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Browsing by Subject "Aukaverkanir lyfja"

Browsing by Subject "Aukaverkanir lyfja"

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    Adverse drug reactions of antipsychotic drug treatment – how to balance evidence and values in relation to the use of clozapine in treatment-resistant schizophrenia 
    Ingimarsson, Oddur (University of Iceland, School of Health Sciences, Faculty of Medicine, 2018-04-10)
    Background: Schizophrenia is a chronic serious mental disorder with prevalence close to 0.7%. Early symptoms of schizophrenia generally appear in late adolescence or the early twenties. The prognosis is usually worse in cases of early onset. The ...
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    HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry 
    Konte, Bettina; Walters, James T.R.; Rujescu, Dan; Legge, Sophie E.; Pardiñas, Antonio F.; Cohen, Dan; Pirmohamed, Munir; Tiihonen, Jari; Hartmann, Annette M.; Bogers, Jan P.; van der Weide, Jan; van der Weide, Karen; Putkonen, Anu; Repo-Tiihonen, Eila; Hallikainen, Tero; Silva, Ed; Ingimarsson, Oddur; Sigurðsson, Engilbert; Kennedy, James L.; Sullivan, Patrick F.; Rietschel, Marcella; Breen, Gerome; Stefansson, Hreinn; Stefansson, Kari; Collier, David A.; O’Donovan, Michael C.; Giegling, Ina (2021-04-12)
    The atypical antipsychotic clozapine is the only effective medication for treatment-resistant schizophrenia. However, it can also induce serious adverse drug reactions, including agranulocytosis and neutropenia. The mechanism by which it does so is ...
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    Óráð og hiti – sjaldgæf en hættuleg orsök. : Sjúkratilfelli 
    Jóhannesson, Jón M.; Harðardóttir, Hrönn; Gudmundsson, Bjarni; Guðmundsson, Gunnar (2021-07-01)
    Sótthiti með óráði er algengt vandamál á bráðamóttökum og legudeildum sjúkrahúsa. Mismunagreiningar eru fjöldamargar og við uppvinnslu þessara sjúklinga er mikilvægt að hafa þær allar í huga. Sýkingar eru ofarlega á lista vegna bráð- og alvarleika en ...
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    Role of Corticosteroids in Drug-Induced Liver Injury. A Systematic Review 
    Björnsson, Einar Stefán; Vucic, Vesna; Stirnimann, Guido; Robles-Díaz, Mercedes (2022-02-10)
    Introduction: Apart from cessation of the implicated agent leading to drug-induced liver injury (DILI), there is no standard therapy for DILI. Corticosteroids have been used in DILI, although their efficacy is unclear. Published data showed either ...