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Fletta eftir efnisorði "Autoantibodies"

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Cartilage destruction in early rheumatoid arthritis patients correlates with CD21-/low double-negative B cells

Þórarinsdóttir, Katrín; McGrath, Sarah; Forslind, Kristina; Agelii, Monica Leu; Ekwall, Anna-Karin Hultgård; Jacobsson, Lennart T H; Rudin, Anna; Mårtensson, Inga-Lill; Gjertsson, Inger (2024-01-15)

BACKGROUND: Involvement of B cells in the pathogenesis of rheumatoid arthritis (RA) is supported by the presence of disease-specific autoantibodies and the efficacy of treatment directed against B cells. B cells that express low levels of or lack the ...
Plasma interferon-alpha is associated with double-positivity for autoantibodies but is not a predictor of remission in early rheumatoid arthritis—a spin-off study of the NORD-STAR randomized clinical trial

Stockfelt, Marit; Lundell, Anna Carin; Hetland, Merete Lund; Østergaard, Mikkel; Uhlig, Till; Heiberg, Marte Schrumpf; Haavardsholm, Espen A.; Nurmohamed, Michael T.; Lampa, Jon; Nordström, Dan; Petersen, Kim Hørslev; Guðbjörnsson, Björn; Gröndal, Gerður; Aldridge, Jonathan; Andersson, Kerstin; Blennow, Kaj; Zetterberg, Henrik; van Vollenhoven, Ronald; Rudin, Anna (2021-07-13)

Background: The type I interferon (IFN) gene signature is present in a subgroup of patients with early rheumatoid arthritis (RA). Protein levels of IFNα have not been measured in RA and it is unknown whether they associate with clinical characteristics ...
Presence of autoantibodies in “seronegative” rheumatoid arthritis associates with classical risk factors and high disease activity

Reed, Evan; Hedström, Anna Karin; Hansson, Monika; Mathsson-Alm, Linda; Brynedal, Boel; Saevarsdottir, Saedis; Cornillet, Martin; Jakobsson, Per-Johan; Holmdahl, Rikard; Skriner, Karl; Serre, Guy; Alfredsson, Lars; Rönnelid, Johan; Lundberg, Karin (Springer Science and Business Media LLC, 2020-07-16)

Background: Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using anti-cyclic ...

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Fletta eftir efnisorði "Autoantibodies"

Fletta eftir efnisorði "Autoantibodies"

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