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Fletta eftir efnisorði "Immunology"

Fletta eftir efnisorði "Immunology"

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    Erratum : Correction: Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction (Cell death & disease (2016) 7 (e2238)) 
    Hall, A. R.; Burke, N.; Dongworth, R. K.; Kalkhoran, Siavash Beikoghli; Dyson, A.; Vicencio, J. M.; Dorn, G. W.; Yellon, D. M.; Hausenloy, D. J. (2021-06-30)
    The original version of this article unfortunately contained a mistake in an author name. The correct author name is GW Dorn 2nd. The original article has been corrected.
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    EULAR recommendations for the management of ANCA-associated vasculitis : 2022 update 
    Hellmich, Bernhard; Sanchez-Alamo, Beatriz; Schirmer, Jan H.; Berti, Alvise; Blockmans, Daniel; Cid, Maria C.; Holle, Julia U.; Hollinger, Nicole; Karadag, Omer; Kronbichler, Andreas; Little, Mark A.; Luqmani, Raashid A.; Mahr, Alfred; Merkel, Peter A.; Mohammad, Aladdin J.; Monti, Sara; Mukhtyar, Chetan B.; Musial, Jacek; Price-Kuehne, Fiona; Segelmark, Mårten; Teng, Y. K.Onno; Terrier, Benjamin; Tómasson, Gunnar; Vaglio, Augusto; Vassilopoulos, Dimitrios; Verhoeven, Peter; Jayne, David (2023-03-16)
    Background: Since the publication of the EULAR recommendations for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several randomised clinical trials have been published that have the potential to change ...
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    A European-Japanese study on peach allergy : IgE to Pru p 7 associates with severity 
    Kallen, E J J; Revers, A; Fernández-Rivas, M; Asero, R; Ballmer-Weber, B; Barreales, L; Belohlavkova, S; de Blay, F; Clausen, Michael Valur; Dubakiene, R; Ebisawa, M; Fernández-Perez, C; Fritsche, P; Fukutomi, Y; Gislason, David; Hoffmann-Sommergruber, K; Jedrzejczak-Czechowicz, M; Knulst, A C; Kowalski, M L; Kralimarkova, T; Lidholm, J; Metzler, C; Mills, E N C; Papadopoulos, N G; Popov, T A; Purohit, A; Reig, I; Seneviratne, S L; Sinaniotis, A; Takei, M; Versteeg, S A; Vassilopoulou, A E; Vieths, S; Welsing, P M J; Zwinderman, A H; Le, T M; Van Ree, R (2023-09)
    BACKGROUND: Pru p 3 and Pru p 7 have been implicated as risk factors for severe peach allergy. This study aimed to establish sensitization patterns to five peach components across Europe and in Japan, to explore their relation to pollen and foods and ...
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    Expired human platelets for mesenchymal stromal cell propagation 
    Jonsdottir-Buch, Sandra Mjoll (University of Iceland, School of Health Sciences, Faculty of Medicine, 2017-09-15)
    Mesenchymal stromal cells (MSC) are promising candidates for cellular therapy due to their ability to regenerate bone and cartilage and modulate immune responses. The use of MSC in cellular therapy is problematic due to the need for fetal bovine serum ...
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    Exposure to specific tumour necrosis factor inhibitors and risk of demyelinating and inflammatory neuropathy in cohorts of patients with inflammatory arthritis : a collaborative observational study across five Nordic rheumatology registers 
    Delcoigne, Benedicte; Kopp, Tine Iskov; Arkema, Elizabeth V.; Hellgren, Karin; Provan, Sella Aarrestad; Relas, Heikki; Aaltonen, Kalle; Trokovic, Nina; Guðbjörnsson, Björn; Gröndal, Gerður María; Klami Kristianslund, Eirik; Lindhardsen, Jesper; Dreyer, Lene; Askling, Johan (2023-02-28)
    Objective To compare incidences of neuroinflammatory events, including demyelinating disease (DML), inflammatory polyneuropathies (IPN) and multiple sclerosis (MS), in patients with rheumatoid arthritis (RA) or spondyloarthritis (SpA; including psoriatic ...
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    Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis 
    Aradottir, Sigridur Sunna; Kristoffersson, Ann Charlotte; Roumenina, Lubka T.; Bjerre, Anna; Kashioulis, Pavlos; Pálsson, Runólfur; Karpman, Diana (2021-06-10)
    Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
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    Hematopoietic Stem Cell Transplantation Resolves the Immune Deficit Associated with STAT3-Dominant-Negative Hyper-IgE Syndrome 
    Harrison, Stephanie C.; Tsilifis, Christo; Slatter, Mary A.; Nademi, Zohreh; Worth, Austen; Veys, Paul; Ponsford, Mark J.; Jolles, Stephen; Al-Herz, Waleed; Flood, Terence; Cant, Andrew J.; Doffinger, Rainer; Barcenas-Morales, Gabriela; Carpenter, Ben; Hough, Rachael; Haraldsson, Ásgeir; Heimall, Jennifer; Grimbacher, Bodo; Abinun, Mario; Gennery, Andrew R. (2021-02-01)
    Autosomal dominant hyper-IgE syndrome caused by dominant-negative loss-of-function mutations in signal transducer and activator of transcription factor 3 (STAT3) (STAT3-HIES) is a rare primary immunodeficiency with multisystem pathology. The quality ...
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    HER-3 surface expression increases in advanced colorectal cancer representing a potential therapeutic target 
    Capone, Emily; Tryggvason, Þórður; Cela, Ilaria; Dufrusine, Beatrice; Pinti, Morena; Del Pizzo, Francesco; Gunnarsdóttir, Helga Sigrún; Grottola, Tommaso; De Laurenzi, Vincenzo; Iacobelli, Stefano; Lattanzio, Rossano; Sala, Gianluca (2023-10-28)
    HER-3 (also known as ErbB-3) is a human epidermal growth factor receptor tyrosine kinases family member, and its expression in CRC (colorectal cancer) tissues was previously associated with poor prognosis. In this study, HER-3 expression was analyzed ...
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    Is tea consumption associated with reduction of risk of rheumatoid arthritis? A Swedish case-control study 
    Westerlind, Helga; Palmqvist, Ida; Saevarsdottir, Saedis; Alfredsson, Lars; Klareskog, Lars; Di Giuseppe, Daniela (2021-08-07)
    BACKGROUND: Tea is a popular beverage around the world and has properties that can affect the immune system. The association between tea consumption and the risk of rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, ...
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    Long-Term Follow-Up of Newborns with 22q11 Deletion Syndrome and Low TRECs 
    Framme, Jenny Lingman; Lundqvist, Christina; Lundell, Anna Carin; van Schouwenburg, Pauline A.; Lemarquis, Andri L.; Thörn, Karolina; Lindgren, Susanne; Gudmundsdottir, Judith; Lundberg, Vanja; Degerman, Sofie; Zetterström, Rolf H.; Borte, Stephan; Hammarström, Lennart; Telemo, Esbjörn; Hultdin, Magnus; van der Burg, Mirjam; Fasth, Anders; Oskarsdóttir, Sólveig; Ekwall, Olov (2022-01-26)
    Background: Population-based neonatal screening using T-cell receptor excision circles (TRECs) identifies infants with profound T lymphopenia, as seen in cases of severe combined immunodeficiency, and in a subgroup of infants with 22q11 deletion syndrome ...
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    LT-K63 Enhances B Cell Activation and Survival Factors in Neonatal Mice That Translates Into Long-Lived Humoral Immunity 
    Aradottir Pind, Audur Anna; Molina Estupiñan, Jenny Lorena; Magnusdottir, Gudbjorg Julia; Del Giudice, Giuseppe; Jonsdottir, Ingileif; Bjarnarson, Stefania P. (2020-10-23)
    Adjuvants enhance magnitude and duration of immune responses induced by vaccines. In this study we assessed in neonatal mice if and how the adjuvant LT-K63 given with a pneumococcal conjugate vaccine, Pnc1-TT, could affect the expression of tumor ...
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    Management of Nail Disease in Patients With Psoriatic Arthritis : An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations 
    Laheru, Dhruvkumar; Antony, Anna; Carneiro, Sueli; Di Lernia, Vito; Garg, Amit; Löve, Þorvarður Jón; Del Rocio Macias Garcia, Karla; Mendonça, José Alexandre; Mukherjee, Sandeep; Olteanu, Rodica; Perez-Chada, Lourdes; Rosen, Cheryl F; Tannenbaum, Rachel; Yazbek, Michel Alexandre (2023-03-01)
    OBJECTIVE: Nail psoriasis is common, impairs fine motor finger functioning, affects cosmesis, and is associated with a lower quality of life. This review updates the previous Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) ...
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    Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect 
    Styrkársdóttir, Unnur; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Andri Stefánsson, Ólafur; Sævarsdóttir, Sædís; Lund, Sigrún Helga; Rafnar, Thorunn; Hoshijima, Kazuyuki; Novak, Kendra; Oreiro, Natividad; Rego-Perez, Ignacio; Hansen, Channing; Kazmers, Nikolas; Kiemeney, Lambertus A; Blanco, Francisco J; Barker, Tyler; Kloppenburg, Margreet; Jurynec, Michael J; Gudbjartsson, Daniel F; Jónsson, Helgi; Þorsteinsdóttir, Unnur; Stefánsson, Kári (2023-06)
    OBJECTIVES: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been associated with hand OA but none with EHOA. ...
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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, Lilja; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, Helgi; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, Helga; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, Þorsteinn; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study 
    Hedenstierna, Louise; Hedström, Anna Karin; Klareskog, Lars; Di Giuseppe, Daniela; Alfredsson, Lars; Askling, Johan; Ernestam, Sofia; Saevarsdottir, Saedis; Ljung, Lotta (2022-08-23)
    Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: ...
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    Normal neonatal TREC and KREC levels in early onset juvenile idiopathic arthritis 
    Guðmundsdóttir, Judith Amalía; Thorgeirsdottir, Sigridur; Lundbäck, Veroniqa; Göngrich, Christina; Lingman Framme, Jenny; Kindgren, Erik; Rydenman, Karin; Lúðvíksson, Björn Rúnar; Bjarnadóttir, Helga; Runarsdottir, Saga; Nilsson, Staffan; Zetterström, Rolf H.; Ekwall, Olov; Lindgren, Susanne (2023-04)
    Objective: Dysregulated central tolerance predisposes to autoimmune diseases. Reduced thymic output as well as compromised central B cell tolerance checkpoints have been proposed in the pathogenesis of juvenile idiopathic arthritis (JIA). The aim of ...
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    Pentraxins CRP-I and CRP-II are post-translationally deiminated and differ in tissue specificity in cod (Gadus morhua L.) ontogeny 
    Magnadottir, Bergljot; Hayes, Polly; Gísladóttir, Berglind; Bragason, Birkir; Hristova, Mariya; Nicholas, Anthony P.; Guðmundsdóttir, Sigríður; Lange, Sigrun (Elsevier BV, 2018-10)
    Pentraxins arefluid phase pattern recognition molecules that form an important part of the innate immunedefence and are conserved betweenfish and human. In Atlantic cod (Gadus morhuaL.), two pentraxin-likeproteins have been described, CRP-I and CRP-II. ...
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    Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial 
    Stockfelt, Marit; Lundell, Anna Carin; Hetland, Merete Lund; Østergaard, Mikkel; Uhlig, Till; Heiberg, Marte Schrumpf; Haavardsholm, Espen A.; Nurmohamed, Michael T.; Lampa, Jon; Nordström, Dan; Petersen, Kim Hørslev; Guðbjörnsson, Björn; Gröndal, Gerður; Aldridge, Jonathan; Andersson, Kerstin; Blennow, Kaj; Zetterberg, Henrik; van Vollenhoven, Ronald; Rudin, Anna (2021-07-13)
    Background: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics ...
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    Risk Factors for Diagnosis of Psoriatic Arthritis, Psoriasis, Rheumatoid Arthritis, and Ankylosing Spondylitis : A Set of Parallel Case-control Studies 
    Meer, Elana; Thrastardottir, Telma; Wang, Xingmei; Dubreuil, Maureen; Chen, Yong; Gelfand, Joel M.; Love, Thorvardur J.; Ogdie, Alexis (2022-01-01)
    Objective. To compare potential risk factors for the diagnosis of psoriatic arthritis (PsA), psoriasis (PsO), rheumatoid arthritis (RA), and ankylosing spondylitis (AS). Methods. Four parallel case-control studies were conducted within The Health ...
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    Sex differences in the effectiveness of first-line tumour necrosis factor inhibitors in axial spondyloarthritis : Results from the EuroSpA Research Collaboration Network 
    Hellamand, Pasoon; Van De Sande, Marleen; Ørnbjerg, Lykke Midtbøll; Klausch, Thomas; Nurmohamed, Michael T.; Van Vollenhoven, Ronald F.; Nordström, Dan; Hokkanen, Anna Mari; Santos, Maria Jose; Vieira-Sousa, Elsa; Loft, Anne G.; Glintborg, Bente; Hetland, Merete Lund; Lindström, Ulf; Wallman, Johan K.; Michelsen, Brigitte; Klami Kristianslund, Eirik; Ciurea, Adrian; Nissen, Michael S.; Codreanu, Catalin; Mogosan, Corina; Macfarlane, Gary J.; Rotariu, Ovidiu; Rotar, Ziga; Tomšič, Matija; Castrejon, Isabel; Otero-Varela, Lucia; Guðbjörnsson, Björn; Geirsson, Árni Jón; Vencovský, Ji; Pavelka, Karel; Gulle, Semih; Zengin, Berrin; Iannone, Florenzo; Foti, Rosario; Ostergaard, Mikkel; Van Der Horst-Bruinsma, Irene (2023-12-12)
    Objective Evidence indicates reduced treatment effectiveness of TNFi in women with axial spondyloarthritis (axSpA) compared with men. We aimed to investigate sex differences in treatment response and retention rates over 24 months of follow-up in axSpA ...