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Browsing by Subject "Models, Biological"

Browsing by Subject "Models, Biological"

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    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer 
    Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
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    Spermatogonia loss correlates with LAMA 1 expression in human prepubertal testes stored for fertility preservation 
    Kurek, Magdalena; Åkesson, Elisabet; Yoshihara, Masahito; Oliver, Elizabeth; Cui, Yanhua; Becker, Martin; Alves-Lopes, João Pedro; Bjarnason, Ragnar Grímur; Romerius, Patrik; Sundin, Mikael; Nyström, Ulrika Norén; Langenskiöld, Cecilia; Vogt, Hartmut; Henningsohn, Lars; Petersen, Cecilia; Söder, Olle; Guo, Jingtao; Mitchell, Rod T.; Jahnukainen, Kirsi; Stukenborg, Jan Bernd (2021-01-27)
    Fertility preservation for male childhood cancer survivors not yet capable of producing ma-ture spermatozoa, relies on experimental approaches such as testicular explant culture. Although the first steps in somatic maturation can be observed in human ...
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    Symmetry breaking and effects of nutrient walkway in time-dependent bone remodeling incorporating poroelasticity 
    Esposito, L; Minutolo, V; Gargiulo, P; Fraldi, M (2022-04-08)
    Bone is an extraordinary biological material that continuously adapts its hierarchical microstructure to respond to static and dynamic loads for offering optimal mechanical features, in terms of stiffness and toughness, across different scales, from ...