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Browsing by Author "Aspelund, Thor"

Browsing by Author "Aspelund, Thor"

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    1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function 
    Gorski, Mathias; van der Most, Peter J.; Teumer, Alexander; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Nolte, Ilja M.; Cocca, Massimiliano; Taliun, Daniel; Gomez, Felicia; Li, Yong; Tayo, Bamidele; Tin, Adrienne; Feitosa, Mary F.; Aspelund, Thor; Attia, John; Biffar, Reiner; Bochud, Murielle; Boerwinkle, Eric; Borecki, Ingrid; Bottinger, Erwin P.; Chen, Ming-Huei; Chouraki, Vincent; Ciullo, Marina; Coresh, Josef; Cornelis, Marilyn C.; Curhan, Gary C.; d’Adamo, Adamo Pio; Dehghan, Abbas; Dengler, Laura; Ding, Jingzhong; Eiríksdóttir, Guðný; Endlich, Karlhans; Enroth, Stefan; Esko, Tõnu; Franco, Oscar H.; Gasparini, Paolo; Gieger, Christian; Girotto, Giorgia; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Hancock, Stephen J.; Harris, Tamara B.; Helmer, Catherine; Höllerer, Simon; Hofer, Edith; Hofman, Albert; Holliday, Elizabeth G.; Homuth, Georg; Hu, Frank B.; Huth, Cornelia; Hutri-Kähönen, Nina; Hwang, Shih-Jen; Imboden, Medea; Johansson, Åsa; Kähönen, Mika; König, Wolfgang; Kramer, Holly; Krämer, Bernhard K.; Kumar, Ashish; Kutalik, Zoltán; Lambert, Jean-Charles; Launer, Lenore J.; Lehtimäki, Terho; de Borst, Martin; Navis, Gerjan; Swertz, Morris; Liu, Yongmei; Lohman, Kurt; Loos, Ruth J. F.; Lu, Yingchang; Lyytikäinen, Leo-Pekka; McEvoy, Mark A.; Meisinger, Christa; Meitinger, Thomas; Metspalu, Andres; Metzger, Marie; Mihailov, Evelin; Mitchell, Paul; Nauck, Matthias; Oldehinkel, Albertine J.; Olden, Matthias; WJH Penninx, Brenda; Pistis, Giorgio; Pramstaller, Peter P.; Probst-Hensch, Nicole; Raitakari, Olli T.; Rettig, Rainer; Ridker, Paul M.; Rivadeneira, Fernando; Robino, Antonietta; Rosas, Sylvia E.; Ruderfer, Douglas; Ruggiero, Daniela; Saba, Yasaman; Sala, Cinzia; Schmidt, Helena; Schmidt, Reinhold; Scott, Rodney J.; Sedaghat, Sanaz; Smith, Albert Vernon; Sorice, Rossella; Stengel, Benedicte; Stracke, Sylvia; Strauch, Konstantin; Toniolo, Daniela; Uitterlinden, André G.; Ulivi, Sheila; Viikari, Jorma S.; Völker, Uwe; Vollenweider, Peter; Völzke, Henry; Vuckovic, Dragana; Waldenberger, Melanie; Jin Wang, Jie; Yang, Qiong; Chasman, Daniel I.; Tromp, Gerard; Snieder, Harold; Heid, Iris M.; Fox, Caroline S.; Köttgen, Anna; Pattaro, Cristian; Böger, Carsten A.; Fuchsberger, Christian (Springer Nature, 2017-04-28)
    HapMap imputed genome-wide association studies (GWAS) have revealed >50 loci at which common variants with minor allele frequency >5% are associated with kidney function. GWAS using more complete reference sets for imputation, such as those from The ...
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    ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19 
    Emilsson, Valur; Gudmundsson, Elias F; Aspelund, Thor; Jonsson, Brynjolfur G; Gudjonsson, Alexander; Launer, Lenore J.; Lamb, John R; Gudmundsdottir, Valborg; Jennings, Lori L; Gudnason, Vilmundur (2020-06-05)
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    Adverse childhood experiences and resilience among adult women : A population-based study 
    Daníelsdóttir, Hilda Björk; Aspelund, Thor; Thordardottir, Edda Bjork; Fall, Katja; Fang, Fang; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Yang, Qian; Choi, Karmel W; Kennedy, Beatrice; Halldorsdottir, Thorhildur; Lu, Donghao; Song, Huan; Jakobsdóttir, Jóhanna; Hauksdóttir, Arna; Valdimarsdóttir, Unnur Anna (2022-02-01)
    Background: Adverse childhood experiences (ACEs) have consistently been associated with elevated risk of multiple adverse health outcomes, yet their contribution to coping ability and psychiatric resilience in adulthood is unclear. Methods: Cross-sectional ...
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    Algengi og nýgengi sykursýki 2 á Íslandi frá 2005 til 2018 
    Thórsson, Bolli; Guðmundsson, Elías Freyr; Sigurðsson, Gunnar; Aspelund, Thor; Guðnason, Vilmundur G. (2021-05)
    INNGANGUR Fjöldi fólks með sykursýki 2 hefur vaxið undanfarna áratugi á Íslandi. Í þessari rannsókn var notaður Lyfjagagnagrunnur Embættis landlæknis til að meta algengi og nýgengi sykursýki 2 og sett fram spá um algengi sykursýki 2 eftir 10 og 20 ár. ...
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    Antihypertensive medication uses and serum ACE2 levels 
    Emilsson, Valur; Gudmundsson, Elias F.; Aspelund, Thor; Jonsson, Brynjolfur G.; Gudjonsson, Alexander; Launer, Lenore J.; Jennings, Lori L.; Gudmundsdottir, Valborg; Gudnason, Vilmundur (2020-05-25)
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    Association between Adverse Childhood Experiences and Multiple Sclerosis in Icelandic Women-A Population-Based Cohort Study 
    Gatto, Nicole M; Þórðardóttir, Edda Björk; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Song, Huan; Jakobsdóttir, Jóhanna; Aspelund, Thor; Valdimarsdóttir, Unnur Anna; Hauksdóttir, Arna (2022-11-16)
    BACKGROUND: A growing literature, mostly based on selected populations, indicates that traumas may be associated with autoimmune diseases, yet few studies exist on adverse childhood experiences (ACEs) and multiple sclerosis (MS) in the general population. ...
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    Association between adverse childhood experiences and premenstrual disorders : a cross-sectional analysis of 11,973 women 
    Yang, Qian; Þórðardóttir, Edda Björk; Hauksdóttir, Arna; Aspelund, Thor; Jakobsdóttir, Jóhanna; Halldorsdottir, Thorhildur; Tómasson, Gunnar; Rúnarsdóttir, Harpa; Daníelsdóttir, Hilda Björk; Bertone-Johnson, Elizabeth R; Sjölander, Arvid; Fang, Fang; Lu, Donghao; Valdimarsdóttir, Unnur Anna (2022-02-21)
    Background: Childhood abuse and neglect have been associated with premenstrual disorders (PMDs), including premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). However, the associations of other adverse childhood experiences (ACEs) ...
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    Áhrif hjartaendurhæfingar á líkamlega afkastagetu einstaklinga með hjartabilun 
    Hólmgeirsdóttir, Kristín Elísabet; Jonsson, Brynjolfur Gauti; Aspelund, Thor; Gudmundsson, Gunnar; Gudlaugsson, Janus (2019-11)
    TILGANGUR Takmarkaðar upplýsingar er að finna um árangur hjartaendurhæfingar fyrir hjartabilaða einstaklinga á Íslandi. Markmið þessarar rannsóknar var að greina hvort hjartaendurhæfing (stig ll) á HL-stöðinni í Reykjavík skilaði aukinni líkamlegri ...
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    Áhrif menntunar á áhættuþætti og nýgengi æðakölkunarsjúkdóma 
    Andersen, Karl Konráð; Aspelund, Thor; Gudmundsson, Elias Freyr; Sigurdsson, Gunnar; Sigurdsson, Sigurdur; Björnsdóttir, Guðlaug; Thorsson, Bolli; Sigurdsson, Gunnar; Hardarsson, Thordur; Gudnason, Vilmundur (2022-07-07)
    INNGANGUR Lágt menntunarstig hefur verið tengt óhagstæðri samsetningu áhættuþátta kransæðasjúkdóma. Þessu fylgir aukin áhætta á hjartaáföllum hjá minna menntuðum. Litlar upplýsingar eru til um samband menntunarstigs við alvarleika æðakölkunarsjúkdóma. ...
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    Coding and regulatory variants affect serum protein levels and common disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur; Gudjonsson, Alexander; Karim, Mohd A; Jonsson, Brynjolfur G (2020-05-08)
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    Coding and regulatory variants are associated with serum protein levels and disease 
    Emilsson, Valur; Gudmundsdottir, Valborg; Gudjonsson, Alexander; Jonmundsson, Thorarinn; Jonsson, Brynjolfur G; Karim, Mohd A; Ilkov, Marjan; Staley, James R; Gudmundsson, Elias F; Launer, Lenore J; Lindeman, Jan H; Morton, Nicholas M; Aspelund, Thor; Lamb, John R; Jennings, Lori L; Gudnason, Vilmundur (2022-01-25)
    Circulating proteins can be used to diagnose and predict disease-related outcomes. A deep serum proteome survey recently revealed close associations between serum protein networks and common disease. In the current study, 54,469 low-frequency and common ...
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    Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants 
    Aspelund, Thor; Gudnason, Vilmundur (Oxford University Press (OUP), 2018-03-19)
    Background Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure ...
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    Dietary habits in adolescence and midlife and risk of breast cancer in older women 
    Haraldsdottir, Alfheidur; Torfadottir, Johanna; Valdimarsdottir, Unnur; Adami, Hans-Olov; Aspelund, Thor; Tryggvadottir, Laufey; Þórðardóttir, Maríanna; Birgisdottir, Bryndis Eva; Harris, Tamara B.; Launer, Lenore J.; Gudnason, Vilmundur; Steingrimsdottir, Laufey (Public Library of Science (PLoS), 2018-05-30)
    Recent studies indicate that lifestyle factors in early life affect breast cancer risk. We therefore explored the association of high consumption of meat, milk, and whole grain products in adolescence and midlife, on breast cancer risk. We used data ...
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    Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts 
    Aspelund, Thor; Grübler, Martin R.; Smith, Albert Vernon; Gudmundsson, Elias Freyr; Keppel, Martin; Cotch, Mary Frances; Harris, Tamara B.; Jorde, Rolf; Grimnes, Guri; Joakimsen, Ragnar; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Njølstad, Inger; Løchen, Maja-Lisa; März, Winfried; Kleber, Marcus E.; Tomaschitz, Andreas; Grove-Laugesen, Diana; Rejnmark, Lars; Swart, Karin M. A.; Brouwer, Ingeborg A.; Lips, Paul; Van Schoor, Natasja M.; Sempos, Christopher T.; Durazo-Arvizu, Ramón A.; Škrabáková, Zuzana; Dowling, Kirsten G.; Cashman, Kevin D.; Kiely, Mairead; Pilz, Stefan; Gudnason, Vilmundur; Eiriksdottir, Gudny (MDPI AG, 2019-01-02)
    The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship by using a Mendelian randomisation (MR) approach with genetic variants in the vitamin D ...
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    Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies 
    Pennells, Lisa; Kaptoge, Stephen; Wood, Angela; Sweeting, Mike; Zhao, Xiaohui; White, Ian; Burgess, Stephen; Willeit, Peter; Bolton, Thomas; Moons, Karel G M; van der Schouw, Yvonne T; Selmer, Randi; Khaw, Kay-Tee; Gudnason, Vilmundur; Assmann, Gerd; Amouyel, Philippe; Salomaa, Veikko; Kivimaki, Mika; Nordestgaard, Børge G; Blaha, Michael J; Kuller, Lewis H; Brenner, Hermann; Gillum, Richard F; Meisinger, Christa; Ford, Ian; Knuiman, Matthew W; Rosengren, Annika; Lawlor, Debbie A; Völzke, Henry; Cooper, Cyrus; Marín Ibañez, Alejandro; Casiglia, Edoardo; Kauhanen, Jussi; Cooper, Jackie A; Rodriguez, Beatriz; Sundström, Johan; Barrett-Connor, Elizabeth; Dankner, Rachel; Nietert, Paul J; Davidson, Karina W; Wallace, Robert B; Blazer, Dan G; Björkelund, Cecilia; Donfrancesco, Chiara; Krumholz, Harlan M; Nissinen, Aulikki; Davis, Barry R; Coady, Sean; Whincup, Peter H; Jørgensen, Torben; Ducimetiere, Pierre; Trevisan, Maurizio; Engström, Gunnar; Crespo, Carlos J; Meade, Tom W; Visser, Marjolein; Kromhout, Daan; Kiechl, Stefan; Daimon, Makoto; Price, Jackie F; Gómez de la Cámara, Agustin; Wouter Jukema, J; Lamarche, Benoît; Onat, Altan; Simons, Leon A; Kavousi, Maryam; Ben-Shlomo, Yoav; Gallacher, John; Dekker, Jacqueline M; Arima, Hisatomi; Shara, Nawar; Tipping, Robert W; Roussel, Ronan; Brunner, Eric J; Koenig, Wolfgang; Sakurai, Masaru; Pavlovic, Jelena; Gansevoort, Ron T; Nagel, Dorothea; Goldbourt, Uri; Barr, Elizabeth L M; Palmieri, Luigi; Njølstad, Inger; Sato, Shinichi; Monique Verschuren, W M; Varghese, Cherian V; Graham, Ian; Onuma, Oyere; Greenland, Philip; Woodward, Mark; Ezzati, Majid; Psaty, Bruce M; Sattar, Naveed; Jackson, Rod; Ridker, Paul M; Cook, Nancy R; D'Agostino, Ralph B; Thompson, Simon G; Danesh, John; Di Angelantonio, Emanuele; Tipping, Robert W; Simpson, Lara M; Pressel, Sara L; Couper, David J; Nambi, Vijay; Matsushita, Kunihiro; Folsom, Aaron R; Shaw, Jonathan E; Magliano, Dianna J; Zimmet, Paul Z; Knuiman, Matthew W; Whincup, Peter H; Wannamethee, S Goya; Willeit, Johann; Santer, Peter; Egger, Georg; Casas, Juan Pablo; Amuzu, Antointtte; Ben-Shlomo, Yoav; Gallacher, John; Tikhonoff, Valérie; Casiglia, Edoardo; Sutherland, Susan E; Nietert, Paul J; Cushman, Mary; Psaty, Bruce M; Søgaard, Anne Johanne; Håheim, Lise Lund; Ariansen, Inger; Tybjærg-Hansen, Anne; Jensen, Gorm B; Schnohr, Peter; Giampaoli, Simona; Vanuzzo, Diego; Panico, Salvatore; Palmieri, Luigi; Balkau, Beverley; Bonnet, Fabrice; Marre, Michel; de la Cámara, Agustin Gómez; Rubio Herrera, Miguel Angel; Friedlander, Yechiel; McCallum, John; McLachlan, Stela; Guralnik, Jack; Phillips, Caroline L; Guralnik, Jack; Guralnik, Jack; Guralnik, Jack; Khaw, Kay-Tee; Wareham, Nick; Schöttker, Ben; Saum, Kai-Uwe; Holleczek, Bernd; Nissinen, Aulikki; Tolonen, Hanna; Giampaoli, Simona; Donfrancesco, Chiara; Vartiainen, Erkki; Jousilahti, Pekka; Harald, Kennet; D’Agostino, Ralph B; Massaro, Joseph M; Pencina, Michael; Vasan, Ramachandran; D’Agostino, Ralph B; Massaro, Joseph M; Pencina, Michael; Vasan, Ramachandran; Kayama, Takamasa; Kato, Takeo; Oizumi, Toshihide; Jespersen, Jørgen; Møller, Lars; Bladbjerg, Else Marie; Chetrit, A; Rosengren, Annika; Wilhelmsen, Lars; Björkelund, Cecilia; Lissner, Lauren; Nagel, Dorothea; Dennison, Elaine; Kiyohara, Yutaka; Ninomiya, Toshiharu; Doi, Yasufumi; Rodriguez, Beatriz; Nijpels, Giel; Stehouwer, Coen D A; Sato, Shinichi; Kazumasa, Yamagishi; Iso, Hiroyasu; Goldbourt, Uri; Salomaa, Veikko; Vartiainen, Erkki; Kurl, Sudhir; Tuomainen, Tomi-Pekka; Salonen, Jukka T; Visser, Marjolein; Deeg, Dorly J H; Meade, Tom W; Nilsson, Peter M; Hedblad, Bo; Melander, Olle; De Boer, Ian H; DeFilippis, Andrew Paul; Verschuren, W M Monique; Sattar, Naveed; Watt, Graham; Meisinger, Christa; Koenig, Wolfgang; Koenig, Wolfgang; Meisinger, Christa; Verschuren, W M Monique; Rosengren, Annika; Kuller, Lewis H; Tverdal, Aage; Gillum, Richard F; Cooper, Jackie A; Kirkland, Susan; Shimbo, Daichi; Shaffer, Jonathan; Sato, Shinichi; Kazumasa, Yamagishi; Iso, Hiroyasu; Ducimetiere, Pierre; Bakker, Stephan J L; van der Harst, Pim; Hillege, Hans L; Crespo, Carlos J; Amouyel, Philippe; Dallongeville, Jean; Assmann, Gerd; Schulte, Helmut; Trompet, Stella; Smit, Roelof A J; Stott, David J; van der Schouw, Yvonne T; Després, Jean-Pierre; Cantin, Bernard; Dagenais, Gilles R; Laughlin, Gail; Wingard, Deborah; Khaw, Kay-Tee; Trevisan, Maurizio; Aspelund, Thor; Eiriksdottir, Gudny; Guðmundsson, Elías Freyr; Ikram, Arfan; van Rooij, Frank J A; Franco, Oscar H; Rueda-Ochoa, Oscar L; Muka, Taulant; Glisic, Marija; Tunstall-Pedoe, Hugh; Völzke, Henry; Howard, Barbara V; Zhang, Ying; Jolly, Stacey; Gallacher, John; Davey-Smith, George; Can, Günay; Yüksel, Hüsniye; Nakagawa, Hideaki; Morikawa, Yuko; Miura, Katsuyuki; Njølstad, Inger; Ingelsson, Martin; Giedraitis, Vilmantas; Ridker, Paul M; Gaziano, J Michael; Kivimaki, Mika; Shipley, Martin; Brunner, Eric J; Shipley, Martin; Arndt, Volker; Brenner, Hermann; Cook, Nancy; Ridker, Paul M; Ford, Ian; Sattar, Naveed; Ibañez, Alejandro Marín; Geleijnse, Johanna M (Oxford University Press (OUP), 2018-11-22)
    Aims: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that ...
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    Fractures and survival in multiple myeloma : results from a population-based study 
    Thorsteinsdottir, Sigrun; Gislason, Gauti; Aspelund, Thor; Sverrisdottir, Ingigerdur; Landgren, Ola; Turesson, Ingemar; Björkholm, Magnus; Kristinsson, Sigurður Yngvi (2020-04-01)
    Multiple myeloma causes lytic bone lesions and fractures. The impact of fractures on multiple myeloma (MM) survival is unclear. The aim of this study was to evaluate the effect of fractures on survival in MM using data from MM patients diagnosed in ...
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    Greiningarferli lungnakrabbameins á Landspítala: sjúklingamiðuð nálgun 
    Harðardóttir, Hrönn; Valdimarsdottir, Unnur; Gudbjartsson, Tomas; Sigvaldason, Andrés; Lund, Sigrún Helga; Aspelund, Thor; Hansdottir, Sif; Jónsson, Steinn (Læknafélag Íslands / Icelandic Medical Association, 2017-04-06)
    Inngangur: Markmið rannsóknarinnar var að lýsa einkennum, sjúkdómsmynd, meðferð og afdrifum sjúklinga sem hafa farið í kerfisbundið greiningarferli á Landspítala vegna gruns um lungnakrabbamein. Efniviður og aðferðir: Rannsóknin tekur til 550 sjúklinga ...
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    Gæði fitu í mataræðinu hefur áhrif á heilsu okkar 
    Torfadóttir, Jóhanna E.; Þorgeirsdóttir, Hólmfríður; Aspelund, Thor (2021)
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    Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories : a pooled analysis of 2181 population-based studies with 65 million participants 
    Rodriguez-Martinez, Andrea; Zhou, Bin; Sophiea, Marisa K.; Bentham, James; Paciorek, Christopher J.; Iurilli, Maria LC; Carrillo-Larco, Rodrigo M.; Bennett, James E.; Di Cesare, Mariachiara; Taddei, Cristina; Bixby, Honor; Stevens, Gretchen A.; Riley, Leanne M.; Cowan, Melanie J.; Savin, Stefan; Danaei, Goodarz; Chirita-Emandi, Adela; Kengne, Andre P.; Khang, Young Ho; Laxmaiah, Avula; Malekzadeh, Reza; Miranda, J. Jaime; Moon, Jin Soo; Popovic, Stevo R.; Sørensen, Thorkild IA; Soric, Maroje; Starc, Gregor; Zainuddin, Ahmad A.; Gregg, Edward W.; Bhutta, Zulfiqar A.; Black, Robert; Abarca-Gómez, Leandra; Abdeen, Ziad A.; Abdrakhmanova, Shynar; Abdul Ghaffar, Suhaila; Abdul Rahim, Hanan F.; Abu-Rmeileh, Niveen M.; Abubakar Garba, Jamila; Acosta-Cazares, Benjamin; Adams, Robert J.; Aekplakorn, Wichai; Afsana, Kaosar; Afzal, Shoaib; Agdeppa, Imelda A.; Aghazadeh-Attari, Javad; Aguilar-Salinas, Carlos A.; Aspelund, Thor; Gudnason, Vilmundur; Koziel, Slawomir; Olafsson, Örn (2020-11-07)
    Background: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what ...
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    Hyperuricemia is associated with intermittent hand joint pain in a cross sectional study of elderly females: The AGES-Reykjavik Study 
    Jonsson, Helgi; Aspelund, Thor; Eiriksdottir, Gudny; Harris, Tamara B.; Launer, Lenore J.; Gudnason, Vilmundur (Public Library of Science (PLoS), 2019-08-23)
    Background: The debate whether "asymptomatic hyperuricemia" should be treated is still ongoing. The objective of this cross-sectional study was to analyze whether hyperuricema in the elderly is associated with joint pain. Methods and findings: Participants ...