Browsing IRIS by Subject "Maedi-visna"

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Maedi-visna virus Vif protein uses motifs distinct from HIV-1 Vif to bind zinc and cofactor required for A3 degradation : Maedi-visna virus Vif interactions with cellular factors

Knecht, Kirsten M; Hu, Yingxia; Rubene, Diana; Cook, Matthew; Ziegler, Samantha J; Jónsson, Stefán Ragnar; Xiong, Yong (2021)

The mammalian apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3 (APOBEC3 or A3) family of cytidine deaminases restrict viral infections by mutating viral DNA and impeding reverse transcription. To overcome this antiviral activity, most ...

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