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Fletta eftir efnisorði "Genome association"

Fletta eftir efnisorði "Genome association"

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    A proteome-wide genetic investigation identifies several sars-cov-2-exploited host targets of clinical relevance 
    Karim, Mohd A.; Shilts, Jarrod; Schwartzentruber, Jeremy; Hayhurst, James; Buniello, Annalisa; Mohammed, Elmutaz Shaikho Elhaj; Zheng, Jie; Holmes, Michael V.; Ochoa, David; Carmona, Miguel; Maranville, Joseph; Gaunt, Tom R.; Emilsson, Valur; Guðnason, Vilmundur G.; McDonagh, Ellen M.; Wright, Gavin J.; Ghoussaini, Maya; Dunham, Ian (2021-08-17)
    Background: The virus SARS-CoV-2 can exploit biological vulnerabilities (e.g. host proteins) in susceptible hosts that predispose to the development of severe COVID-19. Methods: To identify host proteins that may contribute to the risk of severe COVID-19, ...
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    Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits 
    Rafnar, Thorunn; Bjarni Gunnarsson; Ólafur A. Stefánsson; sulem, patrick; Ingason, Andrés; Frigge, Michael L.; Lilja Stefánsdóttir; Jón K. Sigurðsson; Tragante, Vinicius; Steinthorsdottir, Valgerdur; Styrkarsdottir, Unnur; Stacey, Simon N.; Gudmundsson, Julius; Arnadottir, Gudny; Oddsson, Asmundur; Zink, Florian; Halldorsson, Gisli; Sveinbjornsson, Gardar; Kristjansson, Ragnar; Ólafur B. Davíðsson; Anna Þórhildur Salvarsdóttir; Ásgeir Thoroddsen; Elísabet A. Helgadottir; Katrín Kristjánsdóttir; Orri Ingþórsson; Valur Guðmundsson; Geirsson, Reynir T.; Ragnheiður Árnadottir; Gudbjartsson, Daniel; Másson, Gísli; Asselbergs, Folkert W.; Jón Gunnlaugur Jónasson; Karl Ólafsson; Thorsteinsdottir, Unnur; Halldórsson, Bjarni; Thorleifsson, Gudmar; Stefansson, Kari (Springer Science and Business Media LLC, 2018-09-07)
    Uterine leiomyomas are common benign tumors of the myometrium. We performed a meta-analysis of two genome-wide association studies of leiomyoma in European women (16,595 cases and 523,330 controls), uncovering 21 variants at 16 loci that associate with ...