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Fletta eftir höfundi "Sigurdsson, Stefan"

Fletta eftir höfundi "Sigurdsson, Stefan"

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    Breast cancer survival in Nordic BRCA2 mutation carriers—unconventional association with oestrogen receptor status 
    Olafsdottir, Elinborg J.; Borg, Ake; Jensen, Maj Britt; Gerdes, Anne Marie; Johansson, Anna L.V.; Barkardottir, Rosa B.; Johannsson, Oskar T.; Ejlertsen, Bent; Sønderstrup, Ida Marie Heeholm; Hovig, Eivind; Lænkholm, Anne Vibeke; Hansen, Thomas van Overeem; Olafsdottir, Gudridur H.; Rossing, Maria; Jonasson, Jon G.; Sigurdsson, Stefan; Loman, Niklas; Nilsson, Martin P.; Narod, Steven A.; Tryggvadottir, Laufey (2020-11-24)
    Background: The natural history of breast cancer among BRCA2 carriers has not been clearly established. In a previous study from Iceland, positive ER status was a negative prognostic factor. We sought to identify factors that predicted survival after ...
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    CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer 
    Frick, Elisabet; Gudjonsson, Thorkell; Eyfjörð, Jórunn Erla; Jonasson, Jon; Tryggvadóttir, Laufey; Stefansson, Olafur; Sigurdsson, Stefan (Impact Journals, LLC, 2019-07-23)
    Estrogen receptor-positive breast cancer is subdivided into subtypes LuminalA and LuminalB, based on different expression patterns. MicroRNA-190b has been reported to be up-regulated in estrogen receptor-positive breast cancers. In this study we aimed ...
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    Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer 
    Piqué, Laia; Martinez de Paz, Alexia; Piñeyro, David; Martínez-Cardús, Anna; Castro de Moura, Manuel; Llinàs-Arias, Pere; Setien, Fernando; Gomez-Miragaya, Jorge; Gonzalez-Suarez, Eva; Sigurdsson, Stefan; Jónasson, Jón G.; Villanueva, Alberto; Vidal, August; Davalos, Veronica; Esteller, Manel (Springer Science and Business Media LLC, 2019-08-13)
    Human tumors show altered patterns of protein isoforms that can be related to the dysregulation of messenger RNA alternative splicing also observed in transformed cells. Although somatic mutations in core spliceosome components and their associated ...
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    Estrogen receptor-positive breast cancer and adverse outcome in BRCA2 mutation carriers and young non-carrier patients 
    Vidarsdottir, Linda; Olafsdottir, Elinborg J.; Barkardóttir, Rósa Björk; Bjarnadóttir, Ólöf Kristjana; Jónasson, Jón Gunnlaugur; Sigurdsson, Stefan; Tryggvadottir, Laufey (2023-11-30)
    Estrogen receptor-positive (ER+) breast cancer generally confers a more favorable prognosis than ER-negative cancer, however, a different picture is emerging for BRCA2 mutation carriers and young patients. We used nationwide data from population-based ...