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Browsing by Author "Freysdóttir, Jóna"

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Dietary Fish Oil Increases the Number of CD11b+CD27− NK Cells at the Inflammatory Site and Enhances Key Hallmarks of Resolution of Murine Antigen-Induced Peritonitis

Jensen, Kirstine Nolling; Heijink, Marieke; Giera, Martin; Freysdóttir, Jóna; Harðardóttir, Ingibjörg (2022-01-01)

Purpose: To determine the effects of dietary omega-3 polyunsaturated fatty acids (PUFAs) on recruitment of natural killer (NK) cells and resolution responses in antigen-induced peritonitis in mice. Methods: Mice were fed fish oil-enriched or control ...
Emu Oil and Saireito in combination reduce tumour development and clinical indicators of disease in a mouse model of colitis-associated colorectal cancer

Chartier, Lauren C.; Fujino, Junko; Howarth, Gordon S.; Freysdóttir, Jóna; Harðardóttir, Ingibjörg; Mashtoub, Suzanne (2021-06)

BACKGROUND: Emu Oil (EO) previously demonstrated therapeutic potential in a mouse model of colitis-associated CRC (CA-CRC). Saireito, a traditional Japanese medicine, has not been investigated in CA-CRC. AIM: To determine whether EO and Saireito could ...
Geobarrettin D, a Rare Herbipoline-Containing 6-Bromoindole Alkaloid from Geodia barretti

Di, Xiaxia; Harðardóttir, Ingibjörg; Freysdóttir, Jóna; Wang, Dongdong; Gustafson, Kirk R; Ómarsdóttir, Sesselja Sigurborg; Molinski, Tadeusz F (2023-04)

Geobarrettin D (1), a new bromoindole alkaloid, was isolated from the marine sponge Geodia barretti collected from Icelandic waters. Its structure was elucidated by 1D, and 2D NMR (including 1H-15N HSQC, 1H-15N HMBC spectra), as well as HRESIMS data. ...

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