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Browsing by Author "Aspelund, Thor"

Browsing by Author "Aspelund, Thor"

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    1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function 
    Gorski, Mathias; van der Most, Peter J.; Teumer, Alexander; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Nolte, Ilja M.; Cocca, Massimiliano; Taliun, Daniel; Gomez, Felicia; Li, Yong; Tayo, Bamidele; Tin, Adrienne; Feitosa, Mary F.; Aspelund, Thor; Attia, John; Biffar, Reiner; Bochud, Murielle; Boerwinkle, Eric; Borecki, Ingrid; Bottinger, Erwin P.; Chen, Ming-Huei; Chouraki, Vincent; Ciullo, Marina; Coresh, Josef; Cornelis, Marilyn C.; Curhan, Gary C.; d’Adamo, Adamo Pio; Dehghan, Abbas; Dengler, Laura; Ding, Jingzhong; Eiríksdóttir, Guðný; Endlich, Karlhans; Enroth, Stefan; Esko, Tõnu; Franco, Oscar H.; Gasparini, Paolo; Gieger, Christian; Girotto, Giorgia; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Hancock, Stephen J.; Harris, Tamara B.; Helmer, Catherine; Höllerer, Simon; Hofer, Edith; Hofman, Albert; Holliday, Elizabeth G.; Homuth, Georg; Hu, Frank B.; Huth, Cornelia; Hutri-Kähönen, Nina; Hwang, Shih-Jen; Imboden, Medea; Johansson, Åsa; Kähönen, Mika; König, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kumar, Ashish; Kutalik, Zoltán; Lambert, Jean-Charles; Launer, Lenore J.; Lehtimäki, Terho; de Borst, Martin; Navis, Gerjan; Swertz, Morris; Liu, Yongmei; Lohman, Kurt; Loos, Ruth J. F.; Lu, Yingchang; Lyytikäinen, Leo-Pekka; McEvoy, Mark A.; Meisinger, Christa; Meitinger, Thomas; Metspalu, Andres; Metzger, Marie; Mihailov, Evelin; Mitchell, Paul; Nauck, Matthias; Oldehinkel, Albertine J.; Olden, Matthias; WJH Penninx, Brenda; Pistis, Giorgio; Pramstaller, Peter P.; Probst-Hensch, Nicole; Raitakari, Olli T.; Rettig, Rainer; Ridker, Paul M.; Rivadeneira, Fernando; Robino, Antonietta; Rosas, Sylvia E.; Ruderfer, Douglas; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia; Schmidt, Helena; Schmidt, Reinhold; Scott, Rodney J.; Sedaghat, Sanaz; Smith, Albert Vernon; Sorice, Rossella; Stengel, Benedicte; Stracke, Sylvia; Strauch, Konstantin; Toniolo, Daniela; Uitterlinden, André G.; Ulivi, Sheila; Viikari, Jorma S.; Völker, Uwe; Vollenweider, Peter; Völzke, Henry; Vuckovic, Dragana; Waldenberger, Melanie; Jin Wang, Jie; Yang, Qiong; Chasman, Daniel I.; Tromp, Gerard; Snieder, Harold; Heid, Iris M.; Fox, Caroline S.; Köttgen, Anna; Pattaro, Cristian; Böger, Carsten A.; Fuchsberger, Christian (Springer Nature, 2017-04-28)
    HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation, such as those from The ...
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    ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19 
    Emilsson, Valur; Gudmundsson, Elias F; Aspelund, Thor; Jonsson, Brynjolfur G; Gudjonsson, Alexander; Launer, Lenore J.; Lamb, John R; Gudmundsdottir, Valborg; Jennings, Lori L; Gudnason, Vilmundur (2020-06-05)
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    Adverse childhood experiences and psychological functioning among women with schizophrenia or bipolar disorder : population-based study 
    Köhler-Forsberg, Ole; Ge, Fenfen; Hauksdóttir, Arna; Þórðardóttir, Edda Björk; Ásbjörnsdóttir, Kristjana Hrönn; Rúnarsdóttir, Harpa; Tómasson, Gunnar; Jakobsdóttir, Jóhanna; Guðmundsdóttir, Berglind; Björnsson, Andri Steinþór; Sigurðsson, Engilbert; Aspelund, Thor; Valdimarsdóttir, Unnur Anna (2024-01)
    BACKGROUND: Adverse childhood experiences (ACEs) are well-known risk factors for schizophrenia and bipolar disorder. AIMS: The aim was to study the associations between specific ACEs and psychological functioning in women with schizophrenia or bipolar ...
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    Adverse childhood experiences and resilience among adult women : A population-based study 
    Daníelsdóttir, Hilda Björk; Aspelund, Thor; Thordardottir, Edda Bjork; Fall, Katja; Fang, Fang; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Yang, Qian; Choi, Karmel W; Kennedy, Beatrice; Halldorsdottir, Thorhildur; Lu, Donghao; Song, Huan; Jakobsdóttir, Jóhanna; Hauksdóttir, Arna; Valdimarsdóttir, Unnur Anna (2022-02-01)
    Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional ...
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    Adverse childhood experiences, mental distress, and autoimmune disease in adult women : Findings from two large cohort studies 
    Köhler-Forsberg, Ole; Ge, Fenfen; Aspelund, Thor; Wang, Yue; Fang, Fang; Tomasson, Gunnar; Thordadottir, Edda; Hauksdóttir, Arna; Song, Huan; Valdimarsdottir, Unnur A. (2025-02-11)
    Background Adverse childhood experiences (ACEs) have been associated with increased risks of autoimmune diseases. However, data are scarce on the role of specific ACEs as well as the potential mediating role of adverse mental health symptoms in this ...
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    Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018 
    Thórsson, Bolli; Guðmundsson, Elías Freyr; Sigurðsson, Gunnar; Aspelund, Thor; Guðnason, Vilmundur G. (2021-05)
    INNGANGUR Fjöldi fólks með sykursýki 2 hefur vaxið undanfarna áratugi á Íslandi. Í þessari rannsókn var notaður Lyfjagagnagrunnur Embættis landlæknis til að meta algengi og nýgengi sykursýki 2 og sett fram spá um algengi sykursýki 2 eftir 10 og 20 ár. ...
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    Antihypertensive medication uses and serum ACE2 levels 
    Emilsson, Valur; Gudmundsson, Elias F.; Aspelund, Thor; Jonsson, Brynjolfur G.; Gudjonsson, Alexander; Launer, Lenore J.; Jennings, Lori L.; Gudmundsdottir, Valborg; Gudnason, Vilmundur (2020-05-25)
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    Association between Adverse Childhood Experiences and Multiple Sclerosis in Icelandic Women-A Population-Based Cohort Study 
    Gatto, Nicole M; Þórðardóttir, Edda Björk; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Song, Huan; Jakobsdóttir, Jóhanna; Aspelund, Thor; Valdimarsdóttir, Unnur Anna; Hauksdóttir, Arna (2022-11-16)
    BACKGROUND: A growing literature, mostly based on selected populations, indicates that traumas may be associated with autoimmune diseases, yet few studies exist on adverse childhood experiences (ACEs) and multiple sclerosis (MS) in the general population. ...
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    Association between adverse childhood experiences and premenstrual disorders : a cross-sectional analysis of 11,973 women 
    Yang, Qian; Þórðardóttir, Edda Björk; Hauksdóttir, Arna; Aspelund, Thor; Jakobsdóttir, Jóhanna; Halldorsdottir, Thorhildur; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Daníelsdóttir, Hilda Björk; Bertone-Johnson, Elizabeth R; Sjölander, Arvid; Fang, Fang; Lu, Donghao; Valdimarsdóttir, Unnur Anna (2022-02-21)
    Background: Childhood abuse and neglect have been associated with premenstrual disorders (PMDs), including premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). However, the associations of other adverse childhood experiences (ACEs) ...
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    Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilun 
    Hólmgeirsdóttir, Kristín Elísabet; Jonsson, Brynjolfur Gauti; Aspelund, Thor; Gudmundsson, Gunnar; Gudlaugsson, Janus (2019-11)
    TILGANGUR Takmarkaðar upplýsingar er að finna um árangur hjartaendurhæfingar fyrir hjartabilaða einstaklinga á Íslandi. Markmið þessarar rannsóknar var að greina hvort hjartaendurhæfing (stig ll) á HL-stöðinni í Reykjavík skilaði aukinni líkamlegri ...
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    Áhrif menntunar á áhættuþætti og nýgengi æðakölkunarsjúkdóma 
    Andersen, Karl Konráð; Aspelund, Thor; Gudmundsson, Elias Freyr; Sigurdsson, Gunnar; Sigurdsson, Sigurdur; Björnsdóttir, Guðlaug; Thorsson, Bolli; Sigurdsson, Gunnar; Hardarsson, Thordur; Gudnason, Vilmundur (2022-07-07)
    INNGANGUR Lágt menntunarstig hefur verið tengt óhagstæðri samsetningu áhættuþátta kransæðasjúkdóma. Þessu fylgir aukin áhætta á hjartaáföllum hjá minna menntuðum. Litlar upplýsingar eru til um samband menntunarstigs við alvarleika æðakölkunarsjúkdóma. ...
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    Coding and regulatory variants affect serum protein levels and common disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur; Gudjonsson, Alexander; Karim, Mohd A; Jonsson, Brynjolfur G (2020-05-08)
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    Coding and regulatory variants are associated with serum protein levels and disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Gudjonsson, Alexander; Jonmundsson, Thorarinn; Jonsson, Brynjolfur G; Karim, Mohd A; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur (2022-01-25)
    Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current study, 54,469 low-frequency and common ...
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    Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants 
    Aspelund, Thor; Gudnason, Vilmundur (Oxford University Press (OUP), 2018-03-19)
    Background Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure ...
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    Correlates of Coronavirus Disease 2019 Inpatient Mortality at a Southern California Community Hospital With a Predominantly Hispanic/Latino Adult Population 
    Gatto, Nicole M; Freund, Debbie; Ogata, Pamela; Diaz, Lisa; Ibarrola, Ace; Desai, Mamta; Aspelund, Thor; Gluckstein, Daniel (2023-01-10)
    BACKGROUND: Studies of inpatient coronavirus disease 2019 (COVID-19) mortality risk factors have mainly used data from academic medical centers or large multihospital databases and have not examined populations with large proportions of Hispanic/Latino ...
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    COVID-19 illness severity and 2-year prevalence of physical symptoms : an observational study in Iceland, Sweden, Norway and Denmark 
    Shen, Qing; Joyce, Emily E.; Ebrahimi, Omid V.; Didriksen, Maria; Lovik, Anikó; Sævarsdóttir, Karen Sól; Magnúsdóttir, Ingibjörg; Mikkelsen, Dorte Helenius; Unnarsdóttir, Anna Bára; Hauksdóttir, Arna; Hoffart, Asle; Kähler, Anna K.; Þórðardóttir, Edda Björk; Eythórsson, Elías; Frans, Emma M.; Tómasson, Gunnar; Ask, Helga; Harðardóttir, Hrönn; Jakobsdóttir, Jóhanna; Lehto, Kelli; Lu, Li; Andreassen, Ole A.; Sullivan, Patrick F.; Pálsson, Runólfur; Erikstrup, Christian; Ostrowski, Sisse Rye; Werge, Thomas; Aspelund, Thor; Pedersen, Ole B.V.; Johnson, Sverre Urnes; Fang, Fang; Valdimarsdóttir, Unnur Anna (2023-12-01)
    Background: Although the persistence of physical symptoms after SARS-CoV-2 infection is a major public health concern, evidence from large observational studies beyond one year post diagnosis remain scarce. We aimed to assess the prevalence of physical ...
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    Depressive symptom trajectories among general population during the COVID-19 pandemic in Iceland: a prospective cohort study (2020–2023) 
    Wang, Yue; Hauksdóttir, Arna; Thordardottir, Edda Bjork; Ge, Fenfen; Gísladóttir, Elísabet Unnur; Jakobsdóttir, Jóhanna; Ásbjörnsdóttir, Kristjana Hrönn; Rúnarsdóttir, Harpa; Unnarsdóttir, Anna Bára; Magnúsdóttir, Ingibjörg; Love, Thorvardur Jon; Kristinsson, Sigurdur Yngvi; Palsson, Runolfur; Zoega, Helga; Fang, Fang; Tómasson, Gunnar; Song, Huan; Aspelund, Thor; Valdimarsdottir, Unnur (2024-11)
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    Determining hemodilution in diagnostic bone marrow aspirated samples in plasma cell disorders by next-generation flow cytometry : Proposal for a bone marrow quality index 
    Óskarsson, Jón Þórir; Rögnvaldsson, Sæmundur; Thorsteinsdottir, Sigrun; Aspelund, Thor; Gunnarsson, Steinar Bragi; Hákonardóttir, Guðlaug Katrín; Sigurðardóttir, Guðrún Ásta; Þórðardóttir, Ásdís Rósa; Gíslason, Gauti Kjartan; Ólafsson, Andri; Sigurðsson, Jón Kristinn; Eyþórsson, Elías; Jónsson, Ásbjörn; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni A.; Pálmason, Róbert; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Harding, Stephen; Flores-Montero, Juan; Orfao, Alberto; Durie, Brian G.M.; Love, Thorvardur Jon; Kristinsson, Sigurdur Yngvi (2023-12-01)
    Hemodilution of bone marrow (BM) aspirates is a limitation of multiparameter flow cytometry (MFC) in plasma cell disorders. There is a need for a validated approach for assessing sample quality and the distribution of non-plasma cell BM populations by ...
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    Dietary habits in adolescence and midlife and risk of breast cancer in older women 
    Haraldsdottir, Alfheidur; Torfadottir, Johanna; Valdimarsdottir, Unnur; Adami, Hans-Olov; Aspelund, Thor; Tryggvadottir, Laufey; Þórðardóttir, Maríanna; Birgisdottir, Bryndis Eva; Harris, Tamara B.; Launer, Lenore J.; Gudnason, Vilmundur; Steingrimsdottir, Laufey (Public Library of Science (PLoS), 2018-05-30)
    Recent studies indicate that lifestyle factors in early life affect breast cancer risk. We therefore explored the association of high consumption of meat, milk, and whole grain products in adolescence and midlife, on breast cancer risk. We used data ...
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    Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts 
    Aspelund, Thor; Grübler, Martin R.; Smith, Albert Vernon; Gudmundsson, Elias Freyr; Keppel, Martin; Cotch, Mary Frances; Harris, Tamara B.; Jorde, Rolf; Grimnes, Guri; Joakimsen, Ragnar; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; März, Winfried; Kleber, Marcus E.; Tomaschitz, Andreas; Grove-Laugesen, Diana; Rejnmark, Lars; Swart, Karin M. A.; Brouwer, Ingeborg A.; Lips, Paul; Van Schoor, Natasja M.; Sempos, Christopher T.; Durazo-Arvizu, Ramón A.; Škrabáková, Zuzana; Dowling, Kirsten G.; Cashman, Kevin D.; Kiely, Mairead; Pilz, Stefan; Gudnason, Vilmundur; Eiriksdottir, Gudny (MDPI AG, 2019-01-02)
    The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship by using a Mendelian randomisation (MR) approach with genetic variants in the vitamin D ...