Opin vísindi

Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study

Show simple item record

dc.contributor.author BOLD Collaborative Research Group
dc.date.accessioned 2023-03-11T01:03:43Z
dc.date.available 2023-03-11T01:03:43Z
dc.date.issued 2023-01
dc.identifier.citation BOLD Collaborative Research Group 2023 , ' Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study ' , European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology , vol. 61 , no. 1 , 2200469 . https://doi.org/10.1183/13993003.00469-2022
dc.identifier.issn 0903-1936
dc.identifier.other PURE: 101753216
dc.identifier.other PURE UUID: 3154574a-df90-4bbc-9c1b-b27660c1dc3c
dc.identifier.other PubMedCentral: PMC9834632
dc.identifier.other Scopus: 85146364403
dc.identifier.other unpaywall: 10.1183/13993003.00469-2022
dc.identifier.uri https://hdl.handle.net/20.500.11815/4061
dc.description Copyright ©The authors 2023.
dc.description.abstract BACKGROUND: Chronic obstructive pulmonary disease has been associated with exposures in the workplace. We aimed to assess the association of respiratory symptoms and lung function with occupation in the Burden of Obstructive Lung Disease study. METHODS: We analysed cross-sectional data from 28 823 adults (≥40 years) in 34 countries. We considered 11 occupations and grouped them by likelihood of exposure to organic dusts, inorganic dusts and fumes. The association of chronic cough, chronic phlegm, wheeze, dyspnoea, forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1)/FVC with occupation was assessed, per study site, using multivariable regression. These estimates were then meta-analysed. Sensitivity analyses explored differences between sexes and gross national income. RESULTS: Overall, working in settings with potentially high exposure to dusts or fumes was associated with respiratory symptoms but not lung function differences. The most common occupation was farming. Compared to people not working in any of the 11 considered occupations, those who were farmers for ≥20 years were more likely to have chronic cough (OR 1.52, 95% CI 1.19-1.94), wheeze (OR 1.37, 95% CI 1.16-1.63) and dyspnoea (OR 1.83, 95% CI 1.53-2.20), but not lower FVC (β=0.02 L, 95% CI -0.02-0.06 L) or lower FEV1/FVC (β=0.04%, 95% CI -0.49-0.58%). Some findings differed by sex and gross national income. CONCLUSION: At a population level, the occupational exposures considered in this study do not appear to be major determinants of differences in lung function, although they are associated with more respiratory symptoms. Because not all work settings were included in this study, respiratory surveillance should still be encouraged among high-risk dusty and fume job workers, especially in low- and middle-income countries.
dc.format.extent
dc.language.iso en
dc.relation.ispartofseries European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology; 61(1)
dc.rights info:eu-repo/semantics/openAccess
dc.subject Lungnalæknisfræði
dc.subject Adult
dc.subject Humans
dc.subject Cough/complications
dc.subject Cross-Sectional Studies
dc.subject Pulmonary Disease, Chronic Obstructive
dc.subject Forced Expiratory Volume
dc.subject Vital Capacity
dc.subject Chronic Disease
dc.subject Occupations
dc.subject Dyspnea/epidemiology
dc.subject Pulmonary and Respiratory Medicine
dc.title Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.pmid 36028253
dc.identifier.doi https://doi.org/10.1183/13993003.00469-2022
dc.relation.url http://www.scopus.com/inward/record.url?scp=85146364403&partnerID=8YFLogxK
dc.contributor.department Faculty of Medicine
dc.contributor.department Internal Medicine and Emergency Services


Files in this item

This item appears in the following Collection(s)

Show simple item record