Anand, Amitesh; Olson, Connor A.; Sastry, Anand V.; Patel, Arjun; Szubin, Richard; Yang, Laurence; Feist, Adam M.; Pálsson, Bernhard Örn
(2021-04-01)
Pyruvate dehydrogenase complex (PDC) functions as the main determinant of the respiro-fermentative balance because it converts pyruvate to acetyl-coenzyme A (CoA), which then enters the TCA (tricarboxylic acid cycle). PDC is repressed by the pyruvate ...