IRIS: Recent submissions

  • Su, Guobin; Song, Huan; Lanka, Vivekananda; Liu, Xusheng; Fang, Fang; Valdimarsdóttir, Unnur A.; Carrero, Juan Jesus (2021-03)
    Introduction: Stress related disorders (SRDs, i.e., psychiatric disorders induced by significant life stressors) increase vulnerability to health problems. Whether SRDs associate with risk of acute kidney injury (AKI) and chronic kidney disease (CKD) ...
  • Smaradottir, Maria Isabel; Andersen, Karl; Gudnason, Vilmundur; Näsman, Per; Rydén, Lars; Mellbin, Linda Garcia (2021-07)
    BACKGROUND: Elevated copeptin, a marker for vasopressin release, has been associated with impaired prognosis in acute myocardial infarction (MI). The aim was to investigate whether this association extends beyond the acute phase and whether it is related ...
  • Thórsson, Bolli; Guðmundsson, Elías Freyr; Sigurðsson, Gunnar; Aspelund, Thor; Guðnason, Vilmundur G. (2021-05)
    INNGANGUR Fjöldi fólks með sykursýki 2 hefur vaxið undanfarna áratugi á Íslandi. Í þessari rannsókn var notaður Lyfjagagnagrunnur Embættis landlæknis til að meta algengi og nýgengi sykursýki 2 og sett fram spá um algengi sykursýki 2 eftir 10 og 20 ár. ...
  • van Lier, Lisanne I.; van der Roest, Henriëtte G.; Garms-Homolová, Vjenka; Onder, Graziano; Jónsson, Pálmi V.; Declercq, Anja; Hertogh, Cees M.P.M.; van Hout, Hein P.J.; Bosmans, Judith E. (2021-06)
    This study aims to benchmark mean societal costs per client in different home care models and to describe characteristics of home care models with the lowest societal costs. In this prospective longitudinal study in 6 European countries, 6-month societal ...
  • Skuladottir, Astros Th; Bjornsdottir, Gyda; Thorleifsson, Gudmar; Walters, G. Bragi; Nawaz, Muhammad Sulaman; Moore, Kristjan Helgi Swerford; Olason, Pall I.; Thorgeirsson, Thorgeir E.; Sigurpalsdottir, Brynja; Sveinbjornsson, Gardar; Eggertsson, Hannes P.; Magnusson, Sigurdur H.; Oddsson, Asmundur; Bjornsdottir, Anna; Vikingsson, Arnor; Sveinsson, Olafur A.; Hrafnsdottir, Maria G.; Sigurdardottir, Gudrun R.; Halldorsson, Bjarni V.; Hansen, Thomas Folkmann; Paarup, Helene; Erikstrup, Christian; Nielsen, Kaspar; Klokker, Mads; Bruun, Mie Topholm; Sorensen, Erik; Banasik, Karina; Burgdorf, Kristoffer S.; Pedersen, Ole Birger; Ullum, Henrik; Jonsdottir, Ingileif; Stefansson, Hreinn; Stefansson, Kari (2021-02-18)
    Bell’s palsy is the most common cause of unilateral facial paralysis and is defined as an idiopathic and acute inability to control movements of the facial muscles on the affected side. While the pathogenesis remains unknown, previous studies have ...
  • Snook, Abigail Grover; Schram, Asta B.; Jones, Brett D. (2021-03-29)
    Background: It is uncommon for faculty development professionals to assess faculty attitudes towards their teaching responsibilities and their perceived obstacles to teaching effectiveness. The purposes of this study were (a) to document faculty attitudes ...
  • Halldórsson, Þórhallur Ingi; Birgisdóttir, Bryndís Eva; Brantsæter, Anne Lise; Meltzer, Helle Margrete; Haugen, Margaretha; Þórsdóttir, Inga; Ólafsdóttir, Anna Sigríður; Olsen, Sjurdur F. (2021-01-29)
    BACKGROUND: A previous randomized dietary intervention in pregnant women from the 1970s, the Harlem Trial, reported retarded fetal growth and excesses of very early preterm births and neonatal deaths among those receiving high-protein supplementation. ...
  • Kohnke, Sara; Buller, Sophie; Nuzzaci, Danae; Ridley, Katherine; Lam, Brian; Pivonkova, Helena; Bentsen, Marie A.; Alonge, Kimberly M.; Zhao, Chao; Tadross, John; Holmqvist, Staffan; Shimizo, Takahiro; Hathaway, Hannah; Li, Huiliang; Macklin, Wendy; Schwartz, Michael W.; Richardson, William D.; Yeo, Giles S.H.; Franklin, Robin J.M.; Káradóttir, Ragnhildur Þóra; Rowitch, David H.; Blouet, Clemence (2021-07-13)
    The mediobasal hypothalamus (MBH; arcuate nucleus of the hypothalamus [ARH] and median eminence [ME]) is a key nutrient sensing site for the production of the complex homeostatic feedback responses required for the maintenance of energy balance. Here, ...
  • Kristiansen, Martin; Lindén, Christina; Qvarlander, Sara; Wåhlin, Anders; Ambarki, Khalid; Hallberg, Per; Eklund, Anders; Jóhannesson, Gauti (2020-11-19)
    Purpose: To examine feasibility of phase-contrast magnetic resonance imaging (PCMRI) and to assess blood flow rate in the ophthalmic artery (OA) in patients with normal tension glaucoma (NTG) compared with healthy controls. Methods: Sixteen patients ...
  • Tribble, James R.; Otmani, Amin; Sun, Shanshan; Ellis, Sevannah A.; Cimaglia, Gloria; Vohra, Rupali; Jöe, Melissa; Lardner, Emma; Venkataraman, Abinaya P.; Domínguez-Vicent, Alberto; Kokkali, Eirini; Rho, Seungsoo; Jóhannesson, Gauti; Burgess, Robert W.; Fuerst, Peter G.; Brautaset, Rune; Kolko, Miriam; Morgan, James E.; Crowston, Jonathan G.; Votruba, Marcela; Williams, Pete A. (2021-07)
    Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to ...
  • Su, Xiujuan; Yu, Yongfu; Meng, Lulu; Duan, Tony; Zhao, Yan; László, Krisztina D.; Valdimarsdóttir, Unnur Anna; Hua, Jing; Li, Jiong (2021-10-01)
    OBJECTIVE: This study aimed to examine the association of a mother's loss of a close relative before or during pregnancy with intellectual disability (ID) in the offspring. METHODS: We performed a nationwide population-based cohort study based on Danish ...
  • Thorsteinsson, Daniel A.; Stefánsdóttir, Vigdís Fjóla; Eysteinsson, Þór; Thorisdottir, Sigridur; Jónsson, Jón Jóhannes (2021-08)
    The study objective was to delineate the genetics of inherited retinal degenerations (IRDs) in Iceland, a small nation of 364.000 and a genetic isolate. Benefits include delineating novel pathogenic genetic variants and defining genetically homogenous ...
  • Levy, Marína Rós; Thors, Valtýr Stefánsson; Elínardóttir, Sigríður Haralds; Möller, Alma D.; Haraldsson, Ásgeir (2021-09-30)
    Background Global death rate in children has been declining during the last decades worldwide, especially in high income countries. This has been attributed to several factors, including improved prenatal and perinatal care, immunisations, infection ...
  • Stel, Vianda S.; de Jong, Rianne W.; Kramer, Anneke; Andrusev, Anton M.; Baltar, José M.; Barbullushi, Myftar; Bell, Samira; Castro de la Nuez, Pablo; Cernevskis, Harijs; Couchoud, Cécile; De Meester, Johan; Eriksen, Bjørn O.; Gârneaţă, Liliana; Golan, Eliezer; Helve, Jaakko; Hemmelder, Marc H.; Hommel, Kristine; Ioannou, Kyriakos; Jarraya, Faiçal; Kantaria, Nino; Kerschbaum, Julia; Komissarov, Kirill S.; Magaz, Ángela; Mercadal, Lucile; Ots-Rosenberg, Mai; Pálsson, Runólfur; Rahmel, Axel; Rydell, Helena; Savino, Manuela; Seyahi, Nurhan; Slon Roblero, Maria F.; Stojceva-Taneva, Olivera; van der Tol, Arjan; Vazelov, Evgueniy S.; Ziginskiene, Edita; Zurriaga, Óscar; Vanholder, Raymond C.; Massy, Ziad A.; Jager, Kitty J. (2021-07)
    The aims of this study were to determine the frequency of dialysis and kidney transplantation and to estimate the regularity of comprehensive conservative management (CCM) for patients with kidney failure in Europe. This study uses data from the ERA-EDTA ...
  • Runólfsdóttir, Hrafnhildur L.; Sayer, John A.; Indridason, Olafur S.; Eðvarðsson, Viðar Örn; Jensson, Brynjar O.; Arnadottir, Gudny A.; Gudjonsson, Sigurjon A.; Fridriksdottir, Run; Katrinardottir, Hildigunnur; Gudbjartsson, Daniel; Thorsteinsdottir, Unnur; Sulem, Patrick; Stefansson, Kari; Pálsson, Runólfur (2021-03-11)
    Adenine phosphoribosyltransferase deficiency is a rare, autosomal recessive disorder of purine metabolism that causes nephrolithiasis and progressive chronic kidney disease. The small number of reported cases indicates an extremely low prevalence, ...
  • the Benign Esophageal Perforation Collaborative Group (2020-07-17)
    BACKGROUND: Time of diagnosis (TOD) of benign esophageal perforation is regarded as an important risk factor for clinical outcome, although convincing evidence is lacking. The aim of this study is to assess whether time between onset of perforation and ...
  • Shen, Qing; Sjölander, Arvid; Sloan, Erica K.; Walker, Adam K.; Fall, Katja; Valdimarsdóttir, Unnur Anna; Sparén, Pär; Smedby, Karin E.; Fang, Fang (2022-01-17)
    Background: Cancer patients experience increased risk of death from accident and suicide. Cognitive impairment induced by cancer-related inflammation and stress-related psychiatric symptoms may be underlying mechanisms. We therefore studied the association ...
  • Kalkhoran, Siavash Beikoghli; Kararigas, Georgios (2022-02-01)
    Biological sex influences disease development and progression. The steroid hormone 17β-oestradiol (E2), along with its receptors, is expected to play a major role in the manifestation of sex differences. E2 exerts pleiotropic effects in a system-specific ...
  • Jóhannsdóttir, Ásta; Egilson, Snæfríður Þóra; Haraldsdóttir, Freyja (2022-01-15)
    When conceptualising health and wellbeing among disabled people, the experience of internalised ableism must be considered. In this article, we argue that internalised ableism is indeed a health and wellbeing issue that materialises in numerous complex ...
  • Lyne, Lauren; Åkerstedt, Torbjörn; Alfredsson, Lars; Lehtonen, Tiina; Sævarsdóttir, Sædís; Klareskog, Lars; Westerlind, Helga (2022-01-05)
    Objective Most studies of rheumatoid arthritis (RA) and sleep have focused on established RA. We here investigate sleep quality and sleep duration in patients with newly diagnosed RA and during 1-12 years after diagnosis. Methods Data were collected ...