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Browsing by Author "Saevarsdottir, Saedis"

Browsing by Author "Saevarsdottir, Saedis"

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  • Cagnotto, Giovanni; Willim, Minna; Nilsson, Jan Åke; Compagno, Michele; Jacobsson, Lennart T.H.; Saevarsdottir, Saedis; Turesson, Carl (2020-01-22)
    Background: There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. ...
  • Westerlind, Helga; Rönnelid, Johan; Hansson, Monika; Alfredsson, Lars; Mathsson‐Alm, Linda; Serre, Guy; Cornillet, Martin; Holmdahl, Rikard; Jakobsson, Per‐Johan; Skriner, Karl; Klareskog, Lars; Saevarsdottir, Saedis; Askling, Johan (Wiley, 2020-09-07)
    Objective: To investigate the relationship between anti–citrullinated protein antibodies (ACPAs), specific ACPA subspecificities, rheumatoid factor (RF) isotypes, and incident cardiovascular (CV) events in patients with rheumatoid arthritis (RA). ...
  • Waldenlind, Kristin; Delcoigne, Bénédicte; Saevarsdottir, Saedis; Askling, Johan (BMJ, 2020-07-15)
    Objective: To investigate if autoimmune thyroid disease (AITD) impacts rheumatoid arthritis (RA) disease activity or response to methotrexate. Methods A nationwide register-based cohort study of 9 004 patients with new-onset RA from the Swedish ...
  • Kharlamova, Nastya; Hermanrud, Christina; Dunn, Nicky; Ryner, Malin; Hambardzumyan, Karen; Vivar Pomiano, Nancy; Marits, Per; Gjertsson, Inger; Saevarsdottir, Saedis; Pullerits, Rille; Fogdell-Hahn, Anna (Frontiers Media SA, 2020-07-21)
    A subgroup of patients treated with infliximab lose response to the treatment and one reason for this is the development of anti-drug antibodies (ADA). If used optimally, measuring drug and ADA level could lead to a more personalized and efficient ...
  • Westerlind, Helga; Palmqvist, Ida; Saevarsdottir, Saedis; Alfredsson, Lars; Klareskog, Lars; Di Giuseppe, Daniela (2021-08-07)
    BACKGROUND: Tea is a popular beverage around the world and has properties that can affect the immune system. The association between tea consumption and the risk of rheumatoid arthritis (RA), a chronic autoimmune disease primarily affecting the joints, ...
  • Saevarsdottir, Saedis; Stefansdottir, Lilja; Sulem, Patrick; Thorleifsson, Gudmar; Ferkingstad, Egil; Rutsdottir, Gudrun; Glintborg, Bente; Westerlind, Helga; Grondal, Gerdur; Loft, Isabella C.; Sorensen, Signe Bek; Lie, Benedicte A.; Brink, Mikael; Arlestig, Lisbeth; Arnthorsson, Asgeir Orn; Baecklund, Eva; Banasik, Karina; Bank, Steffen; Bjorkman, Lena I.; Ellingsen, Torkell; Erikstrup, Christian; Frei, Oleksandr; Gjertsson, Inger; Gudbjartsson, Daniel F.; Gudjonsson, Sigurjon A.; Halldorsson, Gisli H.; Hendricks, Oliver; Hillert, Jan; Hogdall, Estrid; Jacobsen, Søren; Jensen, Dorte Vendelbo; Jonsson, Helgi; Kastbom, Alf; Kockum, Ingrid; Kristensen, Salome; Kristjansdottir, Helga; Larsen, Margit H.; Linauskas, Asta; Hauge, Ellen Margrethe; Loft, Anne G.; Ludviksson, Bjorn R.; Lund, Sigrun H.; Markússon, Þorsteinn; Masson, Gisli; Melsted, Pall; Moore, Kristjan H.S.; Munk, Heidi; Nielsen, Kaspar R.; Norddahl, Gudmundur L.; Oddsson, Asmundur; Olafsdottir, Thorunn A.; Olason, Pall I.; Olsson, Tomas; Ostrowski, Sisse Rye; Hørslev-Petersen, Kim; Rognvaldsson, Solvi; Sanner, Helga; Silberberg, Gilad N.; Stefansson, Hreinn; Sørensen, Erik; Sørensen, Inge J.; Turesson, Carl; Bergman, Thomas; Alfredsson, Lars; Kvien, Tore K.; Brunak, Søren; Steinsson, Kristján; Andersen, Vibeke; Andreassen, Ole A.; Rantapää-Dahlqvist, Solbritt; Hetland, Merete Lund; Klareskog, Lars; Askling, Johan; Padyukov, Leonid; Pedersen, Ole B.V.; Thorsteinsdottir, Unnur; Jonsdottir, Ingileif; Stefansson, Kari; Saevarsdottir, Saedis (2022-08-01)
    Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) and seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) and ∼1 million ...
  • Reed, Evan; Hedström, Anna Karin; Hansson, Monika; Mathsson-Alm, Linda; Brynedal, Boel; Saevarsdottir, Saedis; Cornillet, Martin; Jakobsson, Per-Johan; Holmdahl, Rikard; Skriner, Karl; Serre, Guy; Alfredsson, Lars; Rönnelid, Johan; Lundberg, Karin (Springer Science and Business Media LLC, 2020-07-16)
    Background: Rheumatoid arthritis (RA) is classified as seropositive or seronegative, depending on the presence/absence of rheumatoid factor (RF), primarily IgM RF, and/or anti-citrullinated protein antibodies (ACPA), commonly detected using anti-cyclic ...