IRIS: Síðast bætt við

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    Exploratory Investigation of the Plasma Proteome Associated with the Endotheliopathy of Trauma 
    Krocker, Joseph D.; Lee, Kyung Hyun; Henriksen, Hanne H.; Wang, Yao Wei Willa; Schoof, Erwin M.; Karvelsson, Sigurdur T.; Rolfsson, Óttar; Johansson, P. I.; Pedroza, Claudia; Wade, Charles E. (2022-06-01)
    Background: The endotheliopathy of trauma (EoT) is associated with increased mortality following injury. Herein, we describe the plasma proteome related to EoT in order to provide insight into the role of the endothelium within the systemic response ...
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    Association between service readiness and PMTCT cascade effectiveness : a 2018 cross-sectional analysis from Manica province, Mozambique 
    Dinis, Aneth; Augusto, Orvalho; Ásbjörnsdóttir, Kristjana H.; Crocker, Jonny; Gimbel, Sarah; Inguane, Celso; Ramiro, Isaías; Coutinho, Joana; Agostinho, Mery; Cruz, Emilia; Amaral, Fernando; Tavede, Esperança; Isidoro, Xavier; Sidat, Yaesh; Nassiaca, Regina; Murgorgo, Filipe; Cuembelo, Fátima; Hazim, Carmen E.; Sherr, Kenneth (2022-11-28)
    Background: Despite high coverage of maternal and child health services in Mozambique, prevention of mother-to-child transmission of HIV (PMTCT) cascade outcomes remain sub-optimal. Delivery effectiveness is modified by health system preparedness. ...
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    Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study 
    Hedenstierna, Louise; Hedström, Anna Karin; Klareskog, Lars; Di Giuseppe, Daniela; Alfredsson, Lars; Askling, Johan; Ernestam, Sofia; Saevarsdottir, Saedis; Ljung, Lotta (2022-08-23)
    Objectives: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA). Methods: ...
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    Rate of SARS-CoV-2 Reinfection during an Omicron Wave in Iceland 
    Eythorsson, Elias; Runólfsdóttir, Hrafnhildur L.; Ingvarsson, Ragnar Freyr; Sigurðsson, Martin Ingi; Pálsson, Runólfur (2022-08-01)
    This cohort study estimates the proportion of persons who became reinfected with SARS-CoV-2 during the Omicron wave in Iceland.
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    Stafræn hæfni : Gagnsemi sjálfsmatsverkfæra og leiðarlykla í skólaþróun 
    Pétursdóttir, Svava; Þorsteinsdóttir, Þorbjörg St.; Jakobsdóttir, Sólveig (2022-11-12)
    Til að bregðast við breytingum sem fylgja stafrænni tækni og nýtingu hennar við nám og kennslu er í ýmsum stefnuskjölum lögð áhersla á hæfni kennara, starfsþróun og kennaramenntun. Evrópuráðið hefur sett fram ramma um stafræna hæfni í menntun (DigCompEdu ...
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    Antipsychotic use in pregnancy and risk of attention/deficit-hyperactivity disorder and autism spectrum disorder : a Nordic cohort study 
    Hálfdánarson, Óskar; Cohen, Jacqueline M.; Karlstad, Øystein; Cesta, Carolyn E.; Bjørk, Marte Helene; Håberg, Siri Eldevik; Einarsdóttir, Kristjana; Furu, Kari; Gissler, Mika; Hjellvik, Vidar; Kieler, Helle; Leinonen, Maarit K.; Nørgaard, Mette; Öztürk Essen, Buket; Ulrichsen, Sinna Pilgaard; Reutfors, Johan; Zoega, Helga (2022-05-01)
    BACKGROUND: Antipsychotics are increasingly used among women of childbearing age and during pregnancy. OBJECTIVE: To determine whether children exposed to antipsychotics in utero are at increased risk of attention-deficit/hyperactivity disorder (ADHD) ...
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    Prescription opioids among older adults : ten years of data across five countries 
    Hamina, A.; Muller, A. E.; Clausen, T.; Skurtveit, S.; Hesse, M.; Tjagvad, C.; Thylstrup, B.; Odsbu, I.; Zoega, H.; Jónsdóttir, Harpa Lind; Taipale, H. (2022-05-16)
    Abstract: Background: Opioid use has increased globally in the recent decade. Although pain remains a significant problem among older adults, susceptibility to opioid-related harms highlights the importance of careful opioid therapy monitoring on ...
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    Association of Maternal Autoimmune Diseases with Risk of Mental Disorders in Offspring in Denmark 
    He, Hua; Yu, Yongfu; Liew, Zeyan; Gissler, Mika; László, Krisztina D.; Valdimarsdóttir, Unnur Anna; Zhang, Jun; Li, Fei; Li, Jiong (2022-04-01)
    Importance: Maternal immune activation during pregnancy is associated with increased risks of several mental disorders in offspring during childhood, but little is known about how maternal autoimmune diseases during pregnancy are associated with mental ...
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    Neuroendocrine pathways and breast cancer progression : a pooled analysis of somatic mutations and gene expression from two large breast cancer cohorts 
    Hu, Kejia; Wang, Chengshi; Luo, Chuanxu; Zheng, Hong; Song, Huan; Bergstedt, Jacob; Fall, Katja; Luo, Ting; Czene, Kamila; Valdimarsdóttir, Unnur A.; Fang, Fang; Lu, Donghao (2022-06-21)
    Background: Experimental studies indicate that neuroendocrine pathways might play a role in progression of breast cancer. We aim to test the hypothesis that somatic mutations in the genes of neuroendocrine pathways influence breast cancer prognosis, ...
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    Perinatal mental health : how nordic data sources have contributed to existing evidence and future avenues to explore 
    Karalexi, Maria A.; Eberhard-Gran, Malin; Valdimarsdóttir, Unnur Anna; Karlsson, Hasse; Munk-Olsen, Trine; Skalkidou, Alkistis (2022-08)
    Purpose: Perinatal mental health disorders affect a significant number of women with debilitating and potentially life-threatening consequences. Researchers in Nordic countries have access to high quality, population-based data sources and the possibility ...
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    Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset 
    Sævarsdóttir, Sædís; Stefansdottir, Lilja; Sulem, P.; Thorleifsson, G.; Ferkingstad, E.; Rutsdottir, G.; Glintborg, B.; Westerlind, H.; Gröndal, Gerður María; Loft, I.C.; Sorensen, S.B.; Lie, B.A.; Brink, M.; Arlestig, L.; Arnthorsson, A.O.; Baecklund, E.; Banasik, K.; Bank, S.; Bjorkman, L.I.; Ellingsen, T.; Erikstrup, C.; Frei, O.; Gjertsson, I.; Gudbjartsson, D.F.; Gudjonsson, S.A.; Halldorsson, G.H.; Hendricks, O.; Hillert, J.; Hogdall, E.; Jacobsen, Sø; Jensen, D.V.; Jonsson, Helgi; Kastbom, A.; Kockum, I.; Kristensen, S.; Kristjansdottir, Helga; Larsen, M.H.; Linauskas, A.; Hauge, E.-M.; Loft, A.G.; Lúðvíksson, Björn Rúnar; Lund, S.H.; Markusson, Þorsteinn; Masson, G.; Melsted, P.; Moore, K.H.S.; Munk, H.; Nielsen, K.R.; Norddahl, G.L.; Oddsson, A.; Olafsdottir, T.A.; Olason, P.I.; Olsson, T.; Ostrowski, S.R.; Hørslev-Petersen, K.; Rognvaldsson, S.; Sanner, H.; Silberberg, G.N.; Stefansson, H.; Sørensen, E.; Sørensen, I.J.; Turesson, C.; Bergman, T.; Alfredsson, L.; Kvien, T.K.; Brunak, Sø; Steinsson, K.; Andersen, V.; Andreassen, O.A.; Rantapää-Dahlqvist, S.; Hetland, M.L.; Klareskog, L.; Askling, J.; Padyukov, L.; Pedersen, O.B.V.; Thorsteinsdottir, U.; Jonsdottir, I.; Stefánsson, Kári (2022-04-25)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
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    „Límdu saman heiminn minn“ : Ábyrgð stjórnvalda við að tryggja ungmennum velferðarþjónustu 
    Guðjohnsen, Ragný Þóra; Tórshamar, Telma Ýr (2022-09-16)
    Markmið rannsóknarinnar var að kalla eftir sýn ungs fólks sem glímir við vímuefnavanda á eigin neyslu og velferðarþjónustu sem þeim hefur staðið til boða frá barnsaldri. Tekin voru viðtöl við ellefu einstaklinga (18–25 ára). Í niðurstöðum kom fram að ...
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    A population-based meta-analysis of circulating GFAP for cognition and dementia risk 
    Gonzales, Mitzi M.; Wiedner, Crystal; Wang, Chen Pin; Liu, Qianqian; Bis, Joshua C.; Li, Zhiguang; Himali, Jayandra J.; Ghosh, Saptaparni; Thomas, Emy A.; Parent, Danielle M.; Kautz, Tiffany F.; Pase, Matthew P.; Aparicio, Hugo J.; Djoussé, Luc; Mukamal, Kenneth J.; Psaty, Bruce M.; Longstreth, William T.; Mosley, Thomas H.; Gudnason, Vilmundur; Mbangdadji, Djass; Lopez, Oscar L.; Yaffe, Kristine; Sidney, Stephen; Bryan, R. Nick; Nasrallah, Ilya M.; DeCarli, Charles S.; Beiser, Alexa S.; Launer, Lenore J.; Fornage, Myriam; Tracy, Russell P.; Seshadri, Sudha; Satizabal, Claudia L. (2022-09-03)
    Objective: Expression of glial fibrillary acidic protein (GFAP), a marker of reactive astrocytosis, colocalizes with neuropathology in the brain. Blood levels of GFAP have been associated with cognitive decline and dementia status. However, further ...
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    Germline variants of ATG7 in familial cholangiocarcinoma alter autophagy and p62 
    Greer, Stephanie U.; Chen, Jiamin; Ogmundsdottir, Margret H.; Ayala, Carlos; Lau, Billy T.; Delacruz, Richard Glenn C.; Sandoval, Imelda T.; Jones, David A.; Haslem, Derrick S.; Romero, Robin; Fulde, Gail; Bell, John M.; Jonasson, Jon G.; Steingrimsson, Eirikur; Ji, Hanlee P.; Nadauld, Lincoln D. (2022-06-20)
    Autophagy is a housekeeping mechanism tasked with eliminating misfolded proteins and damaged organelles to maintain cellular homeostasis. Autophagy deficiency results in increased oxidative stress, DNA damage and chronic cellular injury. Among the core ...
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    Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours : a consensus statement 
    Boguszewski, Margaret C.S.; Boguszewski, Cesar L.; Chemaililly, Wassim; Cohen, Laurie E.; Gebauer, Judith; Higham, Claire; Hoffman, Andrew R.; Polak, Michel; Yuen, Kevin C.J.; Alos, Nathalie; Antal, Zoltan; Bidlingmaier, Martin; Biller, Beverley M.K.; Brabant, George; Choong, Catherine S.Y.; Cianfarani, Stefano; Clayton, Peter E.; Coutant, Regis; Cardoso-Demartini, Adriane A.; Fernandez, Alberto; Grimberg, Adda; Guðmundsson, Kolbeinn; Guevara-Aguirre, Jaime; K Y Ho, Ken; Horikawa, Reiko; Isidori, Andrea M.; Otto Lunde Jørgensen, Jens; Kamenicky, Peter; Karavitaki, Niki; Kopchick, John J.; Lodish, Maya; Luo, Xiaoping; McCormack, Ann I.; Meacham, Lillian; Melmed, Shlomo; Moab, Sogol Mostoufi; Müller, Hermann L.; Neggers, Sebastian J.C.M.M.; Aguiar Oliveira, Manoel H.; Ozono, Keiichi; Pennisi, Patricia A.; Popovic, Vera; Radovick, Sally; Savendahl, Lars; Touraine, Philippe; van Santen, Hanneke M.; Johannsson, Gudmundur (2022-06)
    Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been studied extensively. Experimental studies showing the permissive role of GH/insulin-like growth factor 1 (IGF-I) in carcinogenesis have raised concerns regarding ...
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    Einelti og líðan starfsfólks sveitarfélaga á tímum efnahagsþrenginga 
    Sigursteinsdóttir, Hjördís (2013)
    Markmið þessarar rannsóknar er að skoða einelti og líðan á vinnustað meðal starfsfólks sveitarfélaga í kjölfar efnahagshrunsins hér á landi 2008. Rafrænn spurningalisti var í þrígang lagður fyrir starfsfólk 20 sveitarfélaga með þekkt netfang, fyrst í ...
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    Hvernig gengur leikskólakennurum og grunnskólakennurum að samræma vinnu og einkalíf? 
    Sigursteinsdóttir, Hjördís (2022-08-04)
    Almenn vellíðan fylgir því að ráða við daglegar áskoranir í lífinu, svo sem að geta haldið jafnvægi milli þeirra ólíku hlutverka sem við gegnum daglega. Markmið þessarar rannsóknar var að skoða hvernig leikskólakennurum og grunnskólakennurum gengi að ...
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    Alþjóðlegur bakgrunnur, skólasókn og brotthvarf úr íslenskum framhaldsskólum 2001-2021 
    Garðarsdóttir, Ólöf; Rúnarsdóttir, Eyrún María; Hauksson, Guðjón (2022-12-13)
    Jón Torfi Jónasson hefur á ferli sínum dregið fram hið lítt öfundsverða hlutskipti íslenskra framhaldskólanema sem birtist í miklu brotthvarfi þeirra frá námi. Í þessari rannsókn er sjónum beint að framhaldsskólasókn, þar sem kannaðar eru líkur á því ...
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    Health-Related Physical Fitness in Adolescents from Spain, Estonia and Iceland : A Cross-Sectional, Quantitative Study 
    Galan-Lopez, Pablo; Gísladóttir, Thordis; Pihu, Maret; Sánchez-Oliver, Antonio J.; Ries, Francis; Domínguez, Raúl (2022-11-22)
    The benefits of physical fitness (PF) for health are well-known. Low PF significantly contributes to the prevalence of obesity in adolescents, with an increased risk of developing chronic diseases. The objectives of the present study were to explore ...
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    Samanburður á upplifun starfsmanna einkarekinna fyrirtækja og starfsmanna hins opinbera af vinnustað og starfi 
    Kristbergsdóttir, Hlín; Hafsteinsson, Leifur Geir; Einarsdóttir, Arney (2008)
    Alþekkt er að vinnuumhverfi hins opinbera og einkageirans er ólíkt á allmörgum sviðum. Megintilgangur þessarar rannsóknar var að bera saman upplifun starfsfólks í einkareknum fyrirtækjum og hjá opinberum stofnunum á ýmsum vinnusálfræðilegum þáttum. ...