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Fletta eftir efnisorði "Neurology (clinical)"

Fletta eftir efnisorði "Neurology (clinical)"

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    Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies 
    Tariot, Pierre N.; Riviere, Marie Emmanuelle; Salloway, Stephen; Burns, Jeffrey M.; Snædal, Jón G; Borowsky, Beth; Lopez, Cristina Lopez; Liu, Fonda; Rouzade-Dominguez, Marie Laure; Cazorla, Pilar; Mousseau, Marie Catherine; Arkuszewski, Michal; Ricart, Javier; Viglietta, Vissia; Sui, Yihan; Caputo, Angelika; Langbaum, Jessica B.; Reiman, Eric M.; Graf, Ana (2024-11)
    INTRODUCTION: The Alzheimer's Prevention Initiative (API) Generation Studies evaluated the BACE inhibitor umibecestat for Alzheimer's disease (AD) prevention. The studies were terminated early, and the reversibility of umibecestat's side effects was ...
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    Trans-ethnic genomic informed risk assessment for Alzheimer's disease : An International Hundred K+ Cohorts Consortium study 
    Sleiman, Patrick M.; Qu, Hui Qi; Connolly, John J.; Mentch, Frank; Pereira, Alexandre; Lotufo, Paulo A.; Tollman, Stephen; Choudhury, Ananyo; Ramsay, Michele; Kato, Norihiro; Ozaki, Kouichi; Mitsumori, Risa; Jeon, Jae Pil; Hong, Chang Hyung; Son, Sang Joon; Roh, Hyun Woong; Lee, Dong gi; Mukadam, Naaheed; Foote, Isabelle F.; Marshall, Charles R.; Butterworth, Adam; Prins, Bram P.; Glessner, Joseph T.; Hakonarson, Hakon (2023-12)
    BACKGROUND: As a collaboration model between the International HundredK+ Cohorts Consortium (IHCC) and the Davos Alzheimer's Collaborative (DAC), our aim was to develop a trans-ethnic genomic informed risk assessment (GIRA) algorithm for Alzheimer's ...