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Fletta eftir efnisorði "Quantitative trait"

Fletta eftir efnisorði "Quantitative trait"

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    Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor 
    Dowsett, Joseph; Ferkingstad, Egil; Rasmussen, Line Jee Hartmann; Thørner, Lise Wegner; Magnússon, Magnús Karl; Sugden, Karen; Þorleifsson, Guðmar; Frigge, Mike; Burgdorf, Kristoffer Sølvsten; Ostrowski, Sisse Rye; Sørensen, Erik; Erikstrup, Christian; Pedersen, Ole Birger; Hansen, Thomas Folkmann; Banasik, Karina; Brunak, Søren; Tragante, Vinicius; Lund, Sigrún Helga; Stefánsdóttir, Lilja; Gunnarson, Bjarni; Poulton, Richie; Arseneault, Louise; Caspi, Avshalom; Moffitt, Terrie E.; Gudbjartsson, Daníel Fannar; Eugen-Olsen, Jesper; Stefánsson, Hreinn; Stefánsson, Kári; Ullum, Henrik (2021-06-02)
    Soluble urokinase-type plasminogen activator receptor (suPAR) is a chronic inflammation marker associated with the development of a range of diseases, including cancer and cardiovascular disease. The genetics of suPAR remain unexplored but may shed ...
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    Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits 
    van Setten, Jessica; Verweij, Niek; Mbarek, Hamdi; Niemeijer, Maartje N.; Trompet, Stella; Arking, Dan E.; Brody, Jennifer A.; Gandin, Ilaria; Grarup, Niels; Hall, Leanne M.; Hemerich, Daiane; Lyytikäinen, Leo-Pekka; Mei, Hao; Müller-Nurasyid, Martina; Prins, Bram P.; Robino, Antonietta; Smith, Albert Vernon; Warren, Helen R.; Asselbergs, Folkert W.; Boomsma, Dorret I.; Caulfield, Mark J.; Eijgelsheim, Mark; Ford, Ian; Hansen, Torben; Harris, Tamara B.; Heckbert, Susan R.; Hottenga, Jouke-Jan; Iorio, Annamaria; Kors, Jan A.; Linneberg, Allan; MacFarlane, Peter W.; Meitinger, Thomas; Nelson, Christopher P.; Raitakari, Olli T.; Silva Aldana, Claudia T.; Sinagra, Gianfranco; Sinner, Moritz; Soliman, Elsayed Z.; Stoll, Monika; Uitterlinden, Andre; van Duijn, Cornelia M.; Waldenberger, Melanie; Alonso, Alvaro; Gasparini, Paolo; Gudnason, Vilmundur; Jamshidi, Yalda; Kääb, Stefan; Kanters, Jørgen K.; Lehtimäki, Terho; Munroe, Patricia B.; Peters, Annette; Samani, Nilesh J.; Sotoodehnia, Nona; Ulivi, Sheila; Wilson, James G.; de Geus, Eco J. C.; Jukema, J. Wouter; Stricker, Bruno; van der Harst, Pim; de Bakker, Paul I. W.; Isaacs, Aaron (Springer Science and Business Media LLC, 2019-01-24)
    Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR interval). In the current study, ...
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    Sequence variants with large effects on cardiac electrophysiology and disease 
    Norland, Kristján; Sveinbjornsson, Gardar; Thorolfsdottir, Rosa B; Davidsson, Olafur B.; Tragante, Vinicius; Rajamani, Sridharan; Helgadottir, Anna; Grétarsdóttir, Sólveig; van Setten, Jessica; Asselbergs, Folkert W.; Sverrisson, Jon Th.; Stephensen, Sigurdur Sverrir; Óskarsson, Gylfi; Sigurðsson, Emil Lárus; Andersen, Karl; Danielsen, Ragnar; Thorgeirsson, Gudmundur; Thorsteinsdottir, Unnur; Arnar, Davíð O.; sulem, patrick; Holm, Hilma; Gudbjartsson, Daniel; Stefansson, Kari (Springer Science and Business Media LLC, 2019-10-22)
    Features of the QRS complex of the electrocardiogram, reflecting ventricular depolarisation, associate with various physiologic functions and several pathologic conditions. We test 32.5 million variants for association with ten measures of the QRS ...
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    Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function 
    Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David; Hagenaars, Saskia P.; Ritchie, Stuart J.; Marioni, Riccardo E.; Fawns-Ritchie, Chloe; Liewald, David C. M.; Okely, Judith A.; Ahola-Olli, Ari V.; Barnes, Catriona L. K.; Bertram, Lars; Bis, Joshua C.; Burdick, Katherine E.; Christoforou, Andrea; DeRosse, Pamela; Djurovic, Srdjan; Espeseth, Thomas; Giakoumaki, Stella; Giddaluru, Sudheer; Gustavson, Daniel E.; Hayward, Caroline; Hofer, Edith; Ikram, M. Arfan; Karlsson, Robert; Knowles, Emma; Lahti, Jari; Leber, Markus; Li, Shuo; Mather, Karen A.; Melle, Ingrid; Morris, Derek; Oldmeadow, Christopher; Palviainen, Teemu; Payton, Antony; Pazoki, Raha; Petrovic, Katja; Reynolds, Chandra A.; Sargurupremraj, Muralidharan; Scholz, Markus; Smith, Jennifer A.; Smith, Albert Vernon; Terzikhan, Natalie; Thalamuthu, Anbupalam; Trompet, Stella; van der Lee, Sven J.; Ware, Erin B.; Windham, B. Gwen; Wright, Margaret J.; Yang, Jingyun; Yu, Jin; Ames, David; Amin, Najaf; Amouyel, Philippe; Andreassen, Ole A.; Armstrong, Nicola J.; Assareh, Amelia A.; Attia, John R.; Attix, Deborah; Avramopoulos, Dimitrios; Bennett, David A.; Böhmer, Anne C.; Boyle, Patricia A.; Brodaty, Henry; Campbell, Harry; Cannon, Tyrone D.; Cirulli, Elizabeth T.; Congdon, Eliza; Conley, Emily Drabant; Corley, Janie; Cox, Simon R.; Dale, Anders M.; Dehghan, Abbas; Dick, Danielle; Dickinson, Dwight; Eriksson, Johan G.; Evangelou, Evangelos; Faul, Jessica D.; Ford, Ian; Freimer, Nelson A.; Gao, He; Giegling, Ina; Gillespie, Nathan A.; Gordon, Scott D.; Gottesman, Rebecca F.; Griswold, Michael E.; Gudnason, Vilmundur; Harris, Tamara B.; Hartmann, Annette M.; Hatzimanolis, Alex; Heiss, Gerardo; Holliday, Elizabeth G.; Joshi, Peter K.; Kähönen, Mika; Kardia, Sharon L. R.; Karlsson, Ida; Kleineidam, Luca; Knopman, David S.; Kochan, Nicole A.; Konte, Bettina; Kwok, John B.; Le Hellard, Stephanie; Lee, Teresa; Lehtimäki, Terho; Li, Shu-Chen; Lill, Christina M.; Liu, Tian; Koini, Marisa; London, Edythe; Longstreth, Will T.; Lopez, Oscar L.; Loukola, Anu; Luck, Tobias; Lundervold, Astri J.; Lundquist, Anders; Lyytikäinen, Leo-Pekka; Martin, Nicholas G.; Montgomery, Grant W.; Murray, Alison D.; Need, Anna C.; Noordam, Raymond; Nyberg, Lars; Ollier, William; Papenberg, Goran; Pattie, Alison; Polasek, Ozren; Poldrack, Russell A.; Psaty, Bruce M.; Reppermund, Simone; Riedel-Heller, Steffi G.; Rose, Richard J.; Rotter, Jerome I.; Roussos, Panos; Rovio, Suvi P.; Saba, Yasaman; Sabb, Fred W.; Sachdev, Perminder S.; Satizabal, Claudia L.; Schmid, Matthias; Scott, Rodney J.; Scult, Matthew A.; Simino, Jeannette; Slagboom, P. Eline; Smyrnis, Nikolaos; Soumaré, Aïcha; Stefanis, Nikos C.; Stott, David J.; Straub, Richard E.; Sundet, Kjetil; Taylor, Adele M.; Taylor, Kent D.; Tzoulaki, Ioanna; Tzourio, Christophe; Uitterlinden, André; Vitart, Veronique; Voineskos, Aristotle N.; Kaprio, Jaakko; Wagner, Michael; Wagner, Holger; Weinhold, Leonie; Wen, K. Hoyan; Widen, Elisabeth; Yang, Qiong; Zhao, Wei; Adams, Hieab H. H.; Arking, Dan E.; Bilder, Robert M.; Bitsios, Panos; Boerwinkle, Eric; Chiba-Falek, Ornit; Corvin, Aiden; De Jager, Philip L.; Debette, Stéphanie; Donohoe, Gary; Elliott, Paul; Fitzpatrick, Annette L.; Gill, Michael; Glahn, David C.; Hägg, Sara; Hansell, Narelle K.; Hariri, Ahmad R.; Ikram, M. Kamran; Jukema, J. Wouter; Vuoksimaa, Eero; Keller, Matthew C.; Kremen, William S.; Launer, Lenore; Lindenberger, Ulman; Palotie, Aarno; Pedersen, Nancy L.; Pendleton, Neil; Porteous, David J.; Räikkönen, Katri; Raitakari, Olli T.; Ramirez, Alfredo; Reinvang, Ivar; Rudan, Igor (Springer Science and Business Media LLC, 2018-05-29)
    General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16–102) ...