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Detecting arousals and sleep from respiratory inductance plethysmography
(2025-05) Finnsson, Eysteinn; Erlingsson, Ernir; Hlynsson, Hlynur D.; Valsdóttir, Vaka; Sigmarsdottir, Thora B.; Arnardóttir, Eydís; Sands, Scott A.; Jónsson, Sigurður; Islind, Anna S.; Ágústsson, Jón S.; Department of Computer Science; Department of Psychology
Purpose: Accurately identifying sleep states (REM, NREM, and Wake) and brief awakenings (arousals) is essential for diagnosing sleep disorders. Polysomnography (PSG) is the gold standard for such assessments but is costly and requires overnight monitoring in a lab. Home sleep testing (HST) offers a more accessible alternative, relying primarily on breathing measurements but lacks electroencephalography, limiting its ability to evaluate sleep and arousals directly. This study evaluates a deep learning algorithm which determines sleep states and arousals from breathing signals. Methods: A novel deep learning algorithm was developed to classify sleep states and detect arousals from respiratory inductance plethysmography signals. Sleep states were predicted for 30-s intervals (one sleep epoch), while arousal probabilities were calculated at 1-s resolution. Validation was conducted on a clinical dataset of 1,299 adults with suspected sleep disorders. Performance was assessed at the epoch level for sensitivity and specificity, with agreement analyses for arousal index (ArI) and total sleep time (TST). Results: The algorithm achieved sensitivity and specificity of 77.9% and 96.2% for Wake, 93.9% and 80.4% for NREM, 80.5% and 98.2% for REM, and 66.1% and 86.7% for arousals. Bland–Altman analysis showed ArI limits of agreement ranging from - 32 to 24 events/hour (bias: - 4.4) and TST limits from - 47 to 64 min (bias: 8.0). Intraclass correlation was 0.74 for ArI and 0.91 for TST. Conclusion: The algorithm identifies sleep states and arousals from breathing signals with agreement comparable to established variability in manual scoring. These results highlight its potential to advance HST capabilities, enabling more accessible, cost-effective and reliable sleep diagnostics.
Verk
Design principles for enhancing a digital health platform for patients with atrial fibrillation
(2025-10-01) Jóhannsdóttir, Lilja Guðrún; Erlingsdóttir, Helga Ýr; Gizurarson, Sigfús Örvar; Guðmundsson, Kristján; Kristjánsdóttir, Herdís; Jónsson, Björn; Óskarsdóttir, María; Islind, Anna Sigríður; Department of Computer Science
Objective: Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice and is associated with an elevated risk of stroke, heart failure, dementia, and mortality. As its clinical consequences are strongly influenced by modifiable risk factors, this study aims to design a patient journey for individuals undergoing AF treatment, with the goal of improving patient safety and healthcare delivery. Methods: An empirical study was conducted using an action design research approach. The research focused on identifying and implementing design principles to enhance digital health platforms and support AF management. Results: The study resulted in five key design principles: (i) comprehensive requests for medical interventions, (ii) visualization of patient trajectories, (iii) prioritization of waiting lists informed by real-time data, (iv) equality and inclusion throughout the patient journey, and (v) rapid access to and visualization of quality indicators. These principles collectively address current challenges in AF care by optimizing data use, strengthening patient involvement, and improving decision-making. Conclusion: We propose adjustments to the design of digital health platforms for AF management based on the identified principles. Such adaptations have the potential to enhance patient safety, improve healthcare delivery, and create more efficient, inclusive, and data-driven processes in AF management.
Verk
Why it is important to conduct gambling research that is fair and free from conflicts of interest
(2025-04) Roberts, Amanda; Rogers, Jim; Sharman, Steve; Stark, Sasha; Dymond, Simon; Ludvig, Elliot A.; Tunney, Richard J.; O’Reilly, Matthew; Young, Matthew M.; Department of Psychology
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Correction to : Biological and psychological predictors of cognitive function in breast cancer patients before surgery (Supportive Care in Cancer, (2024), 32, 1, (88), 10.1007/s00520-023-08282-5)
(2025-05) Aspelund, Snaefridur Gudmundsdottir; Halldorsdottir, Thorhildur; Agustsson, Gudjon; Tobin, Hannah Ros Sigurdardottir; Wu, Lisa M.; Amidi, Ali; Johannsdottir, Kamilla R.; Lutgendorf, Susan K.; Telles, Rachel; Daly, Huldis Franksdottir; Sigurdardottir, Kristin; Valdimarsdottir, Heiddis B.; Baldursdottir, Birna; Department of Psychology
Correction to: Supportive Care in Cancer (2024) 32:88. https://doi.org/10.1007/s00520-023-08282-5. During the writing of a PhD thesis, an error was identified in the published article “Biological and psychological predictors of cognitive function in breast cancer patients before surgery”. Due to an R coding error, participants with stage 0 breast cancer were initially removed but were inadvertently reintroduced during later data merging. Consequently, these cases were not excluded from the final analyses as intended. Demographic and clinical characteristics of breast cancer patients compared with the healthy control group (Corrected) Women with breast cancer (N = 112) Healthy controls (N = 67) Age in years (mean, SD) 61.8 (10.7) 60.9 (9.5) 0.57 Currently partnered, N(%) 1 Yes 74 (66.1%) 44 (65.7%) No 33 (29.5%) 19 (28.4%) Education level, N(%) 0.55 Primary 18 (16.1%) 10 (14.9%) Secondary 36 (32.1%) 17 (25.4%) University 53 (47.3%) 37 (55.2%) BMI (mean, SD) 27.7 (5.0) 28.1 (4.8) 0.61 Physical activity, N(%) 0.48 None 17 (15.2%) 12 (17.9%) Once a week 10 (8.9%) 2 (3.0%) Twice a week 16 (14.3%) 10 (14.9%) ≥ 3 times a week 64 (57.1%) 40 (59.7%) Menopause, yes % 88 (78.6%) 56 (83.6%) 0.62 Cortisol (mean, SD) 5.1 (2.1) - - α-amylase (mean, SD) 140.5 (94.8) - - Depressive symptoms (mean, SD) 11.0 (8.5) 8.8 (7.3) 0.08 Anxiety symptoms (mean, SD) 4.1 (3.8) 2.8 (3.3) 0.02* Overall cancer-related stress (mean, SD) 25.5 (14.6) - - Average time since diagnosis (weeks) 3.2 - - Cancer stage, N(%) 0 4 (3.6%) - - I 57 (50.9%) - - II 41 (36.6%) - - III 10 (8.9%) - - HER- 2 positive, N(%) 8 (7.1%) - - Estrogen positive, N(%) 101 (90.2%) - - Progesterone positive, N(%) 80 (71.4%) - - BMI = Body Mass Index; HER- 2 = human epidermal growth factor receptor 2 * = p < 0.05 (two-sided). Two-sample t-tests were performed for continuous variables to compare means between groups, and chi-squared tests were used for categorical variables to test for group differences The original article has been corrected.

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