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Browsing by Department "Cancer Center"

Browsing by Department "Cancer Center"

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  • Liyanarachchi, Sandya; Gudmundsson, Julius; Ferkingstad, Egil; He, Huiling; Jónasson, Jón Gunnlaugur; Tragante, Vinicius; Asselbergs, Folkert W.; Xu, Li; Kiemeney, Lambertus A.; Netea-Maier, Romana T.; Mayordomo, Jose I.; Plantinga, Theo S.; Hjartarson, Hannes; Hrafnkelsson, Jón; Sturgis, Erich M.; Brock, Pamela; Nabhan, Fadi; Thorleifsson, Gudmar; Ringel, Matthew D.; Stefansson, Kari; de la Chapelle, Albert (2020-03-17)
    Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk. Most of these SNPs are common variants with small to moderate effect sizes. Here we assessed ...
  • Jakubowska, A; Rozkrut, D; Antoniou, A; Hamann, U; Scott, R J; McGuffog, L; Healy, S; Sinilnikova, O M; Rennert, G; Lejbkowicz, F; Flugelman, A; Andrulis, I L; Glendon, G; Ozcelik, H; Thomassen, M; Paligo, M; Aretini, P; Kantala, J; Aroer, B; von Wachenfeldt, A; Liljegren, A; Loman, N; Herbst, K; Kristoffersson, U; Rosenquist, R; Karlsson, P; Stenmark-Askmalm, M; Melin, B; Nathanson, K L; Domchek, S M; Byrski, T; Huzarski, T; Gronwald, J; Menkiszak, J; Cybulski, C; Serrano, P; Osorio, A; Cajal, T R; Tsitlaidou, M; Benítez, J; Gilbert, M; Rookus, M; Aalfs, C M; Kluijt, I; Boessenkool-Pape, J L; Meijers-Heijboer, H E J; Oosterwijk, J C; van Asperen, C J; Blok, M J; Nelen, M R; van den Ouweland, A M W; Seynaeve, C; van der Luijt, R B; Devilee, P; Easton, D F; Peock, S; Frost, D; Platte, R; Ellis, S D; Fineberg, E; Evans, D G; Lalloo, F; Eeles, R; Jacobs, C; Adlard, J; Davidson, R; Eccles, D; Cole, T; Cook, J; Godwin, A; Bove, B; Stoppa-Lyonnet, D; Caux-Moncoutier, V; Belotti, M; Tirapo, C; Mazoyer, S; Barjhoux, L; Boutry-Kryza, N; Pujol, P; Coupier, I; Peyrat, J-P; Vennin, P; Muller, D; Fricker, J-P; Venat-Bouvet, L; Jóhannsson, Óskar Þór; Isaacs, C; Schmutzler, R; Wappenschmidt, B; Meindl, A; Arnold, N; Varon-Mateeva, R; Niederacher, D; Sutter, C; Deissler, H; Preisler-Adams, S; Simard, J; Soucy, P; Durocher, F; Chenevix-Trench, G; Beesley, J; Chen, X; Rebbeck, T; Couch, F; Wang, X; Lindor, N; Fredericksen, Z; Pankratz, V S; Peterlongo, P; Bonanni, B; Fortuzzi, S; Peissel, B; Szabo, C; Mai, P L; Loud, J T; Lubinski, J (2012-06-05)
    The variable penetrance of breast cancer in BRCA1/2 mutation carriers suggests that other genetic or environmental factors modify breast cancer risk. Two genes of special interest are prohibitin (PHB) and methylene-tetrahydrofolate reductase (MTHFR), ...
  • Sigurbergsdóttir, Aðalbjörg Ýr; Love, Thorvardur Jon; Kristinsson, Sigurður Yngvi (2022-04-28)
    Various epidemiological studies, including case reports and -series in addition to larger, population-based studies, have reported an increased prevalence of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma in individuals ...
  • Long, Þórir Einarsson; Indridason, Ólafur Skúli; Pálsson, Runólfur; Rögnvaldsson, Sæmundur; Löve, Þorvarður Jón; Thorsteinsdóttir, Sigrún; Sverrisdottir, Ingigerdur; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurðardóttir, Margrét; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Thordardottir, Asdis Rosa; Eyþórsson, Elías Sæbjörn; Jónsson, Ásbjörn; Gíslason, Gauti Kjartan; Ólafsson, Andri; Steingrímsdóttir, Hlíf; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2022-09-14)
    Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 ...
  • Shah, Urvi A.; Rögnvaldsson, Sæmundur; Derkach, Andriy; Björkholm, Magnus; Turesson, Ingemar; David, Yael; Hultcrantz, Malin; Tan, Carlyn; Hassoun, Hani; Korde, Neha; Lesokhin, Alexander; Mailankody, Sham; Kristinsson, Sigurður Yngvi; Ola Landgren, C. (2022-01-01)
  • The PRACTICAL consortium (2019-12-01)
    The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected in both the PDF and HTML versions ...
  • Thorsteinsdottir, Sigrun; Gislason, Gauti; Aspelund, Thor; Sverrisdottir, Ingigerdur; Landgren, Ola; Turesson, Ingemar; Björkholm, Magnus; Kristinsson, Sigurður Yngvi (2020-04-01)
    Multiple myeloma causes lytic bone lesions and fractures. The impact of fractures on multiple myeloma (MM) survival is unclear. The aim of this study was to evaluate the effect of fractures on survival in MM using data from MM patients diagnosed in ...
  • Liu, Xiaoyan; Swen, Jesse J.; Diekstra, Meta H.M.; Boven, Epie; Castellano, Daniel; Gelderblom, Hans; Mathijssen, Ron H.J.; Vermeulen, Sita H.; Oosterwijk, Egbert; Junker, Kerstin; Roessler, Max; Alexiusdottir, Kristin; Sverrisdóttir, Ásgerður; Radu, Marius T.; Ambert, Valentin; Eisen, Tim; Warren, Anne; Rodríguez-Antona, Cristina; García-Donas, Jesus; Böhringer, Stefan; Koudijs, Karel K.M.; Kiemeney, Lambertus A.L.M.; Rini, Brian I.; Guchelaar, Henk-Jan (2018-05-15)
    Purpose: The survival of patients with clear cell metastatic renal cell carcinoma (cc-mRCC) has improved substantially since the introduction of tyrosine kinase inhibitors (TKI). With the fact that TKIs interact with immune responses, we investigated ...
  • Wadsworth, Lauren P.; Wessman, Inga Dröfn; Björnsson, Andri Steinþór; Jónsdóttir, Guðbjörg; Kristinsson, Sigurður Yngvi (2022-09-23)
    Cancer screening is recommended for select cancers worldwide. Cancer screening has become increasingly effective and accessible and often increases overall survival. However, the mental health effects of cancer screening, such as its impact on depression, ...
  • Amirfallah, Arsalan; Knutsdottir, Hildur; Arason, Aðalgeir; Hilmarsdóttir, Bylgja; Jóhannsson, Óskar Þór; Agnarsson, Bjarni Agnar; Barkardottir, Rosa B.; Reynisdottir, Inga (2021-11-19)
    Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to be an oncomiR in most cancer types, including breast cancer. Most of the effects ...
  • Rögnvaldsson, Sæmundur; Love, Thorvardur Jon; Thorsteinsdottir, Sigrun; Reed, Elín Ruth; Óskarsson, Jón Þórir; Pétursdóttir, Íris; Sigurðardóttir, Guðrún Ásta; Viðarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni A.; Þorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Þórðardóttir, Ásdís Rósa; Eyþórsson, Elías; Jónsson, Ásbjörn; Björnsson, Andri S.; Gunnarsson, Gunnar Þór; Pálsson, Runólfur; Indriðason, Ólafur Skúli; Gíslason, Gauti Kjartan; Ólafsson, Andri; Hákonardóttir, Guðlaug Katrín; Brinkhuis, Manje; Halldórsdóttir, Sara Lovísa; Ásgeirsdóttir, Tinna Laufey; Steingrímsdóttir, Hlíf; Danielsen, Ragnar; Dröfn Wessman, Inga; Kampanis, Petros; Hulcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Kristinsson, Sigurður Yngvi (2021-05-17)
    Monoclonal gammopathy of undetermined significance (MGUS) precedes multiple myeloma (MM). Population-based screening for MGUS could identify candidates for early treatment in MM. Here we describe the Iceland Screens, Treats, or Prevents Multiple Myeloma ...
  • Saevarsdóttir, Karen Sól; Hilmarsdóttir, Hildur Ýr; Magnúsdóttir, Ingibjörg; Hauksdóttir, Arna; Thordardottir, Edda Bjork; Gudjónsdóttir, Ásdís Braga; Tomasson, Gunnar; Rúnarsdóttir, Harpa; Jónsdóttir, Harpa Lind; Gudmundsdóttir, Berglind; Pétursdóttir, Gudrún; Petersen, Pétur Henry; Kristinsson, Sigurdur Yngvi; Love, Thorvardur Jon; Hansdóttir, Sif; Hardardóttir, Hrönn; Gudmundsson, Gunnar; Eythorsson, Elias; Gudmundsdóttir, Dóra Gudrún; Sigbjörnsdóttir, Hildur; Haraldsdóttir, Sigrídur; Möller, Alma Dagbjört; Palsson, Runolfur; Jakobsdóttir, Jóhanna; Aspelund, Thor; Valdimarsdottir, Unnur (2021-07-23)
    Objective To test if patients recovering from COVID-19 are at increased risk of mental morbidities and to what extent such risk is exacerbated by illness severity. Design Population-based cross-sectional study. Setting Iceland. Participants A total of ...
  • Murray, David L.; Puig, Noemi; Kristinsson, Sigurður Yngvi; Usmani, Saad Z.; Dispenzieri, Angela; Bianchi, Giada; Kumar, Shaji; Chng, Wee Joo; Hajek, Roman; Paiva, Bruno; Waage, Anders; Rajkumar, S. Vincent; Durie, Brian (2021-02-01)
    Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect and isotype M-proteins. Increasing ...
  • Rögnvaldsson, Sæmundur; Eythorsson, Elias; Thorsteinsdottir, Sigrun; Vidarsson, Brynjar; Önundarson, Páll Torfi; Agnarsson, Bjarni Agnar; Sigurdardottir, Margret; Thorsteinsdóttir, Ingunn; Ólafsson, Ísleifur; Runólfsdóttir, Hrafnhildur L.; Helgason, Dadi; Emilsdóttir, Arna Rut; Ágústsson, Arnar Snær; Björnsson, Aron Hjalti; Kristjánsdóttir, Gudrún; Thordardottir, Asdis Rosa; Indridason, Olafur Skuli; Jónsson, Ásbjörn; Gislason, Gauti Kjartan; Olafsson, Andri; Steingrímsdóttir, Hlíf; Kampanis, Petros; Hultcrantz, Malin; Durie, Brian G.M.; Harding, Stephen; Landgren, Ola; Palsson, Runolfur; Love, Thorvarður Jon; Kristinsson, Sigurdur Yngvi (2021-12-01)
    Multiple myeloma (MM) patients have increased risk of severe coronavirus disease 2019 (COVID-19) when infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Monoclonal gammopathy of undetermined significance (MGUS), the precursor of ...
  • Rögnvaldsson, Sæmundur; Steingrímsson, Vilhjálmur; Turesson, Ingemar; Björkholm, Magnus; Landgren, Ola; Kristinsson, Sigurður Yngvi (2020-11)
  • Toksvang, Linea Natalie; Als-Nielsen, Bodil; Bacon, Christopher; Bertasiute, Ruta; Duarte, Ximo; Escherich, Gabriele; Helgadottir, Elín Anna; Johannsdottir, Inga Rinvoll; Jónsson, Ólafur G.; Kozlowski, Piotr; Langenskjöld, Cecilia; Lepik, Kristi; Niinimäki, Riitta; Overgaard, Ulrik Malthe; Punab, Mari; Räty, Riikka; Segers, Heidi; van der Sluis, Inge; Smith, Owen Patrick; Strullu, Marion; Vaitkevičienė, Goda; Wik, Hilde Skuterud; Heyman, Mats; Schmiegelow, Kjeld (2022-05-02)
    Background: A critical challenge in current acute lymphoblastic leukemia (ALL) therapy is treatment intensification in order to reduce the relapse rate in the subset of patients at the highest risk of relapse. The year-long maintenance phase is essential ...