs) for schizophrenia (SCZ) and bipolar disorder (BPD) to predict smoking, and addiction to nicotine, alcohol or drugs in individuals not diagnosed with psychotic disorders. Using PRSs for 144 609 subjects, including 10 ...
  • Smith, Dirk; Helgason, Hannes; sulem, patrick; Björnsdóttir, Unnur Steina; Lim, Ai Ching; Sveinbjörnsson, Garðar; Hasegawa, Haruki; Brown, Michael; Ketchem, Randal R.; Gavala, Monica; Garrett, Logan; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Sigurðsson, Ásgeir; Magnússon, Ólafur T.; Eyjólfsson, Guðmundur I.; Ólafsson, Ísleifur; Önundarson, Páll Torfi; Sigurðardóttir, Ólöf; Gíslason, Davíð; Gíslason, Þórarinn; Lúðvíksson, Björn Rúnar; Lúðvíksdóttir, Dóra; Boezen, H. Marike; Heinzmann, Andrea; Krueger, Marcus; Porsbjerg, Celeste; Ahluwalia, Tarunveer S.; Waage, Johannes; Backer, Vibeke; Deichmann, Klaus A.; Koppelman, Gerard H.; Bønnelykke, Klaus; Bisgaard, Hans; Másson, Gísli; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel; Johnston, James A.; Jonsdottir, Ingileif; Stefánsson, Kári (Public Library of Science (PLoS), 2017-03-08)
    IL-33 is a tissue-derived cytokine that induces and amplifies eosinophilic inflammation and has emerged as a promising new drug target for asthma and allergic disease. Common variants at IL33 and IL1RL1, encoding the IL-33 receptor ST2, associate with ...
  • Mullins, Niamh; Ingason, Andrés; Porter, Heather; Euesden, Jack; Gillett, Alexandra; Ólafsson, Sigurgeir; Gudbjartsson, Daniel; Lewis, Cathryn M.; Sigurdsson, Engilbert; Sæmundsen, Evald E.; Guðmundsson, Ólafur Ó.; Frigge, Michael L.; Kong, Augustine; Helgason, Agnar; Walters, G. Bragi; Gústafsson, Ómar; Stefánsson, Hreinn; Stefánsson, Kári (Springer Nature, 2017-06-13)
    The persistence of common, heritable psychiatric disorders that reduce reproductive fitness is an evolutionary paradox. Here, we investigate the selection pressures on sequence variants that predispose to schizophrenia, autism, bipolar disorder, major ...
  • Kristjansson, Ragnar; Benónísdóttir, Stefanía; Oddsson, Asmundur; Galesloot, Tessel E.; Þorleifsson, Guðmar; Aben, Katja K.; Davíðsson, Ólafur B.; Jonsson, Stefan; Árnadottir, Guðný A.; Jensson, Brynjar O.; Walters, G. Bragi; Sigurðsson, Jón K.; Sigurðsson, Snævar; Hólm, Hilma; Arnar, David O.; Thorgeirsson, Gudmundur; Alexíusdóttir, Kristín; Jonsdottir, Ingileif; Thorsteinsdottir, Unnur; Kiemeney, Lambertus A.; Jónsson, Þorvaldur; Gudbjartsson, Daniel; Rafnar, Þórunn; sulem, patrick; Stefánsson, Kári (Springer Nature, 2017-06-08)
    Appendicitis is one of the most common conditions requiring acute surgery and can pose a threat to the lives of affected individuals. We performed a genome-wide association study of appendicitis in 7,276 Icelandic and 1,139 Dutch cases and large groups ...
  • Bjornsdottir, Gyda; Benónísdóttir, Stefanía; Sveinbjörnsson, Garðar; Styrkarsdottir, Unnur; Þorleifsson, Guðmar; Walters, G. Bragi; Björnsson, Aron; Ólafsson, Ingvar Hákon; Úlfarsson, Elfar; Víkingsson, Arnór; Hansdóttir, Ragnheiður; Karlsson, Karl O.; Rafnar, Þórunn; Jonsdottir, Ingileif; Frigge, Michael L.; Kong, Augustine; Oddsson, Asmundur; Másson, Gísli; Magnússon, Ólafur T.; Guðbjartsson, Tómas; Stefánsson, Hreinn; sulem, patrick; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Thorgeirsson, Thorgeir; Stefánsson, Kári (Springer Nature, 2017-02-22)
    Lumbar disc herniation (LDH) is common and often debilitating. Microdiscectomy of herniated lumbar discs (LDHsurg) is performed on the most severe cases to resolve the resulting sciatica. Here we perform a genome-wide association study on 4,748 LDHsurg ...
  • Jónsson, Hákon; sulem, patrick; Kehr, Birte; Kristmundsdóttir, Snædís; Zink, Florian; Hjartarson, Eiríkur; Harðarson, Marteinn T.; Hjorleifsson, Kristjan; Eggertsson, Hannes; Guðjónsson, Sigurjón Axel; Ward, Lucas D.; Arnadottir, Gudny; Helgason, Einar A.; Helgason, Hannes; Gylfason, Arnaldur; Jónasdóttir, Aðalbjörg; Jónasdóttir, Áslaug; Rafnar, Þórunn; Besenbacher, Soren; Frigge, Michael L.; Stacey, Simon N.; Magnússon, Ólafur T.; Þorsteinsdóttir, Unnur; Másson, Gísli; Kong, Augustine; Halldórsson, Bjarni; Helgason, Agnar; Gudbjartsson, Daniel; Stefánsson, Kári (Springer Nature, 2017-09-21)
    Understanding of sequence diversity is the cornerstone of analysis of genetic disorders, population genetics, and evolutionary biology. Here, we present an update of our sequencing set to 15,220 Icelanders who we sequenced to an average genome-wide ...