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IRIS
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(2025)Background/Aims: Low-intervention clinical trials have been established under the European Union Clinical Trials Regulation (EU 536/2014) which aims to simplify the conduct of clinical trials with authorized medicinal products. There is limited experience ... -
Laminarins and their derivatives affect dendritic cell activation and their crosstalk with T cells (2025-05)This research explores the impact of structural variations in laminarins derived from seaweed on their immunomodulatory properties. Laminarins from Laminaria digitata, L. hyperborea, and Saccharina latissima, were obtained using a two-step water ...
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(2025-01-23)A novel bacterium, designated 19SA41, was isolated from the air of the Icelandic volcanic island Surtsey. Cells of strain 19SA41 are Gram-stain-negative, strictly aerobic, non-motile rods and form pale yellow-pigmented colonies. The strain grows at ...
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(2025-03)Background: Pneumococcal conjugate vaccines (PCVs) introduced in childhood national immunization programs lowered vaccine-type invasive pneumococcal disease (IPD), but replacement with non-vaccine-types persisted throughout the PCV10/13 follow-up period. ...
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(2025)Background: While medication is a recognized risk factor of delirium, there is currently a lack of detailed information on managing and preventing medication-induced cases. Aim: This review summarizes the information provided in neurology guidelines ...
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(2025-01-01)We investigate the design of magnetic ordering in one-dimensional mesoscopic magnetic Ising chains by modulating long-range interactions. These interactions are affected by geometrical modifications to the chain, which adjust the energy hierarchy and ...
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(2025)Introduction: Data regarding the incidence and outcomes of mismatch repair deficient (dMMR) rectal cancer is limited. This study characterizes dMMR rectal cancer patients, comparing response after neoadjuvant radiotherapy and oncological outcomes to ...
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(2025-04-15)Even though Bangkok is situated away from known active faults (about 150 km), due to the soft alluvial basin in and around the capital city of Thailand, several of these high-rise buildings experienced noticeable structural and non-structural responses ...
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(2025-02)Purpose: Fluoroquinolones are antibiotics associated with adverse events that prompted the European Medicines Agency to implement risk minimization measures (RMMs) in 2018/19 and 2020. Our aim is to assess the RMMs' impact on antibiotic prescriptions ...
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(2025-03-05)The natural bioactive products myxin and iodinin are phenazine 5,10-dioxides possessing potent anti-bacterial and anti-cancer activity in vitro. This work describes the synthesis and derivatization of new myxin and iodinin regioisomers, developed from ...
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(2025-01)Background: Diet significantly impacts the onset and progression of inflammatory bowel disease (IBD), and diet offers unique opportunities for treatment and preventative purposes. However, despite growing interest, no diet has been conclusively associated ...
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(2025-01)Background: Malnutrition predicts poor outcomes following hip fracture, affecting patient recovery, healthcare performance, and costs. Evidence-based guidelines recommend multicomponent, interdisciplinary nutrition care to improve intake, reduce ...
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(2025-01)Empirical studies worldwide show that warming has variable effects on plant litter decomposition, leaving the overall impact of climate change on decomposition uncertain. We conducted a meta-analysis of 109 experimental warming studies across seven ...
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(2025-04)Hydrologic research and operations make extensive use of streamflow time series. In most applications, these time series are estimated from rating curves, which relate flow to some easy-to-measure surrogate, typically stage. The conventional stage-discharge ...
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(Taylor and Francis Inc., 2025-01-01)This chapter argues that Barbie the film shows a critical awareness of current feminist and political issues, but the question remains about how it fares when it comes to critique of consumerism. If these issues are unexamined within the film, which ...
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(2025-05)Understanding the main drivers of behavioural disturbance in deep-diving cetaceans would improve predictions of anthropogenic noise effects on individual animals, habitats and populations. To investigate the potential roles of received level and source ...
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(2025-02-11)Background Adverse childhood experiences (ACEs) have been associated with increased risks of autoimmune diseases. However, data are scarce on the role of specific ACEs as well as the potential mediating role of adverse mental health symptoms in this ...
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(2025-03-30)Age-related macular degeneration and diabetic retinopathy are the main diseases that cause vision impairment. The standard treatment for this condition is the intravitreal injection of anti-vascular endothelial growth factor agents, which cause several ...
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(2025-03-03)Markmið þessarar rannsóknar er að öðlast innsýn í upplifanir kennara sem sinna hinsegin fræðslu gagnvart hinsegin bakslagi og hvort og þá hvernig það birtist þeim innan veggja skólans. Rannsóknin er eigindleg og aflað var gagna í gegnum fimm ...
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(2025-01)Objectives: This study aimed to investigate whether the apparent diffusion coefficient (ADC) maps values of breast lesions presenting as non-mass enhancement (NME) on MRI could predict benign or malignant pathohistological findings. Materials and ...