dc.contributor |
Landspítali |
dc.contributor.author |
Sturluson, Olafur Orri |
dc.contributor.author |
Pálsson, Ólafur |
dc.contributor.author |
Hjaltested, Einar Kristinn |
dc.contributor.author |
Lúðvíksdóttir, Dóra |
dc.date.accessioned |
2024-02-17T01:04:15Z |
dc.date.available |
2024-02-17T01:04:15Z |
dc.date.issued |
2024-01-01 |
dc.identifier.citation |
Sturluson , O O , Pálsson , Ó , Hjaltested , E K & Lúðvíksdóttir , D 2024 , ' Smáæðabólga með rauðkyrningafjöld, EGPA, falinn fylgisjúkdómur astma? • Sjúkratilfelli • ' , Læknablaðið , bind. 110 , nr. 1 , bls. 28-32 . https://doi.org/10.17992/lbl.2024.01.777 |
dc.identifier.issn |
0023-7213 |
dc.identifier.other |
215161567 |
dc.identifier.other |
4ddd0439-1b5e-45b5-a164-30ae982ba6a3 |
dc.identifier.other |
85180734003 |
dc.identifier.other |
38126794 |
dc.identifier.other |
unpaywall: 10.17992/lbl.2024.01.777 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/4720 |
dc.description |
Publisher Copyright: © 2024 Laeknafelag Islands. All rights reserved. |
dc.description.abstract |
A 72-year-old woman presented to the emergency department due to worsening dyspnea. She had been diagnosed with asthma a year earlier. At arrival, her oxygen saturation was only 84%. During lung auscultation, wheezing was noted over all lung fields. A blood test showed a significant increase in eosinophils in peripheral blood, highest value of 1.4 x 10E9/L. Further investigations in the respiratory ward showed a positive MPO-ANCA, which, together with clinical features of asthma, chronic rhinosinusitis with polyps, mononeuritis multiplex and eosinophilia, led to the diagnosis of eosinophilic granulomatosis with polyangiitis, or what used to be called Churg-Strauss syndrome. Corticosteroid treatment was initiated and subsequently tapered down when treatment with mepolizumab was started, which is an IL-5 inhibitor. Her symptoms quickly became much better. Frequent exacerbations and pulmonary symptoms became things of the past. |
dc.format.extent |
5 |
dc.format.extent |
3298398 |
dc.format.extent |
28-32 |
dc.language.iso |
is |
dc.relation.ispartofseries |
Læknablaðið; 110(1) |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Gigtarlæknisfræði |
dc.subject |
Háls- nef og eyrnaskurðlæknisfræði |
dc.subject |
Lungnalæknisfræði |
dc.subject |
EGPA |
dc.subject |
asthma |
dc.subject |
eosinophilic granulomatosis with polyangiitis |
dc.subject |
mepolizumab |
dc.subject |
Lung/diagnostic imaging |
dc.subject |
Churg-Strauss Syndrome/complications |
dc.subject |
Humans |
dc.subject |
Female |
dc.subject |
Aged |
dc.subject |
Asthma/drug therapy |
dc.subject |
Granulomatosis with Polyangiitis/complications |
dc.subject |
Almenn læknisfræði |
dc.title |
Smáæðabólga með rauðkyrningafjöld, EGPA, falinn fylgisjúkdómur astma? • Sjúkratilfelli • |
dc.title.alternative |
Eosinophilic small vessel vasculites (EGPA) a hidden severe asthma comorbitity |
dc.type |
/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version |
Peer reviewed |
dc.identifier.doi |
10.17992/lbl.2024.01.777 |
dc.relation.url |
http://www.scopus.com/inward/record.url?scp=85180734003&partnerID=8YFLogxK |
dc.contributor.department |
Læknadeild |