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Residential greenspace and lung function decline over 20 years in a prospective cohort : The ECRHS study

Residential greenspace and lung function decline over 20 years in a prospective cohort : The ECRHS study

Title: Residential greenspace and lung function decline over 20 years in a prospective cohort : The ECRHS study
Author: Markevych, Iana
Zhao, Tianyu
Fuertes, Elaine
Marcon, Alessandro
Dadvand, Payam
Vienneau, Danielle
Garcia Aymerich, Judith
Nowak, Dennis
de Hoogh, Kees
Jarvis, Deborah
... 36 more authors Show all authors
Date: 2023-08
Language: English
Scope: 108036
Department: Faculty of Medicine
Internal Medicine and Emergency Services
Series: Environment international; 178()
ISSN: 0160-4120
DOI: https://doi.org/10.1016/j.envint.2023.108036
Subject: Lungnalæknisfræði; ECRHS; FEV; FVC; Green space; Nature; Spirometry; Prospective Studies; Humans; Lung; Middle Aged; Air Pollution/analysis; Forced Expiratory Volume; Vital Capacity; Adult; Female; Environmental Science (all)
URI: https://hdl.handle.net/20.500.11815/4354

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Markevych , I , Zhao , T , Fuertes , E , Marcon , A , Dadvand , P , Vienneau , D , Garcia Aymerich , J , Nowak , D , de Hoogh , K , Jarvis , D , Abramson , M J , Accordini , S , Amaral , A F , Bentouhami , H , Jacobsen Bertelsen , R , Boudier , A , Bono , R , Bowatte , G , Casas , L , Dharmage , S C , Forsberg , B , Gíslason , Þ , Gnesi , M , Holm , M , Jacquemin , B , Janson , C , Jogi , R , Johannessen , A , Keidel , D , Leynaert , B , Maldonado Perez , J A , Marchetti , P , Migliore , E , Martínez-Moratalla , J , Orru , H , Pin , I , Potts , J , Probst-Hensch , N , Ranzi , A , Sánchez-Ramos , J L , Siroux , V , Soussan , D , Sunyer , J , Urrutia Landa , I , Villani , S & Heinrich , J 2023 , ' Residential greenspace and lung function decline over 20 years in a prospective cohort : The ECRHS study ' , Environment international , vol. 178 , 108036 , pp. 108036 . https://doi.org/10.1016/j.envint.2023.108036


BACKGROUND: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is affected. OBJECTIVE: We explored the association between residential greenspace and change in lung function over 20 years in 5559 adults from 22 centers in 11 countries participating in the population-based, international European Community Respiratory Health Survey. METHODS: Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were measured by spirometry when participants were approximately 35 (1990-1994), 44 (1999-2003), and 55 (2010-2014) years old. Greenness was assessed as the mean Normalized Difference Vegetation Index (NDVI) in 500 m, 300 m, and 100 m circular buffers around the residential addresses at the time of lung function measurement. Green spaces were defined as the presence of agricultural, natural, or urban green spaces in a circular 300 m buffer. Associations of these greenspace parameters with the rate of lung function change were assessed using adjusted linear mixed effects regression models with random intercepts for subjects nested within centers. Sensitivity analyses considered air pollution exposures. RESULTS: A 0.2-increase (average interquartile range) in NDVI in the 500 m buffer was consistently associated with a faster decline in FVC (-1.25 mL/year [95% confidence interval: -2.18 to -0.33]). These associations were especially pronounced in females and those living in areas with low PM10 levels. We found no consistent associations with FEV1 and the FEV1/FVC ratio. Residing near forests or urban green spaces was associated with a faster decline in FEV1, while agricultural land and forests were related to a greater decline in FVC. CONCLUSIONS: More residential greenspace was not associated with better lung function in middle-aged European adults. Instead, we observed slight but consistent declines in lung function parameters. The potentially detrimental association requires verification in future studies.


Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. Funding Information: We thank all participants for their cooperation, as well as all technical, administrative support staffs, and medical and field work teams. We are also grateful to all members of the European Community Respiratory Health Survey. Funding Information: Elaine Fuertes is support by the Imperial College Research Fellowship. Funding Information: The authors appreciate the support provided by the National Natural Science Foundation of China (M-0420). Funding Information: Iana Markevych is supported from the “NeuroSmog: Determining the impact of air pollution on the developing brain” (Nr. POIR.04.04.00–1763/18–00) which is implemented as part of the TEAM-NET programme of the Foundation for Polish Science, co-financed from EU resources, obtained from the European Regional Development Fund under the Smart Growth Operational Programme. Funding Information: The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study ( https://www.alecstudy.org ), which has also received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health are reported in the Supplementary Material . ISGlobal is a member of CERCA Programme/Generalitat de Catalunya. These sources of funding had no role in the study design, the collection, analysis and interpretation of data, the writing of the report, and in the decision to submit the article for publication. Funding Information: This study was specifically funded by the German Research Foundation (GZ: KA 4737/2–1 | NO 262/13–1 | HE 3294/12–1) and the Comprehensive Pneumology Center Munich (CPC-M), German Center for Lung Research (DZL), Munich, Germany. Funding Information: We acknowledge support from the Spanish Ministry of Science and Innovation through the “Centro de Excelencia Severo Ochoa 2019–2023” Program (CEX2018-000806-S), and support from the Generalitat de Catalunya through the CERCA Program to ISGlobal. Publisher Copyright: © 2023 The Authors

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