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The Sound of Interconnectivity; The European Vasculitis Society 2022 Report

The Sound of Interconnectivity; The European Vasculitis Society 2022 Report


Title: The Sound of Interconnectivity; The European Vasculitis Society 2022 Report
Author: Egan, Allyson C.
Kronbichler, Andreas
Neumann, Irmgard
Bettiol, Alessandra
Carlson, Nicholas
Cid, Maria C.
Emmi, Giacomo
Gopaluni, Seerapani
Harper, Lorraine
Hauser, Thomas
... 22 more authors Show all authors
Date: 2022-08
Language: English
Scope: 13
Department: Internal Medicine and Emergency Services
Faculty of Medicine
Series: Kidney International Reports; 7(8)
ISSN: 2468-0249
DOI: https://doi.org/10.1016/j.ekir.2022.05.018
Subject: Gigtarlæknisfræði; clinical trials; genetics; histology; registries; vasculitis; Nephrology
URI: https://hdl.handle.net/20.500.11815/3854

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Citation:

Egan , A C , Kronbichler , A , Neumann , I , Bettiol , A , Carlson , N , Cid , M C , Emmi , G , Gopaluni , S , Harper , L , Hauser , T , Little , M A , Luqmani , R A , Mahr , A , McClure , M , Mohammad , A J , Nelveg-Kristensen , K E , Ohlsson , S , Peh , C A , Rutherford , M , Alamo , B S , Scott , J , Segelmark , M , Smith , R M , Szpirt , W M , Tómasson , G , Trivioli , G , Vaglio , A , Walsh , M , Wester Trejo , M , Westman , K , Bajema , I M & Jayne , D R W 2022 , ' The Sound of Interconnectivity; The European Vasculitis Society 2022 Report ' , Kidney International Reports , vol. 7 , no. 8 , pp. 1745-1757 . https://doi.org/10.1016/j.ekir.2022.05.018

Abstract:

The first European Vasculitis Society (EUVAS) meeting report was published in 2017. Herein, we report on developments in the past 5 years which were greatly influenced by the pandemic. The adaptability to engage virtually, at this critical time in society, embodies the importance of networks and underscores the role of global collaborations. We outline state-of-the-art webinar topics, updates on developments in the last 5 years, and proposals for agendas going forward. A host of newly reported clinical trials is shaping practice on steroid minimization, maintenance strategies, and the role of newer therapies. To guide longer-term strategies, a longitudinal 10-year study investigating relapse, comorbidity, malignancy, and survival rates is at an advanced stage. Disease assessment studies are refining classification criteria to differentiate forms of vasculitis more fully. A large international validation study on the histologic classification of anti-neutrophil cytoplasmic antibody (ANCA) glomerulonephritis, recruiting new multicenter sites and comparing results with the Kidney Risk Score, has been conducted. Eosinophilic granulomatosis with polyangiitis (EGPA) genomics offers potential pathogenic subset and therapeutic insights. Among biomarkers, ANCA testing is favoring immunoassay as the preferred method for diagnostic evaluation. Consolidated development of European registries is progressing with an integrated framework to analyze large clinical data sets on an unprecedented scale.

Description:

Funding Information: The authors acknowledge Dr. Elena Gelain (Nephrology Unit, Meyer Children's Hospital and Department of Biomedical Experimental and Clinical Sciences “Mario Serio,” University of Firenze, Firenze, Italy) for coordinating several EGPA and IgAV activities. EUVAS receives funding from Vifor Fresenius Medical Care Renal Pharma Ltd. Hoffman La Roche, InflaRx, and the charity Vasculitis UK. NC is supported by The Danish Heart Foundation. KENK was funded privately by Helen and Ejnar Bjørnows Foundation and Knud Højgaards Foundation. Funding Information: The authors acknowledge Dr. Elena Gelain (Nephrology Unit, Meyer Children’s Hospital and Department of Biomedical Experimental and Clinical Sciences “Mario Serio,” University of Firenze, Firenze, Italy) for coordinating several EGPA and IgAV activities. EUVAS receives funding from Vifor Fresenius Medical Care Renal Pharma Ltd., Hoffman La Roche, InflaRx, and the charity Vasculitis UK . NC is supported by The Danish Heart Foundation . KENK was funded privately by Helen and Ejnar Bjørnows Foundation and Knud Højgaards Foundation . Publisher Copyright: © 2022

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