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Browsing IRIS by Subject "Lyfjameðferð"

Now showing items 1-8 of 8

Árangur ADHD-lyfjameðferðar fullorðinna í ADHD-teymi Landspítala 2015-2017

Sigurðsson, Engilbert; Bjarnadottir , S.; Olafsdottir, H.; Johnsen , A.; Haraldsson , M.; Kjartansdottir , S. H. (2020-03)

Background: Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder among children but symptoms may persist into adulthood. At Landspitali - the National University Hospital an interdisciplinary unit is responsible ...
Cognitive-behavioural therapy in medication-treated adults with attention-deficit/hyperactivity disorder and co-morbid psychopathology: a randomized controlled trial using multi-level analysis.

Young, S; Khondoker, M; Emilsson, Brynjar; Sigurðsson, Jón F; Philipp-Wiegmann, F.; Baldursson, Gísli; Olafsdottir, Halldora; Gudjonsson, Gisli H. (2015-05-29)

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by high rates of co-morbid psychopathology. Randomized controlled trials of multimodal interventions, combining pharmacological and psychological treatments, ...
Effectiveness and treatment retention of TNF inhibitors when used as monotherapy versus comedication with csDMARDs in 15 332 patients with psoriatic arthritis. Data from the EuroSpA collaboration

Lindström, Ulf; Di Giuseppe, Daniela; Delcoigne, Bénédicte; Glintborg, Bente; Möller, Burkhard; Ciurea, Adrian; Pombo-Suarez, Manuel; Sanchez-Piedra, Carlos; Eklund, Kari; Relas, Heikki; Guðbjörnsson, Björn; Löve, Þorvarður Jón; Jones, Gareth T.; Codreanu, Catalin; Ionescu, Ruxandra; Nekvindova, Lucie; Závada, Jakub; Atas, Nuh; Yolbas, Servet; Fagerli, Karen Minde; Michelsen, Brigitte; Rotar, Ziga; Tomšič, Matija; Iannone, Florenzo; Santos, Maria Jose; Avila-Ribeiro, Pedro; Ørnbjerg, Lykke Midtbøll; Østergaard, Mikkel; Jacobsson, Lennart T.H.; Askling, Johan; Nissen, Michael J. (2021-06-03)

Background Comedication with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) during treatment with tumour necrosis factor inhibitors (TNFi) is extensively used in psoriatic arthritis (PsA), although the additive benefit remains ...
A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma

Liu, Xiaoyan; Swen, Jesse J.; Diekstra, Meta H.M.; Boven, Epie; Castellano, Daniel; Gelderblom, Hans; Mathijssen, Ron H.J.; Vermeulen, Sita H.; Oosterwijk, Egbert; Junker, Kerstin; Roessler, Max; Alexiusdottir, Kristin; Sverrisdóttir, Ásgerður; Radu, Marius T.; Ambert, Valentin; Eisen, Tim; Warren, Anne; Rodríguez-Antona, Cristina; García-Donas, Jesus; Böhringer, Stefan; Koudijs, Karel K.M.; Kiemeney, Lambertus A.L.M.; Rini, Brian I.; Guchelaar, Henk-Jan (2018-05-15)

Purpose: The survival of patients with clear cell metastatic renal cell carcinoma (cc-mRCC) has improved substantially since the introduction of tyrosine kinase inhibitors (TKI). With the fact that TKIs interact with immune responses, we investigated ...
HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry

Konte, Bettina; Walters, James T.R.; Rujescu, Dan; Legge, Sophie E.; Pardiñas, Antonio F.; Cohen, Dan; Pirmohamed, Munir; Tiihonen, Jari; Hartmann, Annette M.; Bogers, Jan P.; van der Weide, Jan; van der Weide, Karen; Putkonen, Anu; Repo-Tiihonen, Eila; Hallikainen, Tero; Silva, Ed; Ingimarsson, Oddur; Sigurðsson, Engilbert; Kennedy, James L.; Sullivan, Patrick F.; Rietschel, Marcella; Breen, Gerome; Stefansson, Hreinn; Stefansson, Kari; Collier, David A.; O’Donovan, Michael C.; Giegling, Ina (2021-04-12)

The atypical antipsychotic clozapine is the only effective medication for treatment-resistant schizophrenia. However, it can also induce serious adverse drug reactions, including agranulocytosis and neutropenia. The mechanism by which it does so is ...
Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial

Stockfelt, Marit; Lundell, Anna Carin; Hetland, Merete Lund; Østergaard, Mikkel; Uhlig, Till; Heiberg, Marte Schrumpf; Haavardsholm, Espen A.; Nurmohamed, Michael T.; Lampa, Jon; Nordström, Dan; Petersen, Kim Hørslev; Guðbjörnsson, Björn; Gröndal, Gerður; Aldridge, Jonathan; Andersson, Kerstin; Blennow, Kaj; Zetterberg, Henrik; van Vollenhoven, Ronald; Rudin, Anna (2021-07-13)

Background: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics ...
Töflur og töflugerð. Með sérstöku tilliti til íslenskra aðstæðna.

Skaftason, Jóhannes F; Jóhannesson, Þorkell (2013-04)

Töfluslátta hófst í Englandi 1844. Fyrstu töflur innihéldu vatnsleysin sölt samkvæmt forskrift Brockedons og voru sennilega slegnar án hjálparefna. Tímamót urðu um 1887 þegar tekið var að nota mjölva (amylum maydis) í Bandaríkjunum til þess að sundra ...
Þættir sem hafa áhrif á ákvörðun lækna um lyfjameðferð : Rannsókn í heilsugæslu á Íslandi

Ivarsdottir, Yrsa; Jónsson, Jón Steinar; Linnet, Kristjan; Blöndal, Anna Bryndís (2021-11-01)

INTRODUCTION: This study aimed to analyse several factors that influence the decision-making of primary care physicians in Iceland in their choice of drug therapy for their patients. Also, to find which factors can act as a hindrance in making the best ...

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