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Fletta eftir höfundi "Halldórsson, Skarphéðinn"

Fletta eftir höfundi "Halldórsson, Skarphéðinn"

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    Cerebrospinal Fluid C18 Ceramide Associates with Markers of Alzheimer's Disease and Inflammation at the Pre- And Early Stages of Dementia 
    Teitsdóttir, Unnur Diljá; Halldórsson, Skarphéðinn; Rolfsson, Óttar; Lund, Sigrún H.; Jónsdóttir, María Kristín; Snædal, Jón G.; Petersen, Pétur Henry (2021-05-04)
    BACKGROUND: Understanding how dysregulation in lipid metabolism relates to the severity of Alzheimer's disease (AD) pathology might be critical in developing effective treatments. OBJECTIVE: To identify lipid species in cerebrospinal fluid (CSF) ...
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    Inhibition of PTP1B disrupts cell–cell adhesion and induces anoikis in breast epithelial cells 
    Hilmarsdóttir, Bylgja; Briem, Eiríkur; Halldórsson, Skarphéðinn; Kricker, Jennifer; Ingthorsson, Saevar; Gústafsdóttir, Sigrún; Mælandsmo, Gunhild M; Magnusson, Magnus Karl; Gudjonsson, Thorarinn (Springer Nature, 2017-05-11)
    Protein tyrosine phosphatase 1B (PTP1B) is a well-known inhibitor of insulin signaling pathways and inhibitors against PTP1B are being developed as promising drug candidates for treatment of obesity. PTP1B has also been linked to breast cancer both as ...
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    Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification 
    McGarrity, Sarah; Anuforo, Ósk; Halldórsson, Haraldur; Bergmann, Andreas; Halldórsson, Skarphéðinn; Palsson, Sirus; Henriksen, Hanne H.; Johansson, Pär Ingemar; Rolfsson, Óttar (Springer Nature, 2018-05-01)
    Endothelial dysfunction contributes to sepsis outcome. Metabolic phenotypes associated with endothelial dysfunction are not well characterised in part due to difficulties in assessing endothelial metabolism in situ. Here, we describe the construction ...