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    Association of female sex and positive rheumatoid factor with low serum infliximab and anti-drug antibodies, related to treatment failure in early rheumatoid arthritis : results from the SWEFOT trial population 
    for the SWEFOT study group (2019-09-03)
    Objective: Infliximab-treated patients with rheumatoid arthritis (RA) may respond insufficiently due to low serum infliximab (sIFX) levels, caused by anti-drug antibodies (ADAs). However, monitoring of sIFX and ADAs is not routinely implemented, and ...
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    The association of living donor source with patient and graft survival among kidney transplant recipients in the ERA-EDTA Registry – a retrospective study 
    Abd ElHafeez, Samar; Noordzij, Marlies; Kramer, Anneke; Bell, Samira; Savoye, Emilie; Abad Diez, José Maria; Lundgren, Torbjörn; Reisæter, Anna Varberg; Kerschbaum, Julia; Santiuste de Pablos, Carmen; Ortiz, Fernanda; Collart, Frederic; Pálsson, Runólfur; Arici, Mustafa; Heaf, James G.; Massy, Ziad A.; Jager, Kitty J. (2020-10-06)
    In this study we aimed to compare patient and graft survival of kidney transplant recipients who received a kidney from a living-related donor (LRD) or living-unrelated donor (LUD). Adult patients in the ERA-EDTA Registry who received their first kidney ...
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    Association of low-frequency and rare coding variants with information processing speed 
    Bressler, Jan; Davies, Gail; Smith, Albert Vernon; Saba, Yasaman; Bis, Joshua C.; Jian, Xueqiu; Hayward, Caroline; Yanek, Lisa; Smith, Jennifer A.; Mirza, Saira S.; Wang, Ruiqi; Adams, Hieab H.H.; Becker, Diane; Boerwinkle, Eric; Campbell, Archie; Cox, Simon R.; Eiríksdóttir, Guðný; Fawns-Ritchie, Chloe; Gottesman, Rebecca F.; Grove, Megan L.; Guo, Xiuqing; Hofer, Edith; Kardia, Sharon L.R.; Knol, Maria J.; Koini, Marisa; Lopez, Oscar L.; Marioni, Riccardo E.; Nyquist, Paul; Pattie, Alison; Polasek, Ozren; Porteous, David J.; Rudan, Igor; Satizabal, Claudia L.; Schmidt, Helena; Schmidt, Reinhold; Sidney, Stephen; Simino, Jeannette; Smith, Blair H.; Turner, Stephen T.; van der Lee, Sven J.; Ware, Erin B.; Whitmer, Rachel A.; Yaffe, Kristine; Yang, Qiong; Zhao, Wei; Guðnason, Vilmundur G.; Launer, Lenore J.; Fitzpatrick, Annette L.; Psaty, Bruce M.; Fornage, Myriam; Arfan Ikram, M.; van Duijn, Cornelia M.; Seshadri, Sudha; Mosley, Thomas H.; Deary, Ian J. (2021-12-04)
    Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare ...
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    Association of Maternal Autoimmune Diseases with Risk of Mental Disorders in Offspring in Denmark 
    He, Hua; Yu, Yongfu; Liew, Zeyan; Gissler, Mika; László, Krisztina D.; Valdimarsdóttir, Unnur Anna; Zhang, Jun; Li, Fei; Li, Jiong (2022-04-01)
    Importance: Maternal immune activation during pregnancy is associated with increased risks of several mental disorders in offspring during childhood, but little is known about how maternal autoimmune diseases during pregnancy are associated with mental ...
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    Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study. 
    Jakubowska, A; Rozkrut, D; Antoniou, A; Hamann, U; Scott, R J; McGuffog, L; Healy, S; Sinilnikova, O M; Rennert, G; Lejbkowicz, F; Flugelman, A; Andrulis, I L; Glendon, G; Ozcelik, H; Thomassen, M; Paligo, M; Aretini, P; Kantala, J; Aroer, B; von Wachenfeldt, A; Liljegren, A; Loman, N; Herbst, K; Kristoffersson, U; Rosenquist, R; Karlsson, P; Stenmark-Askmalm, M; Melin, B; Nathanson, K L; Domchek, S M; Byrski, T; Huzarski, T; Gronwald, J; Menkiszak, J; Cybulski, C; Serrano, P; Osorio, A; Cajal, T R; Tsitlaidou, M; Benítez, J; Gilbert, M; Rookus, M; Aalfs, C M; Kluijt, I; Boessenkool-Pape, J L; Meijers-Heijboer, H E J; Oosterwijk, J C; van Asperen, C J; Blok, M J; Nelen, M R; van den Ouweland, A M W; Seynaeve, C; van der Luijt, R B; Devilee, P; Easton, D F; Peock, S; Frost, D; Platte, R; Ellis, S D; Fineberg, E; Evans, D G; Lalloo, F; Eeles, R; Jacobs, C; Adlard, J; Davidson, R; Eccles, D; Cole, T; Cook, J; Godwin, A; Bove, B; Stoppa-Lyonnet, D; Caux-Moncoutier, V; Belotti, M; Tirapo, C; Mazoyer, S; Barjhoux, L; Boutry-Kryza, N; Pujol, P; Coupier, I; Peyrat, J-P; Vennin, P; Muller, D; Fricker, J-P; Venat-Bouvet, L; Jóhannsson, Óskar Þór; Isaacs, C; Schmutzler, R; Wappenschmidt, B; Meindl, A; Arnold, N; Varon-Mateeva, R; Niederacher, D; Sutter, C; Deissler, H; Preisler-Adams, S; Simard, J; Soucy, P; Durocher, F; Chenevix-Trench, G; Beesley, J; Chen, X; Rebbeck, T; Couch, F; Wang, X; Lindor, N; Fredericksen, Z; Pankratz, V S; Peterlongo, P; Bonanni, B; Fortuzzi, S; Peissel, B; Szabo, C; Mai, P L; Loud, J T; Lubinski, J (2012-06-05)
    The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that other genetic or environmental factors modify breast cancer risk. Two genes of special interest are prohibitin (PHB) and methylene-tetrahydrofolate reductase (MTHFR), ...
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    Association of Prenatal Exposure to Antiseizure Medication with Risk of Autism and Intellectual Disability 
    Bjørk, Marte Helene; Zoega, Helga; Leinonen, Maarit K.; Cohen, Jacqueline M.; Dreier, Julie Werenberg; Furu, Kari; Gilhus, Nils Erik; Gissler, Mika; Hálfdánarson, Óskar; Igland, Jannicke; Sun, Yuelian; Tomson, Torbjörn; Alvestad, Silje; Christensen, Jakob (2022-07-01)
    Importance: Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to AMSs is uncertain. Objective: To determine whether children exposed prenatally ...
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    Association of respiratory symptoms and lung function with occupation in the multinational Burden of Obstructive Lung Disease (BOLD) study 
    BOLD Collaborative Research Group (2023-01)
    BACKGROUND: Chronic obstructive pulmonary disease has been associated with exposures in the workplace. We aimed to assess the association of respiratory symptoms and lung function with occupation in the Burden of Obstructive Lung Disease study. METHODS: ...
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    Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39 
    Spiliopoulou, Athina; Colombo, Marco; Plant, Darren; Nair, Nisha; Cui, Jing; Coenen, Marieke J.H.; Ikari, Katsunori; Yamanaka, Hisashi; Saevarsdottir, Saedis; Padyukov, Leonid; Bridges, S. Louis; Kimberly, Robert P.; Okada, Yukinori; Van Riel, Piet L.C.M.; Wolbink, Gertjan; Van Der Horst-Bruinsma, Irene E.; De Vries, Niek; Tak, Paul P.; Ohmura, Koichiro; Canhão, Helena; Guchelaar, Henk Jan; Huizinga, Tom W.J.; Criswell, Lindsey A.; Raychaudhuri, Soumya; Weinblatt, Michael E.; Wilson, Anthony G.; Mariette, Xavier; Isaacs, John D.; Morgan, Ann W.; Pitzalis, Costantino; Barton, Anne; Mckeigue, Paul (2019-08-01)
    Objectives We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these ...
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    The association of spirometric small airways obstruction with respiratory symptoms, cardiometabolic diseases, and quality of life : results from the Burden of Obstructive Lung Disease (BOLD) study 
    Knox-Brown, Ben; Patel, Jaymini; Potts, James; Ahmed, Rana; Aquart-Stewart, Althea; Barbara, Cristina; Buist, A. Sonia; Cherkaski, Hamid Hacene; Denguezli, Meriam; Elbiaze, Mohammed; Erhabor, Gregory E.; Franssen, Frits M.E.; Al Ghobain, Mohammed; Gíslason, Þórarinn; Janson, Christer; Kocabaş, Ali; Mannino, David; Marks, Guy; Mortimer, Kevin; Nafees, Asaad Ahmed; Obaseki, Daniel; Paraguas, Stefanni Nonna M.; Loh, Li Cher; Rashid, Abdul; Salvi, Sundeep; Seemungal, Terence; Studnicka, Michael; Tan, Wan C.; Wouters, Emiel F.M.; Abozid, Hazim; Mueller, Alexander; Burney, Peter; Amaral, Andre F.S. (2023-05-23)
    Background: Spirometric small airways obstruction (SAO) is common in the general population. Whether spirometric SAO is associated with respiratory symptoms, cardiometabolic diseases, and quality of life (QoL) is unknown. Methods: Using data from the ...
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    Association of stress-related disorders with subsequent risk of all-cause and cause-specific mortality : A population-based and sibling-controlled cohort study 
    Tian, Fan; Shen, Qing; Hu, Yihan; Ye, Weimin; Valdimarsdóttir, Unnur A.; Song, Huan; Fang, Fang (2022-07)
    Background: Prior research provides suggestive evidence on an association between stress-related disorders and mortality. No previous study has however addressed the role of familial confounding on such association. Methods: We conducted a nationwide ...
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    Associations between antimicrobial susceptibility/resistance of Neisseria gonorrhoeae isolates in European Union/European Economic Area and patients’ gender, sexual orientation and anatomical site of infection, 2009–2016 
    on behalf of The Euro-GASP Network (2021-03-18)
    BACKGROUND: The emergence and spread of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, nationally and internationally, is a serious threat to the management and control of gonorrhoea. Limited and conflicting data regarding the epidemiological ...
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    Associations between new-onset postoperative atrial fibrillation and long-term outcome in patients undergoing surgical aortic valve replacement 
    Rezk, Mary; Taha, Amar; Nielsen, Susanne J; Martinsson, Andreas; Bergfeldt, Lennart; Guðbjartsson, Tómas; Franzén, Stefan; Jeppsson, Anders (2023-05-02)
    OBJECTIVES: Data on prognostic implications of new-onset postoperative atrial fibrillation (POAF) after surgical aortic valve replacement (SAVR) is limited. We sought to explore associations between POAF, early initiated oral anticoagulation (OAC) and ...
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    Associations of parental and perinatal factors with subsequent risk of stress-related disorders : a nationwide cohort study with sibling comparison 
    Li, Yuchen; Sjölander, Arvid; Song, Huan; Cnattingius, Sven; Fang, Fang; Yang, Qian; Fernández de la Cruz, Lorena; Mataix-Cols, David; Brander, Gustaf; Li, Jiong; Zhang, Wei; Fall, Katja; D’Onofrio, Brian M.; Almqvist, Catarina; Lichtenstein, Paul; Valdimarsdóttir, Unnur Anna; Lu, Donghao (2022-01-01)
    Little is known about the contribution of pregnancy-related parental and perinatal factors to the development of stress-related disorders. We aimed to investigate whether parental/perinatal adversities entail higher risks of stress-related disorders ...
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    Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia : longitudinal data of the AGES-Reykjavik Study 
    van Gennip, April C.E.; Satizabal, Claudia L.; Tracy, Russell P.; Sigurdsson, Sigurdur; Gudnason, Vilmundur; Launer, Lenore J.; van Sloten, Thomas T. (2023-08-02)
    We investigated the associations of plasma neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and total tau (t-tau) with markers of cerebral small vessel disease (SVD) and with incident dementia. We also investigated whether associations ...
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    Associations of Pulmonary Function with MRI Brain Volumes : A Coordinated Multi-Study Analysis 
    Frenzel, Stefan; Bis, Joshua C.; Gudmundsson, Elias F.; O'Donnell, Adrienne; Simino, Jeannette; Yaqub, Amber; Bartz, Traci M.; Brusselle, Guy G.O.; Bülow, Robin; DeCarli, Charles S.; Ewert, Ralf; Gharib, Sina A.; Ghosh, Saptaparni; Gireud-Goss, Monica; Gottesman, Rebecca F.; Ikram, M. Arfan; Knopman, David S.; Launer, Lenore J.; London, Stephanie J.; Longstreth, W. T.; Lopez, Oscar L.; Melo van Lent, Debora; O'Connor, George; Satizabal, Claudia L.; Shrestha, Srishti; Sigurdsson, Sigurdur; Stubbe, Beate; Talluri, Rajesh; Vasan, Ramachandran S.; Vernooij, Meike W.; Völzke, Henry; Wiggins, Kerri L.; Yu, Bing; Beiser, Alexa S.; Gudnason, Vilmundur; Mosley, Thomas; Psaty, Bruce M.; Wolters, Frank J.; Grabe, Hans J.; Seshadri, Sudha (2022-11-22)
    BACKGROUND: Previous studies suggest poor pulmonary function is associated with increased burden of cerebral white matter hyperintensities and brain atrophy among elderly individuals, but the results are inconsistent. OBJECTIVE: To study the cross-sectional ...
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    Asthma, allergic rhinitis and atopic dermatitis in association with home environment - The RHINE study 
    Wang, Juan; Janson, Christer; Malinovschi, Andrei; Holm, Mathias; Franklin, Karl A.; Modig, Lars; Johannessen, Ane; Schlünssen, Vivi; Gíslason, Þórarinn; Jogi, Nils Oskar; Norbäck, Dan (2022-12-01)
    We studied home environment exposures in relation to asthma, allergic rhinitis and atopic dermatitis among offspring of participants (parents) in the Respiratory Health in Northern Europe (RHINE) study (age ≤ 30 y). Totally 17,881 offspring from Iceland, ...
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    Asymmetric Phenyl Substitution : An Effective Strategy to Enhance the Photosensitizing Potential of Curcuminoids 
    Vesco, Guglielmo; Brambati, Martino; Scapinello, Luca; Penoni, Andrea; Mella, Massimo; Masson, Màr; Gaware, Vivek; Maspero, Angelo; Nardo, Luca (2022-07-09)
    Curcumin has been demonstrated to exhibit photosensitized bactericidal activity. However, the full exploitation of curcumin as a photo-pharmaceutical active principle is hindered by fast deactivation of the excited state through the transfer of the ...
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    Asymmetric Synthesis of Methoxylated Ether Lipids : Total Synthesis of Polyunsaturated C18:3 Omega-3 and Omega-6 MEL Triene Derivatives 
    Sigurjónsson, Svanur; Haraldsson, Gudmundur G. (2024-01)
    The asymmetric synthesis of polyunsaturated triene C18:3 n-3 and C18:3 n-6 methoxylated ether lipids (MEL) of the 1-O-alkyl-sn-glycerol type is described as possible structural candidates for a triene C18:3 MEL of an unknown identity found in a mixture ...
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    Athyglisbrestur og ofvirkni – of eða van? 
    Bjarnadóttir, Guðrún Dóra (2020-03-04)
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    Atomoxetine in Early Pregnancy and the Prevalence of Major Congenital Malformations : A Multinational Study 
    Bröms, Gabriella; Hernandez-Diaz, Sonia; Huybrechts, Krista F.; Bateman, Brian T.; Kristiansen, Eskild Bendix; Einarsdóttir, Kristjana; Engeland, Anders; Furu, Kari; Gissler, Mika; Karlsson, Pär; Klungsøyr, Kari; Lahesmaa-Korpinen, Anna Maria; Mogun, Helen; Nørgaard, Mette; Reutfors, Johan; Sørensen, Henrik Toft; Zoega, Helga; Kieler, Helle (2023-01-16)
    Objective: Most research on safety of attention-deficit/hyperactivity disorder (ADHD) medications during pregnancy concerns central nervous system stimulants, while little is known about the safety of atomoxetine, a primary treatment alternative. We ...