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Browsing by Subject "Immunology and Allergy"

Browsing by Subject "Immunology and Allergy"

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  • Novotny, Ella N.; White, Samuel J.; Wilson, A. Douglas; Stefánsdóttir, Sara Björk; Tijhaar, Edwin; Jónsdóttir, Sigríður; Frey, Rebekka; Reiche, Dania; Rose, Horst; Rhyner, Claudio; Schüpbach-Regula, Gertraud; Þorsteinsdóttir, Sigurbjörg; Alcocer, Marcos; Marti, Eliane (2021-04)
    Background: Allergy to bites of blood-sucking insects, including biting midges, can affect both human and veterinary patients. Horses are often suffering from an IgE-mediated allergic dermatitis caused by bites of midges (Culicoides spp). With the aim ...
  • Grönwall, Caroline; Liljefors, Lisa; Bang, Holger; Hensvold, Aase H.; Hansson, Monika; Mathsson-Alm, Linda; Israelsson, Lena; Joshua, Vijay; Svärd, Anna; Stålesen, Ragnhild; Titcombe, Philip J.; Steen, Johanna; Piccoli, Luca; Sherina, Natalia; Clavel, Cyril; Svenungsson, Elisabet; Gunnarsson, Iva; Sævarsdóttir, Sædís; Kastbom, Alf; Serre, Guy; Alfredsson, Lars; Malmström, Vivianne; Rönnelid, Johan; Catrina, Anca I.; Lundberg, Karin; Klareskog, Lars (2021-05-20)
    Seropositive rheumatoid arthritis (RA) is characterized by the presence of rheumatoid factor (RF) and anti-citrullinated protein autoantibodies (ACPA) with different fine-specificities. Yet, other serum anti-modified protein autoantibodies (AMPA), e.g. ...
  • Brynjólfsson, Siggeir Fannar; Sigurgrímsdóttir, Hildur; Einarsdóttir, Elín D.; Björnsdóttir, Guðrún Ása; Ármannsdóttir, Brynja; Baldvinsdóttir, Guðrún E.; Bjarnason, Agnar; Guðlaugsson, Ólafur; Guðmundsson, Sveinn Viðar; Sigurðardóttir, Sigurveig T.; Löve, Arthur; Kristinsson, Karl Gústaf; Lúðvíksson, Björn Rúnar (2021-06-10)
    A detailed understanding of the antibody response against SARS-CoV-2 is of high importance, especially with the emergence of novel vaccines. A multiplex-based assay, analyzing IgG, IgM, and IgA antibodies against the receptor binding domain (RBD), spike ...
  • Haugen, Ida K.; Felson, David; Abhishek, Abhishek; Berenbaum, Francis; Edwards, John James; Herrero Beaumont, Gabriel; Hermann-Eriksen, Merete; Hill, Catherine L.; Ishimori, Mariko; Jonsson, Helgi; Karjalainen, Teemu; Leung, Ying Ying; Maheu, Emmanuel; Mallen, Christian D.; Moe, Rikke Helene; Ramonda, Roberta; Ritschl, Valentin; Stamm, Tanja A.; Szekanecz, Zoltan; van der Giesen, Florus J.; Ritt, Marco J.P.F.; Wittoek, Ruth; Kjeken, Ingvild; Osteras, Nina; van de Stadt, Lotte A.; Englund, Martin; Dziedzic, Krysia S.; Marshall, M.; Bierma-Zeinstra, Sita; Hansen, Paul; Greibrokk, Elsie; Smeets, Wilma; Kloppenburg, Margreet (2022-02-04)
    ObjectivesIn Phase 1 of developing new hand osteoarthritis (OA) classification criteria, features associated with hand OA were identified in a population with hand complaints. Radiographic findings could better discriminate patients with hand OA and ...
  • Jensen, Kirstine Nolling; Heijink, Marieke; Giera, Martin; Freysdottir, Jona; Hardardottir, Ingibjorg (2022-01-14)
    Purpose: To determine the effects of dietary omega-3 polyunsaturated fatty acids (PUFAs) on recruitment of natural killer (NK) cells and resolution responses in antigen-induced peritonitis in mice. Methods: Mice were fed fish oil-enriched or control ...
  • Lindström, Ulf; Di Giuseppe, Daniela; Delcoigne, Bénédicte; Glintborg, Bente; Möller, Burkhard; Ciurea, Adrian; Pombo-Suarez, Manuel; Sanchez-Piedra, Carlos; Eklund, Kari; Relas, Heikki; Guðbjörnsson, Björn; Löve, Þorvarður Jón; Jones, Gareth T.; Codreanu, Catalin; Ionescu, Ruxandra; Nekvindova, Lucie; Závada, Jakub; Atas, Nuh; Yolbas, Servet; Fagerli, Karen Minde; Michelsen, Brigitte; Rotar, Ziga; Tomšič, Matija; Iannone, Florenzo; Santos, Maria Jose; Avila-Ribeiro, Pedro; Ørnbjerg, Lykke Midtbøll; Østergaard, Mikkel; Jacobsson, Lennart T.H.; Askling, Johan; Nissen, Michael J. (2021-06-03)
    Background Comedication with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) during treatment with tumour necrosis factor inhibitors (TNFi) is extensively used in psoriatic arthritis (PsA), although the additive benefit remains ...
  • Aradottir, Sigridur Sunna; Kristoffersson, Ann Charlotte; Roumenina, Lubka T.; Bjerre, Anna; Kashioulis, Pavlos; Pálsson, Runólfur; Karpman, Diana (2021-06-10)
    Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS ...
  • Harrison, Stephanie C.; Tsilifis, Christo; Slatter, Mary A.; Nademi, Zohreh; Worth, Austen; Veys, Paul; Ponsford, Mark J.; Jolles, Stephen; Al-Herz, Waleed; Flood, Terence; Cant, Andrew J.; Doffinger, Rainer; Barcenas-Morales, Gabriela; Carpenter, Ben; Hough, Rachael; Haraldsson, Ásgeir; Heimall, Jennifer; Grimbacher, Bodo; Abinun, Mario; Gennery, Andrew R. (2021-02-01)
    Autosomal dominant hyper-IgE syndrome caused by dominant-negative loss-of-function mutations in signal transducer and activator of transcription factor 3 (STAT3) (STAT3-HIES) is a rare primary immunodeficiency with multisystem pathology. The quality ...
  • Westerlind, Helga; Palmqvist, Ida; Saevarsdottir, Saedis; Alfredsson, Lars; Klareskog, Lars; Di Giuseppe, Daniela (2021-08-07)
    BACKGROUND: Tea is a popular beverage around the world and has properties that can affect the immune system. The association between tea consumption and the risk of rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, ...
  • Framme, Jenny Lingman; Lundqvist, Christina; Lundell, Anna Carin; van Schouwenburg, Pauline A.; Lemarquis, Andri L.; Thörn, Karolina; Lindgren, Susanne; Gudmundsdottir, Judith; Lundberg, Vanja; Degerman, Sofie; Zetterström, Rolf H.; Borte, Stephan; Hammarström, Lennart; Telemo, Esbjörn; Hultdin, Magnus; van der Burg, Mirjam; Fasth, Anders; Oskarsdóttir, Sólveig; Ekwall, Olov (2022-01)
    Background: Population-based neonatal screening using T-cell receptor excision circles (TRECs) identifies infants with profound T lymphopenia, as seen in cases of severe combined immunodeficiency, and in a subgroup of infants with 22q11 deletion syndrome ...
  • Olafsson, Sigurdur; Rögnvaldsson, Sigurjon; Bergmann, Ottar M.; Jonasson, Jon G.; Benitez Hernandez, Ubaldo; Björnsson, Einar S. (2021-06)
    Background & Aims: The incidence of cirrhosis in Iceland has been the lowest in the world with only 3 cases per 100,000 inhabitants. Alcohol consumption has almost doubled in Iceland from 1980 to 2016. Obesity has also risen and hepatitis C virus has ...
  • Stockfelt, Marit; Lundell, Anna Carin; Hetland, Merete Lund; Østergaard, Mikkel; Uhlig, Till; Heiberg, Marte Schrumpf; Haavardsholm, Espen A.; Nurmohamed, Michael T.; Lampa, Jon; Nordström, Dan; Petersen, Kim Hørslev; Guðbjörnsson, Björn; Gröndal, Gerður; Aldridge, Jonathan; Andersson, Kerstin; Blennow, Kaj; Zetterberg, Henrik; van Vollenhoven, Ronald; Rudin, Anna (2021-07-13)
    Background: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics ...
  • Árnason, Níels Árni; Johannsson, Freyr; Landrö, Ragna; Harðarsson, Björn; Guðmundsson, Sveinn; Lian, Aina Mari; Reseland, Janne; Rolfsson, Ottar; Sigurjónsson, Ólafur Eysteinn (2022-03)
    Platelet granules contain a diverse group of proteins. Upon activation and during storage, platelets release a number of proteins into the circulation or supernatant of stored platelet concentrate (PC). The aim of this work was to investigate the effect ...
  • Morris, Cindy E.; Carrera, Natalia Ramirez; Berge, Odile; Lacroix, Christelle; Monteil, Cécile; Chandeysson, Charlotte; Guilbaud, Caroline; Blischke, Anett; Sigurbjörnsdóttir, Margrét Auður; Vilhelmsson, Oddur Þór (2022-03)
    Here we report, for the first time, the occurrence of the bacteria from the species complex Pseudomonas syringae in Iceland. We isolated this bacterium from 35 of the 38 samples of angiosperms, moss, ferns and leaf litter collected across the island ...
  • Lyne, Lauren; Åkerstedt, Torbjörn; Alfredsson, Lars; Lehtonen, Tiina; Sævarsdóttir, Sædís; Klareskog, Lars; Westerlind, Helga (2022-01-05)
    Objective Most studies of rheumatoid arthritis (RA) and sleep have focused on established RA. We here investigate sleep quality and sleep duration in patients with newly diagnosed RA and during 1-12 years after diagnosis. Methods Data were collected ...
  • Hedenstierna, L.; Opava, C. H.; Askling, J.; Jiang, X.; Ernestam, S.; Alfredsson, L.; Klareskog, L.; Sævarsdóttir, Sædís (2021-01-12)
    Objectives: To investigate whether low social support or low decision latitude at work correlate with risk of rheumatoid arthritis (RA), and whether and how those factors are associated with known modifiable risk factors for RA. Method: The Swedish ...
  • Curtis, Jeffrey R.; Weinblatt, Michael E.; Shadick, Nancy A.; Brahe, Cecilie H.; Østergaard, Mikkel; Hetland, Merete Lund; Sævarsdóttir, Sædís; Horton, Megan; Mabey, Brent; Flake, Darl D.; Ben-Shachar, Rotem; Sasso, Eric H.; Huizinga, T. W. (2021-01-04)
    BACKGROUND: The multi-biomarker disease activity (MBDA) test measures 12 serum protein biomarkers to quantify disease activity in RA patients. A newer version of the MBDA score, adjusted for age, sex, and adiposity, has been validated in two cohorts ...