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Health-related quality of life as associated with asthma control, psychological status and insomnia

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dc.contributor.author Rask-Andersen, Anna
dc.contributor.author Leander, Mai
dc.contributor.author Sundbom, Fredrik
dc.contributor.author Lampa, Erik
dc.contributor.author Oudin, Anna
dc.contributor.author Leynaert, Bénédicte
dc.contributor.author Svanes, Cecilie
dc.contributor.author Gíslason, Þórarinn
dc.contributor.author Torén, Kjell
dc.contributor.author Janson, Christer
dc.date.accessioned 2023-03-17T01:03:31Z
dc.date.available 2023-03-17T01:03:31Z
dc.date.issued 2022
dc.identifier.citation Rask-Andersen , A , Leander , M , Sundbom , F , Lampa , E , Oudin , A , Leynaert , B , Svanes , C , Gíslason , Þ , Torén , K & Janson , C 2022 , ' Health-related quality of life as associated with asthma control, psychological status and insomnia ' , Upsala Journal of Medical Sciences , vol. 127 . https://doi.org/10.48101/ujms.v127.8967
dc.identifier.issn 0300-9734
dc.identifier.other PURE: 104717214
dc.identifier.other PURE UUID: f61e9a33-b810-484b-8c39-b55eb614d14a
dc.identifier.other PubMedCentral: PMC9793762
dc.identifier.other Scopus: 85145345024
dc.identifier.uri https://hdl.handle.net/20.500.11815/4076
dc.description © 2022 The Author(s). Published by Upsala Medical Society.
dc.description.abstract BACKGROUND: Asthma is associated not only with lower health-related quality of life (HRQL) but also with psychological health and insomnia. The aim of this study was to investigate associations between HRQL, asthma symptoms, psychological status and insomnia in adults from three Nordic countries. METHODS: This study comprised 2,270 subjects aged 29-55 from Sweden, Iceland and Norway. HRQL was measured with the 36-Item Short Form Health Survey (SF-36). The physical (PCS) and mental health (MCS) component scores were calculated with higher values, indicating better health status. Symptoms of depression and anxiety were measured using the Hospital Anxiety and Depression Scale (HADS). Insomnia was assessed with the Basic Nordic Sleep Questionnaire. An asthma score consisting of a sum of the positive answers to five respiratory symptoms was used in the analysis. Spirometry and allergy tests were also performed. RESULTS: High HADS and sleep disturbance scores were both related to a low PCS and MCS, respectively, after adjusting for confounders. High age and high body mass index (BMI) were associated with low scores on the PCS, whilst the opposite was found for the MCS. A higher asthma score was related to a low PCS. An interaction between the HADS and the asthma symptom score was observed for the PCS (P = 0.0002), where associations between psychological status and the PCS were more pronounced for individuals with more symptoms than for individuals without symptoms. CONCLUSIONS: In this study, we found that HRQL of life was independently related to the HADS, insomnia and asthma symptoms. Further prospective studies to identify the most efficient target for intervention in order to improve asthma control are needed.
dc.language.iso en
dc.relation.ispartofseries Upsala Journal of Medical Sciences; 127()
dc.rights info:eu-repo/semantics/restrictedAccess
dc.subject Lungnalæknisfræði
dc.subject Adult
dc.subject Humans
dc.subject Quality of Life
dc.subject Sleep Initiation and Maintenance Disorders
dc.subject Prospective Studies
dc.subject Asthma/complications
dc.subject Health Status
dc.subject Surveys and Questionnaires
dc.title Health-related quality of life as associated with asthma control, psychological status and insomnia
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.pmid 36590755
dc.identifier.doi https://doi.org/10.48101/ujms.v127.8967
dc.contributor.department Faculty of Medicine
dc.contributor.department Internal Medicine and Emergency Services

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