Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea

Pak, Victoria M; Maislin, David G; Keenan, Brendan T.; Guo, Xiaofeng; Townsend, Ray; Benediktsdóttir, Bryndís; Pack, Allan I.; Gíslason, Þórarinn; Kuna, Samuel T.

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Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea

Titill:	Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea
Höfundur:	Pak, Victoria M Maislin, David G Keenan, Brendan T. Guo, Xiaofeng Townsend, Ray Benediktsdóttir, Bryndís Pack, Allan I. Gíslason, Þórarinn Kuna, Samuel T. 9 höfundar Sýna færri höfunda
Útgáfa:	2023-03
Tungumál:	Enska
Umfang:	327013
Háskóli/Stofnun:	Landspitali - The National University Hospital of Iceland
Svið:	Health Sciences
Deild:	Faculty of Medicine Internal Medicine and Emergency Services
Birtist í:	ERJ Open Research; 9(2)
ISSN:	2312-0541
DOI:	10.1183/23120541.00443-2022
Efnisorð:	Lungnalæknisfræði; Pulmonary and Respiratory Medicine; SDG 3 - Good Health and Well-being
URI:	https://hdl.handle.net/20.500.11815/4159
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Tilvitnun: Pak, V M, Maislin, D G, Keenan, B T, Guo, X, Townsend, R, Benediktsdóttir, B, Pack, A I, Gíslason, Þ & Kuna, S T 2023, 'Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea', ERJ Open Research, vol. 9, no. 2, 00443-2022. https://doi.org/10.1183/23120541.00443-2022
Útdráttur: This study found no evidence that obesity significantly modifies the effect of 4 months of CPAP treatment on HOMA-IR. Longer duration of CPAP treatment may be needed in order to reduce insulin resistance and determine whether obesity modifies the effect. https://bit.ly/3CtX7jZ.
Athugasemdir: Funding Information: Support statement: This study was supported by grant P01-HL094307 from the National Heart, Lung, and Blood Institute (principal investigator: A.I. Pack). Funding information for this article has been deposited with the Crossref Funder Registry.