Browsing by Subject "therapeutics"

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Inhibition of KDM1A activity restores adult neurogenesis and improves hippocampal memory in a mouse model of Kabuki syndrome

Zhang, Li; Pilarowski, Genay; Pich, Emilio Merlo; Nakatani, Atsushi; Dunlop, John; Baba, Rina; Matsuda, Satoru; Daini, Masaki; Hattori, Yasushi; Matsumoto, Shigemitsu; Ito, Mitsuhiro; Kimura, Haruhide; Björnsson, Hans Tómas (2021-03-12)

Kabuki syndrome (KS) is a rare cause of intellectual disability primarily caused by loss-of-function mutations in lysine-specific methyltransferase 2D ( KMT2D), which normally adds methyl marks to lysine 4 on histone 3. Previous studies have shown that ...
Therapeutics and COVID-19-A living WHO guideline : Endorsement by the Scandinavian Society of Anaesthesiology and Intensive Care Medicine

Møller, Morten H; Chew, Michelle S; Olkkola, Klaus T; Rehn, Marius; Yli-Hankala, Arvi; Sigurðsson, Martin Ingi (2022-02-28)

The Clinical Practice Committee of the Scandinavian Society of Anaesthesiology and Intensive Care Medicine endorses the Living WHO guideline on therapeutics and COVID-19. This trustworthy continuously updated guideline serves as a highly useful decision ...

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