Opin vísindi

Asthma, allergic rhinitis and atopic dermatitis in association with home environment - The RHINE study

Show simple item record

dc.contributor.author Wang, Juan
dc.contributor.author Janson, Christer
dc.contributor.author Malinovschi, Andrei
dc.contributor.author Holm, Mathias
dc.contributor.author Franklin, Karl A.
dc.contributor.author Modig, Lars
dc.contributor.author Johannessen, Ane
dc.contributor.author Schlünssen, Vivi
dc.contributor.author Gíslason, Þórarinn
dc.contributor.author Jogi, Nils Oskar
dc.contributor.author Norbäck, Dan
dc.date.accessioned 2022-12-16T01:03:46Z
dc.date.available 2022-12-16T01:03:46Z
dc.date.issued 2022-12-01
dc.identifier.citation Wang , J , Janson , C , Malinovschi , A , Holm , M , Franklin , K A , Modig , L , Johannessen , A , Schlünssen , V , Gíslason , Þ , Jogi , N O & Norbäck , D 2022 , ' Asthma, allergic rhinitis and atopic dermatitis in association with home environment - The RHINE study ' , Science of the Total Environment , vol. 853 , 158609 , pp. 158609 . https://doi.org/10.1016/j.scitotenv.2022.158609
dc.identifier.issn 0048-9697
dc.identifier.other PURE: 68696312
dc.identifier.other PURE UUID: 2a518125-7381-4134-b20d-66c80e58a8ef
dc.identifier.other unpaywall: 10.1016/j.scitotenv.2022.158609
dc.identifier.other Scopus: 85138034408
dc.identifier.uri https://hdl.handle.net/20.500.11815/3719
dc.description Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved. Funding Information: The work was supported by the Icelandic Research Council , the Swedish Heart and Lung Foundation , the Vårdal Foundation for Health Care and Allergic Research , the Swedish Association Against Asthma and Allergy , the Swedish Council for Work Life and Social Research , the Swedish AFA Insurance (No. 467801100 ), the Bror Hjerpstedt Foundation , the Norwegian Research Council , the Norwegian Asthma and Allergy Association , the Danish Lung Association and the Estonian Science Foundation . Publisher Copyright: © 2022
dc.description.abstract We studied home environment exposures in relation to asthma, allergic rhinitis and atopic dermatitis among offspring of participants (parents) in the Respiratory Health in Northern Europe (RHINE) study (age ≤ 30 y). Totally 17,881 offspring from Iceland, Norway, Sweden, Denmark and Estonia were included. Home environment exposures, including dampness and mold, type of dwelling, construction year and indoor painting were registered through a questionnaire answered by parents in the first follow up (RHINE II). The parents reported ten years later with in the frame of RHINE III offspring's birth year and offspring's asthma, allergic rhinitis, atopic dermatitis. They also reported dampness and mold at home from RHINE II to RHINE III. The prevalence of offspring's asthma before 10 y, asthma after 10 y, allergic rhinitis at any age and atopic dermatitis at any age were 9.7 %, 4.3 %, 15.6 % and 17.3 %, respectively. Asthma before 10 y was related to any indoor painting at RHINE II (OR = 1.14, 95%CI (1.02, 1.29)). Asthma after 10 y was associated with dampness/mold at home (OR = 1.33-1.62) and living in the newest buildings (constructed in 1986-2001) (OR = 1.30, 95%CI (1.02, 1.66)). Allergic rhinitis was associated with living in newer buildings (constructed in 1961-2001) (OR = 1.16-1.24). Atopic dermatitis was associated with visible mold (OR = 1.35, 95%CI(1.12, 1.62)), dampness/mold at home (OR = 1.18-1.38), living in apartments (OR = 1.22, 95%CI(1.10, 1.35)) and living in newer buildings (constructed in 1961-2001) (OR = 1.14-1.25). There were dose-response effects of dampness and mold on offspring's asthma after 10 y and atopic dermatitis (20 years exposure vs. 10 years exposure). Older offspring had increased risk of developing asthma after 10 y and atopic dermatitis. In conclusion, home dampness and mold, living in apartments, living in newer buildings and indoor painting were associated with offspring's asthma or allergic diseases. Stronger health effects were found among offspring with prolonged exposure of dampness/mold.
dc.format.extent 158609
dc.language.iso en
dc.relation.ispartofseries Science of the Total Environment; 853()
dc.rights info:eu-repo/semantics/openAccess
dc.subject Lungnalæknisfræði
dc.subject Humans
dc.subject Dermatitis, Atopic/epidemiology
dc.subject Home Environment
dc.subject Humidity
dc.subject Rhinitis, Allergic/epidemiology
dc.subject Asthma/epidemiology
dc.subject Fungi
dc.subject Europe
dc.subject Risk Factors
dc.subject Indoor painting
dc.subject Home environment
dc.subject Asthma
dc.subject Atopic dermatitis
dc.subject Allergic rhinitis
dc.subject Dampness
dc.subject Pollution
dc.subject Waste Management and Disposal
dc.subject Environmental Engineering
dc.subject Environmental Chemistry
dc.title Asthma, allergic rhinitis and atopic dermatitis in association with home environment - The RHINE study
dc.type /dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article
dc.description.version Peer reviewed
dc.identifier.pmid 36089044
dc.identifier.doi https://doi.org/10.1016/j.scitotenv.2022.158609
dc.relation.url http://www.scopus.com/inward/record.url?scp=85138034408&partnerID=8YFLogxK
dc.contributor.department Internal Medicine and Emergency Services

Files in this item

This item appears in the following Collection(s)

Show simple item record