dc.contributor.author |
Jensen, Sanne |
dc.contributor.author |
Mortensen, Erik L. |
dc.contributor.author |
Skarphedinsson, Gudmundur |
dc.contributor.author |
Højgaard, David RMA |
dc.contributor.author |
Hybel, Katja A. |
dc.contributor.author |
Nissen, Judith B. |
dc.contributor.author |
Tord Ivarsson, Ivarsson |
dc.contributor.author |
Weidle, Bernhard |
dc.contributor.author |
Torp, Nor C. |
dc.contributor.author |
Thomsen, Per H. |
dc.date.accessioned |
2023-02-15T01:03:19Z |
dc.date.available |
2023-02-15T01:03:19Z |
dc.date.issued |
2022-11-01 |
dc.identifier.citation |
Jensen , S , Mortensen , E L , Skarphedinsson , G , Højgaard , D RMA , Hybel , K A , Nissen , J B , Tord Ivarsson , I , Weidle , B , Torp , N C & Thomsen , P H 2022 , ' Long- term remission status in pediatric obsessive-compulsive disorder : Evaluating the predictive value of symptom severity after treatment ' , Psychiatry Research , vol. 317 , 114906 , pp. 114906 . https://doi.org/10.1016/j.psychres.2022.114906 |
dc.identifier.issn |
0165-1781 |
dc.identifier.other |
67878862 |
dc.identifier.other |
096600f9-7c13-4c0a-9c8b-1b5759879adc |
dc.identifier.other |
85140658891 |
dc.identifier.other |
36265194 |
dc.identifier.other |
unpaywall: 10.1016/j.psychres.2022.114906 |
dc.identifier.uri |
https://hdl.handle.net/20.500.11815/3974 |
dc.description |
Funding Information: This work was supported by the Tryg Foundation [grant number 122892] and the Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry. Publisher Copyright: © 2022 The Author(s) |
dc.description.abstract |
It is unknown if long-term remission for pediatric obsessive-compulsive disorder (OCD) patients is associated with post-treatment OCD symptom severity. The aim of the present study was to evaluate if post-treatment symptom severity cut-offs can discriminate remitters from non-remitters in pediatric OCD patients during three years of follow-up. All participants (N = 269) from the Nordic Long-term OCD Treatment Study (NordLOTS) undergoing stepped-care treatment were included. Patients were rated with the Clinical Global Impression – Severity Scale (CGI-S) one (n = 186), two (n = 167), and three years (n = 166) after first-line cognitive-behavioral therapy. Post-treatment symptom severity scores as well as percentage reductions during treatment evaluated with the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) were analyzed using receiver operating characteristics according to the CGI-S remission scores (< 2) at follow-up. Post-treatment CY-BOCS severity scores acceptably discriminated remitters from non-remitters at one-year follow-up, but poorly for the two- and three-year follow-up. Severity percentage reduction during treatment did not discriminate remission status acceptably at any follow-up point. Post-treatment OCD symptom severity status seems to have little discriminative value for long-term remission status in pediatric patients. Further research is warranted to detect post-treatment factors of prognostic value. |
dc.format.extent |
500678 |
dc.format.extent |
114906 |
dc.language.iso |
en |
dc.relation.ispartofseries |
Psychiatry Research; 317() |
dc.rights |
info:eu-repo/semantics/openAccess |
dc.subject |
Children and adolescents |
dc.subject |
Children's Yale-brown obsessive-compulsive scale |
dc.subject |
Clinical assessment |
dc.subject |
Clinical global impression scale |
dc.subject |
Long-term study |
dc.subject |
Remission |
dc.subject |
Stepped-care treatment |
dc.subject |
Humans |
dc.subject |
Cognitive Behavioral Therapy |
dc.subject |
Obsessive-Compulsive Disorder/diagnosis |
dc.subject |
Child |
dc.subject |
Psychiatry and Mental Health |
dc.subject |
Biological Psychiatry |
dc.title |
Long- term remission status in pediatric obsessive-compulsive disorder : Evaluating the predictive value of symptom severity after treatment |
dc.type |
/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article |
dc.description.version |
Peer reviewed |
dc.identifier.doi |
10.1016/j.psychres.2022.114906 |
dc.relation.url |
http://www.scopus.com/inward/record.url?scp=85140658891&partnerID=8YFLogxK |
dc.contributor.department |
Faculty of Psychology |