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Fletta eftir efnisorði "Gene Expression"

Fletta eftir efnisorði "Gene Expression"

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    NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients 
    March, Michael E.; Gutierrez-Uzquiza, Alvaro; Snorradottir, Asbjorg Osk; Matsuoka, Leticia S.; Balvis, Noelia Fonseca; Gestsson, Thorgeir; Nguyen, Kenny; Sleiman, Patrick M.A.; Kao, Charlly; Ísaksson, Helgi Jóhannes; Bragason, Birkir Thor; Ólafsson, Elías; Palsdottir, Astridur; Hakonarson, Hakon (2021-03-23)
    Hereditary cystatin C amyloid angiopathy is a dominantly inherited disease caused by a leucine to glutamine variant of human cystatin C (hCC). L68Q-hCC forms amyloid deposits in brain arteries associated with micro-infarcts, leading ultimately to ...
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    TREM-1+ Macrophages Define a Pathogenic Cell Subset in the Intestine of Crohn's Disease Patients 
    Caër, Charles; Gorreja, Frida; Forsskåhl, Sophia K.; Brynjólfsson, Siggeir Fannar; Szeponik, Louis; Magnusson, Maria K.; Börjesson, Lars G.; Block, Mattias; Bexe-Lindskog, Elinor; Wick, Mary Jo (2021-02-04)
    BACKGROUND AND AIMS: Uncontrolled activation of intestinal mononuclear phagocytes [MNPs] drives chronic inflammation in inflammatory bowel disease [IBD]. Triggering receptor expressed on myeloid cells 1 [TREM-1] has been implicated in the pathogenesis ...