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Browsing by Subject "Methotrexate"

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Comorbidities and chance of remission in patients with early rheumatoid arthritis receiving methotrexate as first-line therapy : a Swedish observational nationwide study

Tidblad, Liselotte; Westerlind, Helga; Delcoigne, Bénédicte; Askling, Johan; Saevarsdottir, Saedis (2023-12-20)

OBJECTIVES: This study aims to examine whether comorbidities affect the likelihood of reaching primary remission on methotrexate monotherapy as the first disease-modifying antirheumatic drug (DMARD) in early rheumatoid arthritis (RA). METHODS: We used ...
Does autoimmune thyroid disease affects rheumatoid arthritis disease activity or response to methotrexate?

Waldenlind, Kristin; Delcoigne, Bénédicte; Saevarsdottir, Saedis; Askling, Johan (BMJ, 2020-07-15)

Objective: To investigate if autoimmune thyroid disease (AITD) impacts rheumatoid arthritis (RA) disease activity or response to methotrexate. Methods A nationwide register-based cohort study of 9 004 patients with new-onset RA from the Swedish ...
Does persistence to methotrexate treatment in early rheumatoid arthritis have a familial component?

Sysojev, Anton Öberg; Frisell, Thomas; Delcoigne, Bénédicte; Saevarsdottir, Saedis; Askling, Johan; Westerlind, Helga (2022-08-06)

Objectives: To assess whether persistence to treatment with methotrexate (MTX) in early rheumatoid arthritis (RA) is shared among first-degree relatives with RA and to estimate any underlying heritability. Methods: First-degree relative pairs diagnosed ...
Thiopurine Enhanced ALL Maintenance (TEAM) : study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0–45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol

Toksvang, Linea Natalie; Als-Nielsen, Bodil; Bacon, Christopher; Bertasiute, Ruta; Duarte, Ximo; Escherich, Gabriele; Helgadóttir, Elín Anna; Johannsdottir, Inga Rinvoll; Jónsson, Ólafur Gísli; Kozlowski, Piotr; Langenskjöld, Cecilia; Lepik, Kristi; Niinimäki, Riitta; Overgaard, Ulrik Malthe; Punab, Mari; Räty, Riikka; Segers, Heidi; van der Sluis, Inge; Smith, Owen Patrick; Strullu, Marion; Vaitkevičienė, Goda; Wik, Hilde Skuterud; Heyman, Mats; Schmiegelow, Kjeld (2022-05-02)

Background: A critical challenge in current acute lymphoblastic leukemia (ALL) therapy is treatment intensification in order to reduce the relapse rate in the subset of patients at the highest risk of relapse. The year-long maintenance phase is essential ...

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Browsing by Subject "Methotrexate"

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