Browsing IRIS by Author "Eysteinsson, Thor"

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Membrane Permeability Is Required for the Vasodilatory Effect of Carbonic Anhydrase Inhibitors in Porcine Retinal Arteries

Eysteinsson, Thor; García-Llorca, Andrea; Hardarson, Arnar Oessur; Vullo, Daniela; Carta, Fabrizio; Supuran, Claudiu T. (2023-05-02)

It has been demonstrated previously that a variety of carbonic anhydrase inhibitors (CAIs) can induce vasodilation in pre-contracted retinal arteriolar segments although with different efficacy and potency. Since the CAIs tested so far are able to ...
Mouse microphthalmia-associated transcription factor (Mitf) mutations affect the structure of the retinal vasculature

Daníelsson, Stefán Broddi; García-Llorca, Andrea; Reynisson, Hallur; Eysteinsson, Thor (2022-03-29)

Purpose: Mice carrying pathogenic variants in the microphthalmia transcription factor (Mitf) gene show structural and functional changes in the retina and retinal pigment epithelium. The purpose of this study was to assess the vascular changes in Mitf ...

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