dc.contributor.author |
Guðnadóttir, Sandra Dögg |
dc.contributor.author |
Gunnarsdóttir, Ingibjörg |
dc.contributor.author |
Hernandez, Ubaldo Benitez |
dc.contributor.author |
Ingadóttir, Áróra Rós |
dc.date.accessioned |
2024-04-10T01:06:26Z |
dc.date.available |
2024-04-10T01:06:26Z |
dc.date.issued |
2024-06 |
dc.identifier.citation |
Guðnadóttir , S D , Gunnarsdóttir , I , Hernandez , U B & Ingadóttir , Á R 2024 , ' High risk of malnutrition among hospitalised coronavirus disease 2019 (COVID-19) patients is associated with mortality and other clinical outcomes ' , Clinical Nutrition ESPEN , vol. 61 , pp. 1-7 . https://doi.org/10.1016/j.clnesp.2024.02.023 |
dc.identifier.issn |
2405-4577 |
dc.identifier.other |
219413907 |
dc.identifier.other |
facffed7-fce9-459a-8ddc-fad5a69522e3 |
dc.identifier.other |
85187322933 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/4793 |
dc.description |
Publisher Copyright: © 2024 The Author(s) |
dc.description.abstract |
Introduction: Increasing evidence indicates an association between nutritional status and Coronavirus disease 2019 (COVID-19) disease severity. The aim of the study was to describe the risk of malnutrition, body mass index (BMI) and vitamin D status of hospitalised COVID-19 patients and assess whether they are associated with duration of hospital stay, intensive care unit (ICU) admission, mechanical ventilation, and mortality. Methods: The study is a descriptive retrospective study of 273 patients with COVID-19 admitted to Hospital from February 2020 to March 2021. Patients were screened for risk of malnutrition using a validated screening tool. BMI was calculated from height and weight. Insufficient Vitamin D status was defined as 25(OH)vitD <50 nmol/L. Logistic regression analysis was used to assess the association between indicators of nutritional status of patients with COVID-19, and outcomes such as duration of stay >7 days, ICU admission, mechanical ventilation, and mortality. Interaction between risk of malnutrition and BMI of ≥30 kg/m2 was assessed using the likelihood ratio test with hospital stay, ICU admission, mechanical ventilation, and mortality as outcomes. Results: Screening for risk of malnutrition identified 201 (74%) patients at a medium to high risk of malnutrition. Patients defined as being at a medium or high risk of malnutrition were more likely to be hospitalised for >7 days compared to those defined as low risk (OR: 10.72; 95% CI: 3.9–29.46; p < 0.001 and OR: 61.57; 95% CI: 19.48–194.62; p < 0.001, respectively). All patients who were admitted to ICU (n = 41) and required mechanical ventilation (n = 27) were defined as having medium or high risk of malnutrition. High risk of malnutrition was also associated with increased odds of mortality (OR: 8.87; 955 CI 1.08–72,96; p = 0.042). BMI of ≥30 kg/m2 (43%) and 25(OH)vitD <50 nmol/L (20%) were not associated with duration of stay >7 days or mortality, although BMI ≥30 kg/m2 was associated with increased risk of ICU admission (OR: 7.12; 95% CI: 1.59–31.94; p = 0.010) and mechanical ventilation (OR: 8.86; 95% CI: 1.12–69.87; p = 0.038). Interactions between risk of malnutrition and BMI ≥30 kg/m2 were not significant to explain the outcomes of hospital stay >7 days, ICU admission, mechanical ventilation, or mortality. Conclusion: High risk of malnutrition among hospitalised COVID-19 patients was associated with longer duration of hospital stay, ICU admission, mechanical ventilation and mortality, and BMI ≥30 kg/m2 was associated with ICU admission and mechanical ventilation. Insufficient Vitamin D status was not associated with duration of hospital stay, ICU admission, mechanical ventilation, or mortality. |
dc.format.extent |
7 |
dc.format.extent |
342511 |
dc.format.extent |
1-7 |
dc.language.iso |
en |
dc.relation.ispartofseries |
Clinical Nutrition ESPEN; 61() |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Næringarfræðingar |
dc.subject |
Náttúrufræðingar |
dc.subject |
BMI |
dc.subject |
ICU admission |
dc.subject |
Nutrition status |
dc.subject |
Vitamin D |
dc.subject |
Endocrinology, Diabetes and Metabolism |
dc.subject |
Nutrition and Dietetics |
dc.title |
High risk of malnutrition among hospitalised coronavirus disease 2019 (COVID-19) patients is associated with mortality and other clinical outcomes |
dc.type |
/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version |
Peer reviewed |
dc.identifier.doi |
10.1016/j.clnesp.2024.02.023 |
dc.relation.url |
http://www.scopus.com/inward/record.url?scp=85187322933&partnerID=8YFLogxK |
dc.contributor.department |
Other departments |
dc.contributor.department |
Faculty of Food Science and Nutrition |
dc.contributor.school |
Health Sciences |