Opin vísindi

Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study

Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study


Title: Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study
Author: Hedenstierna, Louise
Hedström, Anna Karin
Klareskog, Lars
Di Giuseppe, Daniela
Alfredsson, Lars
Askling, Johan
Ernestam, Sofia
Saevarsdottir, Saedis   orcid.org/0000-0001-9392-6184
Ljung, Lotta
Date: 2022-08-23
Language: English
Scope: 203
Department: Faculty of Medicine
Internal Medicine and Emergency Services
Series: Arthritis Research and Therapy; 24(1)
ISSN: 1478-6354
DOI: https://doi.org/10.1186/s13075-022-02892-w
Subject: Antirheumatic Agents/therapeutic use; Arthritis, Rheumatoid/drug therapy; C-Reactive Protein; Cohort Studies; Humans; Remission Induction; Severity of Illness Index; Social Support; Sweden/epidemiology; Rheumatology; Immunology and Allergy; Immunology
URI: https://hdl.handle.net/20.500.11815/3892

Show full item record

Citation:

Hedenstierna , L , Hedström , A K , Klareskog , L , Di Giuseppe , D , Alfredsson , L , Askling , J , Ernestam , S , Saevarsdottir , S & Ljung , L 2022 , ' Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study ' , Arthritis Research and Therapy , vol. 24 , no. 1 , 203 , pp. 203 . https://doi.org/10.1186/s13075-022-02892-w

Abstract:

Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: This cohort study included all patients enrolled in both the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) 1996–2015 and the Swedish Rheumatology Quality Register (SRQ, n = 2820). Information on social support and decision latitude at work at RA diagnosis were identified from the EIRA questionnaire. Indexes for levels of social support and decision latitude at work, respectively, were calculated based on the questionnaire. Low social support and low decision latitude at work, respectively, were identified by a score in the lowest quartile and compared with the three other quartiles (not low). Disease-activity parameters were retrieved from SRQ at 3, 12, and 60 months. The associations between social support or decision latitude at work, respectively, and Disease Activity Score 28 joint count with C-reactive protein (DAS28-CRP) remission were analysed using logistic regression models adjusted for age, sex, smoking habits, alcohol habits, symptom duration, and educational level. Results: Having low social support (n = 591) was not associated with DAS28-CRP remission at 3 (OR 0.93, 95% CI 0.74–1.16), 12 (OR 0.96, 95%CI 0.75–1.23), or 60 (OR 0.89, 95%CI 0.72–1.10) months compared to not low social support (n = 2209). No association was observed for low (n = 212) versus not low (n = 635) decision latitude at work and DAS28-CRP remission at 3 (OR 0.84, 95%CI 0.54–1.31), 12 (OR 0.81, 95%CI 0.56–1.16), or 60 (OR 1.37, 95%CI 0.94–2.01) months. Conclusion: In a country with general access to healthcare, psychosocial vulnerability does not influence the likelihood of achieving remission in early RA.

Description:

Funding Information: Open access funding provided by Karolinska Institute. The EIRA study and the authors have been supported by grants from the Swedish Research Council, the Region Stockholm (ALF), the Swedish Heart Lung Foundation, the Swedish Council for Health, Working Life and Welfare, King Gustaf V’s 80-Year Foundation, and the Swedish Rheumatism Foundation. LH was supported by research funding from Börje Dahlin’s research fund. Publisher Copyright: © 2022, The Author(s).

Files in this item

This item appears in the following Collection(s)