Opin vísindi

Browsing by Subject "Blóðsjúkdómar"

Browsing by Subject "Blóðsjúkdómar"

Sort by: Order: Results:

  • Icon
    Health-related quality of life in ANCA-associated vasculitis and item generation for a disease-specific patient-reported outcome measure 
    Robson, Joanna C; Dawson, Jill; Cronholm, Peter F; Milman, Nataliya; Kellom, Katherine; Ashdown, Susan; Easley, Ebony; Farrar, John T.; Gebhart, Don; Lanier, Georgia; McAlear, Carol A; Peck, Jacqueline; Luqmani, Raashid A; Shea, Judy A; Tómasson, Gunnar; Merkel, Peter A (Dove Medical Press Ltd., 2018-01)
    Objective: The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are multisystem diseases of the small blood vessels. Patients experience irreversible damage and psychological effects from AAV and its treatment. An international ...
  • Icon
    Neutropenia and agranulocytosis during treatment of schizophrenia with clozapine versus other antipsychotics: an observational study in Iceland 
    Ingimarsson, Oddur; MacCabe, James; Haraldsson, Magnús; Jónsdóttir, Halldóra; Sigurdsson, Engilbert (Springer Nature, 2016-12)
    Background Data on the haematological outcomes of patients who continue clozapine treatment following neutropenia are very rare as even mild neutropenia results in mandatory discontinuation of clozapine in most countries. However, in Iceland where ...
  • Icon
    POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression 
    Gudmundsdottir, Bjorg; Gudmundsson, Kristbjorn Orri; Klarmann, Kimberly D.; Singh, Satyendra K.; Sun, Lei; Singh, Shweta; Du, Yang; Coppola, Vincenzo; Stockwin, Luke; Nguyen, Nhu; Tessarollo, Lino; Thorsteinsson, Leifur; Sigurjonsson, Olafur; Gudmundsson, Sveinn Vidar; Rafnar, Thorunn; Tisdale, John F.; Keller, Jonathan R. (Elsevier BV, 2018-06-12)
    Fetal globin genes are transcriptionally silenced during embryogenesis through hemoglobin switching. Strategies to derepress fetal globin expression in the adult could alleviate symptoms in sickle cell disease and β-thalassemia. We identified a zinc-finger ...