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Browsing IRIS by Author "Lund, Sigrún Helga"

Browsing IRIS by Author "Lund, Sigrún Helga"

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    Application of ChatGPT for automated problem reframing across academic domains 
    Einarsson, Hafsteinn; Lund, Sigrún Helga; Jónsdóttir, Anna Helga (2024-06)
    This paper explores the potential of large language models, specifically ChatGPT, to reframe problems from probability theory and statistics, making them accessible to students across diverse academic fields including biology, economics, law, and ...
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    Association of eGFR and mortality with use of a joint model : results of a nationwide study in Iceland 
    Jónsson, Arnar Jan; Lund, Sigrún Helga; Eriksen, Bjørn O; Pálsson, Runólfur; Indriðason, Ólafur Skúli (2023-09-29)
    OBJECTIVES: Prior studies on the association of estimated glomerular filtration rate (eGFR) and mortality have failed to include methods to account for repeated eGFR determinations. The aim of this study was to estimate the association between eGFR and ...
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    Can ultrasound on admission in active labor predict labor duration and a spontaneous delivery? 
    Hjartardóttir, Hulda; Lund, Sigrún Helga; Benediktsdóttir, Sigurlaug; Geirsson, Reynir T; Eggebø, Torbjørn M. (2021-04-23)
    Background: Identifying predictive factors for a normal outcome at admission in the labor ward would be of value for planning labor care, timing interventions, and preventing labor dystocia. Clinical assessments of fetal head station and position at ...
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    Comparison of medication adherence to different oral anticoagulants : population-based cohort study 
    Ingason, Arnar Bragi; Hreinsson, Jóhann P.; Lund, Sigrún Helga; Ágústsson, Arnar Snær; Rumba, Edward; Pálsson, Daníel; Reynisson, Indriði E.; Guðmundsdóttir, Brynja R; Önundarson, Páll Torfi; Björnsson, Einar Stefán (2023-01-01)
    OBJECTIVE: Previous observational studies have yielded conflicting results on whether medication adherence differs between patients receiving warfarin and direct oral anticoagulants (DOACs). Importantly, no study has adequately accounted for warfarin ...
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    Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor 
    Dowsett, Joseph; Ferkingstad, Egil; Rasmussen, Line Jee Hartmann; Thørner, Lise Wegner; Magnússon, Magnús Karl; Sugden, Karen; Þorleifsson, Guðmar; Frigge, Mike; Burgdorf, Kristoffer Sølvsten; Ostrowski, Sisse Rye; Sørensen, Erik; Erikstrup, Christian; Pedersen, Ole Birger; Hansen, Thomas Folkmann; Banasik, Karina; Brunak, Søren; Tragante, Vinicius; Lund, Sigrún Helga; Stefánsdóttir, Lilja; Gunnarson, Bjarni; Poulton, Richie; Arseneault, Louise; Caspi, Avshalom; Moffitt, Terrie E.; Gudbjartsson, Daníel Fannar; Eugen-Olsen, Jesper; Stefánsson, Hreinn; Stefánsson, Kári; Ullum, Henrik (2021-06-02)
    Soluble urokinase-type plasminogen activator receptor (suPAR) is a chronic inflammation marker associated with the development of a range of diseases, including cancer and cardiovascular disease. The genetics of suPAR remain unexplored but may shed ...
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    Faraldsfræði tveggja Laurén-flokka kirtilfrumukrabbameina í maga á Íslandi árin 1990-2009 
    Ólafsdóttir, Halla Sif; Alexíusdottir, Kristín; Jónasson, Jón Gunnlaugur; Lund, Sigrún Helga; Jónsson, Þorvaldur; Skuladottir, Halla (2016-03-02)
    Inngangur: Magakrabbamein var algengasta krabbameinið á Íslandi upp úr miðri 20. öld en er nú einungis 2-3% krabbameina. Markmið þessarar rannsóknar var að gera faraldsfræðilegan samanburð á tveimur meginflokkum kirtilfrumukrabbameina í maga samkvæmt ...
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    Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis 
    Magnússon, Magnús Ingvi; Agnarsson, Bjarni Agnar; Jónasson, Jón Gunnlaugur; Tryggvason, Þórður; Aeffner, Famke; le Roux, Louise; Magnusdottir, Droplaug N.; Gunnarsdóttir, Helga Sigrún; Alexíusdóttir, Kristín K.; Gunnarsdottir, Kristbjorg; Söebech, Emilia; Runarsdottir, Hjaltey; Jónsdóttir, Erna María; Kristinsdóttir, Bjarney Sif; Olafsson, Sigurgeir; Knutsdottir, Hildur; Þorsteinsdóttir, Unnur; Úlfarsson, Magnús Örn; Guðbjartsson, Daníel Fannar; Saemundsdottir, Jona; Magnusson, Olafur T.; Norddahl, Gudmundur L.; Watson, J. E.Vivienne; Rafnar, Thorunn; Lund, Sigrún Helga; Stefánsson, Kári (2023-10-19)
    Background: The TNM system is used to assess prognosis after colorectal cancer (CRC) diagnosis. Other prognostic factors reported include histopathological assessments of the tumour, tumour mutations and proteins in the blood. As some of these factors ...
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    Incidence of and risk factors of chronic kidney disease: results of a nationwide study in Iceland 
    Jónsson, Arnar Jan; Lund, Sigrún Helga; Eriksen, Bjorn O.; Pálsson, Runólfur; Indriðason, Ólafur Skúli (2022-07-01)
    Background: Information on the incidence of chronic kidney disease (CKD) in the general population is scarce. This study examined the incidence and risk factors of CKD stages 1-5 in Iceland, based on multiple markers of kidney damage. Methods: All serum ...
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    Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effect 
    Styrkársdóttir, Unnur; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Andri Stefánsson, Ólafur; Sævarsdóttir, Sædís; Lund, Sigrún Helga; Rafnar, Thorunn; Hoshijima, Kazuyuki; Novak, Kendra; Oreiro, Natividad; Rego-Perez, Ignacio; Hansen, Channing; Kazmers, Nikolas; Kiemeney, Lambertus A; Blanco, Francisco J; Barker, Tyler; Kloppenburg, Margreet; Jurynec, Michael J; Gudbjartsson, Daniel F; Jónsson, Helgi; Þorsteinsdóttir, Unnur; Stefánsson, Kári (2023-06)
    OBJECTIVES: Erosive hand osteoarthritis (EHOA) is a severe subset of hand osteoarthritis (OA). It is unclear if EHOA is genetically different from other forms of OA. Sequence variants at ten loci have been associated with hand OA but none with EHOA. ...
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    Pituitary dysfunction following mild traumatic brain injury in female athletes 
    Claessen, Lára Ósk Eggertsdóttir; Kristjánsdóttir, Hafrún; Jónsdóttir, María Kristín; Lund, Sigrún Helga; Kristensen, Ingunn Unnsteinsdóttir; Sigurjónsdóttir, Helga Ágústa (2024-02)
    Objective: Pituitary dysfunction following mild traumatic brain injury can have serious physical and psychological consequences, making correct diagnosis and treatment essential. To the best of our knowledge, this study is the first to study the ...
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    Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura 
    Bjornsdottir, Gyda; Chalmer, Mona A.; Stefánsdóttir, Lilja; Skuladottir, Astros Th; Einarsson, Gudmundur; Andrésdóttir, Margrét; Beyter, Doruk; Ferkingstad, Egil; Gretarsdottir, Solveig; Halldórsson, Bjarni Vilhjálmur; Halldórsson, Gísli Hreinn; Helgadottir, Anna; Helgason, Hannes; Hjorleifsson Eldjarn, Grimur; Jonasdottir, Adalbjorg; Jonasdottir, Aslaug; Jónsdóttir, Ingileif; Knowlton, Kirk U.; Nadauld, Lincoln D.; Lund, Sigrún Helga; Magnusson, Olafur Th; Melsted, Páll; Moore, Kristjan H.S.; Oddsson, Asmundur; Olason, Pall I.; Sigurdsson, Asgeir; Stefansson, Olafur A.; Saemundsdottir, Jona; Sveinbjornsson, Gardar; Tragante, Vinicius; Unnsteinsdottir, Unnur; Walters, Guðmundur Bragi; Zink, Florian; Rødevand, Linn; Andreassen, Ole A.; Igland, Jannicke; Lie, Rolv T.; Haavik, Jan; Banasik, Karina; Brunak, Søren; Didriksen, Maria; T. Bruun, Mie; Erikstrup, Christian; Kogelman, Lisette J.A.; Nielsen, Kaspar R.; Sørensen, Erik; Pedersen, Ole B.; Ullum, Henrik; Bay, Jakob; Boldsen, Jens K.; Brodersen, Thorsten; Burgdorf, Kristoffer; Dinh, Khoa M.; Dowsett, Joseph; Feenstra, Bjarke; Geller, Frank; Hindhede, Lotte; Hjalgrim, Henrik; Jacobsen, Rikke L.; Jemec, Gregor; Kaspersen, Katrine; Kjerulf, Bertram D.; Larsen, Margit A.H.; Louloudis, Ioannis; Lundgaard, Agnete; Mikkelsen, Susan; Mikkelsen, Christina; Nissen, Ioanna; Nyegaard, Mette; Henriksen, Alexander P.; Rohde, Palle D.; Rostgaard, Klaus; Swinn, Michael; Thørner, Lise W.; Bruun, Mie T.; Werge, Thomas; Westergaard, David; Masson, Gisli; Þorsteinsdóttir, Unnur; Olesen, Jes; Ludvigsson, Petur; Thorarensen, Ólafur; Bjornsdottir, Anna; Sigurdardottir, Gudrun R.; Sveinsson, Ólafur Árni; Ostrowski, Sisse R.; Holm, Hilma; Gudbjartsson, Daniel F.; Thorleifsson, Gudmar; Sulem, Patrick; Stefansson, Hreinn; Thorgeirsson, Thorgeir E.; Hansen, Thomas F.; Stefánsson, Kári (2023-11)
    Migraine is a complex neurovascular disease with a range of severity and symptoms, yet mostly studied as one phenotype in genome-wide association studies (GWAS). Here we combine large GWAS datasets from six European populations to study the main migraine ...