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Fletta eftir höfundi "Aithal, Guruprasad P"

Fletta eftir höfundi "Aithal, Guruprasad P"

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    Drug-induced liver injury due to nitrofurantoin : Similar clinical features, but different HLA risk alleles in an independent cohort 
    Daly, Ann K.; Björnsson, Einar Stefán; Lucena, M. Isabel; Andrade, Raul J.; Aithal, Guruprasad P. (2023-05)
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    Genetic Risk Factors in Drug-Induced Liver Injury Due to Isoniazid-Containing Antituberculosis Drug Regimens 
    Nicoletti, Paola; Devarbhavi, Harshad; Goel, Ashish; Venkatesan, Radha; Eapen, Chundamannil E.; Grove, Jane I.; Zafer, Samreen; Björnsson, Einar Stefán; Lucena, M. Isabel; Andrade, Raul J.; Pirmohamed, Munir; Wadelius, Mia; Larrey, Dominique; Maitland-van der Zee, Anke Hilse; Ibanez, Luisa; Watkins, Paul B.; Daly, Ann K.; Aithal, Guruprasad P. (2021-04)
    Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, especially in isoniazid (INH)-containing regimens. To investigate genetic risk factors, we performed a genomewide association study (GWAS) involving anti-TB ...
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    A new framework for advancing in drug-induced liver injury research. The Prospective European DILI Registry 
    Björnsson, Einar Stefán; Stephens, Camilla; Atallah, Edmond; Robles-Diaz, Mercedes; Alvarez-Alvarez, Ismael; Gerbes, Alexander; Weber, Sabine; Stirnimann, Guido; Kullak-Ublick, Gerd; Cortez-Pinto, Helena; Grove, Jane I.; Lucena, M. Isabel; Andrade, Raul J.; Aithal, Guruprasad P. (2023-01-01)
    Background & Aims: No multi-national prospective study of drug-induced liver injury (DILI) has originated in Europe. The design of a prospective European DILI registry, clinical features and short-term outcomes of the cases and controls is reported. ...
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    Prevention and management of idiosyncratic drug-induced liver injury : Systematic review and meta-analysis of randomised clinical trials 
    Niu, Hao; Sanabria-Cabrera, Judith; Alvarez-Alvarez, Ismael; Robles-Diaz, Mercedes; Stankevičiūtė, Simona; Aithal, Guruprasad P.; Björnsson, Einar Stefán; Andrade, Raul J.; Lucena, M. Isabel (2021-02)
    Conducting randomised clinical trials (RCTs) in idiosyncratic drug-induced liver injury (DILI) is challenging. This systematic review aims to summarise the design and findings of RCTs in the prevention and management of idiosyncratic DILI. A systematic ...
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    A revised electronic version of RUCAM for the diagnosis of DILI 
    Hayashi, Paul H; Lucena, M Isabel; Fontana, Robert J; Björnsson, Einar Stefán; Aithal, Guruprasad P; Barnhart, Huiman; Gonzalez-Jimenez, Andres; Yang, Qinghong; Gu, Jiezhun; Andrade, Raul J; Hoofnagle, Jay H (2022-07)
    BACKGROUND AND AIMS: Roussel Uclaf Causality Assessment Method (RUCAM) for DILI has been hindered by subjectivity and poor reliability. We sought to improve the RUCAM using data from the Drug-Induced Liver Injury Network (DILIN) and the Spanish DILI ...
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    Tandem mass tag-based quantitative proteomic profiling identifies candidate serum biomarkers of drug-induced liver injury in humans 
    Ravindra, Kodihalli C; Vaidya, Vishal S; Wang, Zhenyu; Federspiel, Joel D; Virgen-Slane, Richard; Everley, Robert A; Grove, Jane I; Stephens, Camilla; Ocana, Mireia F; Robles-Díaz, Mercedes; Isabel Lucena, M; Andrade, Raul J; Atallah, Edmond; Gerbes, Alexander L; Weber, Sabine; Cortez-Pinto, Helena; Fowell, Andrew J; Hussaini, Hyder; Björnsson, Einar Stefán; Patel, Janisha; Stirnimann, Guido; Verma, Sumita; Elsharkawy, Ahmed M; Griffiths, William J H; Hyde, Craig; Dear, James W; Aithal, Guruprasad P; Ramaiah, Shashi K (2023-03-03)
    Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. Here, we identify, confirm, and replicate the biomarker performance characteristics of ...