General trans-diagnostic late effects of cancer and cancer treatment

Abstract

Many of the growing population of cancer survivors experience general biopsychosocial late effects, including depression, fear of recurrence, insomnia, fatigue, cognitive difficulties, and chronic pain, with a substantial impact on quality of life and functioning. This review finds evidence for psychological, behavioural, physical, and selected pharmacological interventions. Recently developed Danish clinical practice guidelines provide evidence-based recommendations for assessment and treatment, highlighting the need for coordinated, cross-sectoral implementation to ensure equitable, high-quality survivorship care.